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公开(公告)号：US06576007B2
公开(公告)日：2003-06-10
申请号：US09819539
申请日：2001-03-27
申请人： Mark Dehdashtian , Geoffrey H. White , Weiyun Yu
发明人： Mark Dehdashtian , Geoffrey H. White , Weiyun Yu
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/89 , A61F2/95 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2002/826 , A61F2220/0033 , A61F2250/0048 , A61F2250/0098
摘要： Methods and apparatus for placing a bifurcated aortic graft, with extensions, into a body lumen. An aortic graft is provided with a unique combination of self-expanding a balloon expandable wires. The aortic graft is bifurcated and includes ipsilateral and contralateral legs. Two extension grafts are provided for frictional engagement with the legs of the aortic graft. For placement of the bifurcated aortic graft with extensions, an introducer assembly including a dilator and a sheath assembly provides access for the introduction of a main catheter and a directional catheter. The main catheter is provided for deployment of the bifurcated aortic graft within the lumen of a vessel. A balloon is provided on the main catheter for expanding the balloon-expandable wires of the aortic graft. The directional catheter, which includes a deflecting spring portion, permits placement of a guidewire through the ipsilateral leg and into the contralateral leg of the aortic graft. In turn, a second introducer sheath and a second catheter assembly are provided contralaterally for introduction of a graft extension. Upon balloon-expansion, the graft extension is frictionally engaged with the contralateral leg of the aortic graft. A third catheter assembly including a second extension graft is provided for introduction of the extension graft and balloon-expansion thereof for frictional engagement with the ipsilateral leg of the graft.
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公开(公告)号：US5968068A
公开(公告)日：1999-10-19
申请号：US713070
申请日：1996-09-12
CPC分类号： A61F2/958 , A61M2039/062 , A61M2039/0633 , A61M2039/0646 , A61M2039/0653 , A61M2039/0686 , A61M39/06
摘要： A system for delivering and implanting a radially expandable endoluminal prosthesis within a body lumen (e.g., blood vessel). The system comprises a) an introducer/dilator assembly, and b) a delivery catheter/loader assembly. The introducer/dilator assembly comprises an elongate tubular introducer sheath which may be provided with a valving assembly mounted on the proximal end thereof. Such valving assembly may incorporate i) a hemostatic valve, ii) a first sealing valve and iii) a second sealing valve, positioned in series, to prevent leakage of body fluid out of the proximal end of the introducer and to permit two or more elongate members (e.g., catheters, guidewires) having differing outer diameters to be inserted through the introducer without leakage of body fluid therefrom. A dilator, which has regionalized differences in stiffness, is initially deployable within the lumen of the introducer to facilitate advancement of the introducer to its desired location within the body. Thereafter, the dilator may be removed from the introducer sheath and the delivery catheter/loader assembly may be attached to the introducer, such that the delivery catheter having the prosthesis mounted thereon may advanced through the introducer, to a desired location within the body. Thereafter, the radial expandable endoluminal prosthesis mounted on the delivery catheter is deployed and implanted by an expansion device (e.g., balloon) formed on the delivery catheter. The delivery catheter may incorporate one or more outflow apertures at specific location(s) to facilitate injection of radiographic contrast medium in a manner which will check for leakage around the endoluminal prosthesis, after the endoluminal prosthesis has been radially expanded and implanted.
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公开(公告)号：US06451053B1
公开(公告)日：2002-09-17
申请号：US09819534
申请日：2001-03-27
申请人： Mark Dehdashtian , Geoffrey H. White , Weiyun Yu
发明人： Mark Dehdashtian , Geoffrey H. White , Weiyun Yu
IPC分类号： A61F200
CPC分类号： A61F2/07 , A61F2/89 , A61F2/95 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2002/826 , A61F2220/0033 , A61F2250/0048 , A61F2250/0098
摘要： Methods and apparatus for placing a bifurcated aortic graft, with extensions, into a body lumen. An aortic graft is provided with a unique combination of self-expanding a balloon expandable wires. The aortic graft is bifurcated and includes ipsilateral and contralateral legs. Two extension grafts are provided for frictional engagement with the legs of the aortic graft. For placement of the bifurcated aortic graft with extensions, an introducer assembly including a dilator and a sheath assembly provides access for the introduction of a main catheter and a directional catheter. The main catheter is provided for deployment of the bifurcated aortic graft within the lumen of a vessel. A balloon is provided on the main catheter for expanding the balloon-expandable wires of the aortic graft. The directional catheter, which includes a deflecting spring portion, permits placement of a guidewire through the ipsilateral leg and into the contralateral leg of the aortic graft. In turn, a second introducer sheath and a second catheter assembly are provided contralaterally for introduction of a graft extension. Upon balloon-expansion, the graft extension is frictionally engaged with the contralateral leg of the aortic graft. A third catheter assembly including a second extension graft is provided for introduction of the extension graft and balloon-expansion thereof for frictional engagement with the ipsilateral leg of the graft.
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公开(公告)号：US06379372B1
公开(公告)日：2002-04-30
申请号：US09694736
申请日：2000-10-23
IPC分类号： A61M2900
CPC分类号： A61F2/958 , A61M39/06 , A61M2039/062 , A61M2039/0633 , A61M2039/0646 , A61M2039/0653 , A61M2039/0686
摘要： A system for delivering and implanting a radially expandable endoluminal prosthesis within a body lumen (e.g., blood vessel). The system comprises a) an introducer/dilator assembly, and b) a delivery catheter/loader assembly. The introducer/dilator assembly comprises an elongate tubular introducer sheath which may be provided with a valving assembly mounted on the proximal end thereof. Such valving assembly may incorporate i) a hemostatic valve, ii) a first sealing valve and iii) a second sealing valve, positioned in series, to prevent leakage of body fluid out of the proximal end of the introducer and to permit two or more elongate members (e.g., catheters, guidewires) having differing outer diameters to be inserted through the introducer without leakage of body fluid therefrom. A dilator, which has regionalized differences in stiffness, is initially deployable within the lumen of the introducer to facilitate advancement of the introducer to its desired location within the body. Thereafter, the dilator may be removed from the introducer sheath and the delivery catheter/loader assembly may be attached to the introducer, such that the delivery catheter having the prosthesis mounted thereon may advanced through the introducer, to a desired location within the body. Thereafter, the radial expandable endoluminal prosthesis mounted on the delivery catheter is deployed and implanted by an expansion device (e.g., balloon) formed on the delivery catheter. The delivery catheter may incorporate one or more outflow apertures at specific location(s) to facilitate injection of radiographic contrast medium in a manner which will check for leakage around the endoluminal prosthesis, after the endoluminal prosthesis has been radially expanded and implanted.
摘要翻译： 用于在体腔（例如，血管）内输送和植入径向可膨胀的腔内假体的系统。 该系统包括a）导引器/扩张器组件，以及b）输送导管/装载器组件。 导引器/扩张器组件包括细长的管状导引器护套，其可以设置有安装在其近端上的阀组件。 这种阀门组件可以包括i）止血阀，ii）第一密封阀和iii）串联定位的第二密封阀，以防止体液从引导器的近端泄漏出来并且允许两个或更多细长 具有不同外径的构件（例如，导管，导丝）插入穿过导引器而不会从其体内流体泄漏。 具有区域性的刚度差异的扩张器最初可部署在导引器的内腔内，以便于将导引器推进到其体内所需的位置。 此后，扩张器可以从引导器护套中移除，并且输送导管/装载器组件可以附接到导引器，使得具有安装在其上的假体的输送导管可以通过导引器前进到身体内的期望位置。 此后，安装在输送导管上的径向可膨胀的腔内假体通过形成在输送导管上的膨胀装置（例如气囊）展开和植入。 递送导管可以在特定位置包括一个或多个流出孔，以便于在腔内假体已被径向扩张和植入之后以一种将检查腔内假体周围的渗漏的方式注射射线照相造影剂。
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5.发明授权Methods and apparatus for intraluminal placement of a bifurcated intraluminal graft 有权腔内放置分叉腔内移植物的方法和装置公开(公告)号：US06375675B2
公开(公告)日：2002-04-23
申请号：US09819454
申请日：2001-03-27
申请人： Mark Dehdashtian , Geoffrey H. White , Weiyun Yu
发明人： Mark Dehdashtian , Geoffrey H. White , Weiyun Yu
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/89 , A61F2/95 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2002/826 , A61F2220/0033 , A61F2250/0048 , A61F2250/0098
摘要： Methods and apparatus for placing a bifurcated aortic graft, with extensions, into a body lumen. An aortic graft is provided with a unique combination of self-expanding a balloon expandable wires. The aortic graft is bifurcated and includes ipsilateral and contralateral legs. Two extension grafts are provided for frictional engagement with the legs of the aortic graft. For placement of the bifurcated aortic graft with extensions, an introducer assembly including a dilator and a sheath assembly provides access for the introduction of a main catheter and a directional catheter. The main catheter is provided for deployment of the bifurcated aortic graft within the lumen of a vessel. A balloon is provided on the main catheter for expanding the balloon-expandable wires of the aortic graft. The directional catheter, which includes a deflecting spring portion, permits placement of a guidewire through the ipsilateral leg and into the contralateral leg of the aortic graft. In turn, a second introducer sheath and a second catheter assembly are provided contralaterally for introduction of a graft extension. Upon balloon-expansion, the graft extension is frictionally engaged with the contralateral leg of the aortic graft. A third catheter assembly including a second extension graft is provided for introduction of the extension graft and balloon-expansion thereof for frictional engagement with the ipsilateral leg of the graft.
摘要翻译： 将具有延伸部的分叉主动脉移植物放置在体腔中的方法和装置。 主动脉移植物具有自扩张气囊可扩展电线的独特组合。 主动脉移植物分叉，包括同侧和对侧腿。 提供两个延伸移植物用于与主动脉移植物的腿摩擦接合。 为了安置具有延伸部的分叉主动脉移植物，包括扩张器和护套组件的导引器组件提供用于引入主导管和定向导管的通路。 提供主导管用于将分叉的主动脉移植物部署在血管的内腔内。 在主导管上设置有用于扩张主动脉移植物的球囊可扩张线的球囊。 包括偏转弹簧部分的定向导管允许将导丝穿过同侧腿并进入主动脉移植物的对侧腿部。 反过来，第二引导器护套和第二导管组件相对地设置以引入移植物延伸部。 气囊膨胀时，移植物延伸部与主动脉移植物的对侧腿摩擦接合。 提供包括第二延伸移植物的第三导管组件，用于引入延伸移植物和气囊扩张，以与移植物的同侧腿摩擦接合。
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公开(公告)号：US06368345B1
公开(公告)日：2002-04-09
申请号：US09204699
申请日：1998-12-03
申请人： Mark Dehdashtian , Geoffrey H. White , Weiyun Yu
发明人： Mark Dehdashtian , Geoffrey H. White , Weiyun Yu
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/89 , A61F2/95 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2002/826 , A61F2220/0033 , A61F2250/0048 , A61F2250/0098
摘要： Methods and apparatus for placing a bifurcated aortic graft, with extensions, into a body lumen. An aortic graft is provided with a unique combination of self-expanding a balloon expandable wires. The aortic graft is bifurcated and includes ipsilateral and contralateral legs. Two extension grafts are provided for frictional engagement with the legs of the aortic graft. For placement of the bifurcated aortic graft with extensions, an introducer assembly including a dilator and a sheath assembly provides access for the introduction of a main catheter and a directional catheter. The main catheter is provided for deployment of the bifurcated aortic graft within the lumen of a vessel. A balloon is provided on the main catheter for expanding the balloon-expandable wires of the aortic graft. The directional catheter, which includes a deflecting spring portion, permits placement of a guidewire through the ipsilateral leg and into the contralateral leg of the aortic graft. In turn, a second introducer sheath and a second catheter assembly are provided contralaterally for introduction of a graft extension. Upon balloon-expansion, the graft extension is frictionally engaged with the contralateral leg of the aortic graft. A third catheter assembly including a second extension graft is provided for introduction of the extension graft and balloon-expansion thereof for frictional engagement with the ipsilateral leg of the graft.
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公开(公告)号：US06231563B1
公开(公告)日：2001-05-15
申请号：US09117092
申请日：1999-04-14
申请人： Geoffrey H. White , Weiyun Yu , Mark Dehdashtian
发明人： Geoffrey H. White , Weiyun Yu , Mark Dehdashtian
IPC分类号： A61M2500
CPC分类号： A61M25/01 , A61M25/09 , A61M2025/0034 , A61M2025/0037 , A61M2025/018
摘要： An intraluminal catheter for directing a guidewire and/or catheter in a desired direction within a bodily vessel or cavity. The intraluminal catheter has a first elongate tubular member and a support means which can comprise a second elongate tubular member that can pass over a main support guidewire. The catheter acts as a platform as the guidewire is passed through the first elongate tubular member and is deflected transversely outwardly by an angled surface through an aperture. A second intraluminal catheter has a first elongate tubular member and a support means comprising a second elongate tubular member. The first elongate tubular member has a main portion and an end portion, with the end portion being deflectable relative to the locus of the main portion so as to direct the guidewire passing through the end portion in a desired direction in the bodily vessel.
摘要翻译： 一种用于将导丝和/或导管沿着所需方向引导到体内血管或空腔内的管腔内导管。 管腔内导管具有第一细长管状构件和支撑装置，该支撑装置可包括可穿过主支撑导丝的第二细长管状构件。 当导丝穿过第一细长管状构件时，导管用作平台，并且通过孔径横向向外偏转成角度的表面。 第二腔内导管具有第一细长管状构件和包括第二细长管状构件的支撑装置。 第一细长管状构件具有主体部分和端部部分，其端部相对于主要部分的轨迹是可偏转的，以便引导导线沿着所需方向在身体容器中穿过端部。
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公开(公告)号：US6143014A
公开(公告)日：2000-11-07
申请号：US364430
申请日：1999-07-30
CPC分类号： A61F2/958 , A61M2039/062 , A61M2039/0633 , A61M2039/0646 , A61M2039/0653 , A61M2039/0686 , A61M39/06
摘要： A system for delivering and implanting a radially expandable endoluminal prosthesis within a body lumen (e.g., blood vessel). The system comprises a) an introducer/dilator assembly, and b) a delivery catheter/loader assembly. The introducer/dilator assembly comprises an elongate tubular introducer sheath which may be provided with a valving assembly mounted on the proximal end thereof. Such valving assembly may incorporate i) a hemostatic valve, ii) a first sealing valve and iii) a second sealing valve, positioned in series, to prevent leakage of body fluid out of the proximal end of the introducer and to permit two or more elongate members (e.g., catheters, guidewires) having differing outer diameters to be inserted through the introducer without leakage of body fluid therefrom. A dilator, which has regionalized differences in stiffness, is initially deployable within the lumen of the introducer to facilitate advancement of the introducer to its desired location within the body. Thereafter, the dilator may be removed from the introducer sheath and the delivery catheter/loader assembly may be attached to the introducer, such that the delivery catheter having the prosthesis mounted thereon may advanced through the introducer, to a desired location within the body. Thereafter, the radial expandable endoluminal prosthesis mounted on the delivery catheter is deployed and implanted by an expansion device (e.g., balloon) formed on the delivery catheter. The delivery catheter may incorporate one or more outflow apertures at specific location(s) to facilitate injection of radiographic contrast medium in a manner which will check for leakage around the endoluminal prosthesis, after the endoluminal prosthesis has been radially expanded and implanted.
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公开(公告)号：US6110191A
公开(公告)日：2000-08-29
申请号：US203998
申请日：1998-12-01
CPC分类号： A61F2/958 , A61M2039/062 , A61M2039/0633 , A61M2039/0646 , A61M2039/0653 , A61M2039/0686 , A61M39/06
摘要： A system for delivering and implanting a radially expandable endoluminal prosthesis within a body lumen (e.g., blood vessel). The system comprises a) an introducer/dilator assembly, and b) a delivery catheter/loader assembly. The introducer/dilator assembly comprises an elongate tubular introducer sheath which may be provided with a valving assembly mounted on the proximal end thereof. Such valving assembly may incorporate i) a hemostatic valve, ii) a first sealing valve and iii) a second sealing valve, positioned in series, to prevent leakage of body fluid out of the proximal end of the introducer and to permit two or more elongate members (e.g., catheters, guidewires) having differing outer diameters to be inserted through the introducer without leakage of body fluid therefrom. A dilator, which has regionalized differences in stiffness, is initially deployable within the lumen of the introducer to facilitate advancement of the introducer to its desired location within the body. Thereafter, the dilator may be removed from the introducer sheath and the delivery catheter/loader assembly may be attached to the introducer, such that the delivery catheter having the prosthesis mounted thereon may advanced through the introducer, to a desired location within the body. Thereafter, the radial expandable endoluminal prosthesis mounted on the delivery catheter is deployed and implanted by an expansion device (e.g., balloon) formed on the delivery catheter. The delivery catheter may incorporate one or more outflow apertures at specific location(s) to facilitate injection of radiographic contrast medium in a manner which will check for leakage around the endoluminal prosthesis, after the endoluminal prosthesis has been radially expanded and implanted.
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公开(公告)号：US06685736B1
公开(公告)日：2004-02-03
申请号：US09478413
申请日：2000-01-06
申请人： Geoffrey H. White , Weiyun Yu
发明人： Geoffrey H. White , Weiyun Yu
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/86 , A61F2/89 , A61F2/958 , A61F2002/075
摘要： An intraluminal graft includes a tubular graft body extending along a cylindrical axis, a plurality of wires spaced apart from each other and arranged to circumferentially reinforce said tubular graft body along a substantial portion of its length, and a body surface including an inner surface region and an outer surface region. The body surface defines a plurality of apertures extending from an exterior space, and a first portion of a first wire is in the interior space while a second portion of the first wire is in the exterior space.
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