公开(公告)号：US20170266053A1

公开(公告)日：2017-09-21

申请号：US15075141

申请日：2016-03-19

Applicant: Maria Rodriguez

Inventor： Maria Rodriguez

IPC: A61F13/12 ,  A61F7/03 ,  A61F13/02 ,  A61F9/04 ,  A61F13/00

CPC classification number: A61F13/124 ,  A61F7/03 ,  A61F9/04 ,  A61F13/00063 ,  A61F2007/0004 ,  A61F2007/0226 ,  A61F2013/00217

Abstract: The disposable eye patch further comprises a rim ember circumferentially attached to the second layer, wherein the rim member comprises an adhesive for sticking the eye patch to cover the human eye. The adhesive is a safe for contact with the human skin and can be easily removed and discarded after a single use. The disposable eye patch further comprises an absorbent layer attached to the first layer facing the outer surface of the eye.

公开(公告)号：US20080260761A1

公开(公告)日：2008-10-23

申请号：US11576554

申请日：2005-10-04

Applicant: Steffan F. Vartanian ,  Maria Rodriguez

Inventor： Steffan F. Vartanian ,  Maria Rodriguez

IPC: C07K14/435 ,  C12N15/11 ,  C12N15/12 ,  C12Q1/68 ,  C12N15/85 ,  C12N5/06 ,  C12P21/02 ,  C07K16/30 ,  G01N33/574 ,  A61K39/00 ,  A61K31/7088 ,  A61K38/17 ,  C07K14/00

CPC classification number: C07K14/4748 ,  A61K38/00

Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic ovarian cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating ovarian cancer and non-cancerous disease states in ovarian, identifying ovarian tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered ovarian tissue for treatment and research.

Abstract translation: 本发明涉及存在于正常和肿瘤性卵巢细胞中的新鉴定的核酸分子和多肽，包括核酸和多肽的片段，变体和衍生物。 本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。 本发明还涉及含有本发明的核酸分子，多肽，抗体，激动剂和拮抗剂以及使用这些组合物的方法的组合物。 这些用途包括鉴定，诊断，监测，分期，成像和治疗卵巢癌和非癌性疾病状态，确定卵巢组织，监测和鉴定和/或设计本发明多肽的激动剂和拮抗剂。 用途还包括基因治疗，转基因动物和细胞的生产，以及用于治疗和研究的工程化卵巢组织的生产。

公开(公告)号：US20060078913A1

公开(公告)日：2006-04-13

申请号：US11183261

申请日：2005-07-15

Applicant: Roberto Macina ,  Leah Turner ,  Steffan Vartanian ,  Shu-Hui Liu ,  Maria Rodriguez ,  Huei-Mei Chen

Inventor： Roberto Macina ,  Leah Turner ,  Steffan Vartanian ,  Shu-Hui Liu ,  Maria Rodriguez ,  Huei-Mei Chen

IPC: C12Q1/68 ,  C07H21/04

CPC classification number: C07K14/4748 ,  G01N33/57484

Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast, intestine and colon, lung, ovarian or prostate cancer and non-cancerous disease states in breast, intestine and colon, lung, ovarian or prostate, identifying breast, intestine and colon, lung, ovarian or prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast, intestine and colon, lung, ovarian or prostate tissue for treatment and research.

Abstract translation: 本发明涉及存在于正常和肿瘤细胞中的新鉴定的核酸分子和多肽，包括核酸和多肽的片段，变体和衍生物。 本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。 本发明还涉及含有本发明的核酸分子，多肽，抗体，激动剂和拮抗剂以及使用这些组合物的方法的组合物。 这些用途包括在乳腺，肠和结肠，肺，卵巢或前列腺中识别，诊断，监测，分期，成像和治疗乳腺，肠和结肠，肺，卵巢或前列腺癌和非癌性疾病状态，鉴定乳腺，肠和 结肠，肺，卵巢或前列腺组织，监测和鉴定和/或设计本发明多肽的激动剂和拮抗剂。 用途还包括基因治疗，转基因动物和细胞的产生以及工程乳房，肠和结肠，肺，卵巢或前列腺组织的生产用于治疗和研究。

公开(公告)号：US20220062589A1

公开(公告)日：2022-03-03

申请号：US17009058

申请日：2020-09-01

Applicant: Maria Rodriguez ,  Deborah Robinson

Inventor： Maria Rodriguez ,  Deborah Robinson

IPC: A61M25/02 ,  A61M1/28

Abstract: A catheter stabilizing device for stabilizing a Continuous Ambulatory Peritoneal Dialysis (CAPD) catheter includes a pad having an adhesive engaged to a first face thereof. The adhesive is used to engage the pad to abdominal skin of a user so that the pad is engaged to an abdomen of the user. A connector is engaged to a second face of the pad and can selectively connect to a tube of a catheter. The connector stabilizes the catheter in a selected position.

公开(公告)号：US20050272067A1

公开(公告)日：2005-12-08

申请号：US11077386

申请日：2005-03-10

Applicant: Roberto Macina ,  Leah Turner ,  Huei-Mei Chen ,  Maria Rodriguez ,  Shu-Hui Liu

Inventor： Roberto Macina ,  Leah Turner ,  Huei-Mei Chen ,  Maria Rodriguez ,  Shu-Hui Liu

IPC: C07H21/04 ,  C07K14/47 ,  C07K14/82 ,  C12N15/09 ,  C12Q1/68

CPC classification number: C07K14/4748

Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast, intestine and colon, lung, ovarian or prostate cancer and non-cancerous disease states in breast, intestine and colon, lung, ovarian or prostate, identifying breast, intestine and colon, lung, ovarian or prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast, intestine and colon, lung, ovarian or prostate tissue for treatment and research.

Abstract translation: 本发明涉及存在于正常和肿瘤细胞中的新鉴定的核酸分子和多肽，包括核酸和多肽的片段，变体和衍生物。 本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。 本发明还涉及含有本发明的核酸分子，多肽，抗体，激动剂和拮抗剂以及使用这些组合物的方法的组合物。 这些用途包括在乳腺，肠和结肠，肺，卵巢或前列腺中识别，诊断，监测，分期，成像和治疗乳腺，肠和结肠，肺，卵巢或前列腺癌和非癌性疾病状态，鉴定乳腺，肠和 结肠，肺，卵巢或前列腺组织，监测和鉴定和/或设计本发明多肽的激动剂和拮抗剂。 用途还包括基因治疗，转基因动物和细胞的产生以及工程乳房，肠和结肠，肺，卵巢或前列腺组织的生产用于治疗和研究。