Production method of hop preparation, hop preparation, anti-inflammatory agent, food product and beverage, and oral product
    3.
    发明申请
    Production method of hop preparation, hop preparation, anti-inflammatory agent, food product and beverage, and oral product 审中-公开
    啤酒花制备,啤酒花制备,消炎剂,食品和饮料以及口服产品的生产方法

    公开(公告)号:US20100179227A1

    公开(公告)日:2010-07-15

    申请号:US12310559

    申请日:2007-08-21

    IPC分类号: A61K31/05 A61P29/00 A61P1/02

    摘要: A method for producing a preparation that can be used in the prevention and treatment of inflammatory diseases, including periodontitis caused by P. gingivalis. Specifically, the invention provides a method for producing a hop preparation comprising the following steps (1) to (3): (1) adjusting the pH of a polyphenol-containing liquid prepared from hop bracts to 6 to 7 and passing the liquid through a gel-type synthetic resin to allow components including useful substances to be adsorbed onto the resin; (2) washing the resin obtained in the step (1) with a 30 to 60% aqueous ethanol solution to elute unwanted substances, leaving the useful substances adsorbed to the resin; and (3) washing the resin obtained in the step (2) with a 70% or higher aqueous ethanol solution or ethanol to elute the components including the useful substances and forming the preparation from the eluted fraction.

    摘要翻译: 一种可用于预防和治疗由牙龈卟啉菌引起的牙周炎的炎性疾病的制剂的制备方法。 具体地说,本发明提供一种制备包含以下步骤(1)至(3)的啤酒花制备方法:(1)将由跳虱制备的含多酚液体的pH调节至6至7,并使液体通过 凝胶型合成树脂,使包含有用物质的成分吸附在树脂上; (2)用30〜60%乙醇水溶液洗涤工序(1)得到的树脂,洗脱不需要的物质,留下有用物质吸附在树脂上; 和(3)用70%或更高的乙醇水溶液或乙醇洗涤步骤(2)中得到的树脂,以洗脱含有有用物质的组分并从洗脱级分形成制剂。