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    Apparatus for discrimination of stable and unstable ventricular tachycardia and for treatment thereof
    1.
    发明授权
    Apparatus for discrimination of stable and unstable ventricular tachycardia and for treatment thereof 失效
    用于辨别稳定和不稳定的静脉卡车的装置及其处理方法

    公开(公告)号：US5176137A

    公开(公告)日：1993-01-05

    申请号：US663985

    申请日：1991-03-01

    申请人： Mark K. Erickson ,  Tom D. Bennett

    发明人： Mark K. Erickson ,  Tom D. Bennett

    IPC分类号： A61N1/362 ,  A61N1/365 ,  A61N1/39

    CPC分类号： A61N1/3962 ,  A61N1/3622 ,  A61N1/36557

    摘要： A method and apparatus for discriminating between stable and unstable ventricular tachycardias based on a measurement of oxygen saturation. Reference values for average oxygen saturation level and of the pulsatile characteristic of the oxygen saturation level are taken while a patient is in a resting condition. Measurements of oxygen saturation are also taken in response to the detection of a high heart rate, and are compared to the reference measurements to discriminate between stable and unstable ventricular tachyarrhythmias. An unstable tachyarrhythmia is diagnosed if a tachycardia is diagnosed and the current oxygen saturation level is similar to the reference average oxygen saturation level or if the oxygen saturation as presently measured displays a decreased pulsatile characteristic as compared to the reference measurements. The discriminator is intended for use in conjunction with or as part of an automated cardioverter of the type capable of delivering differing therapies for termination of stable and unstable ventricular tachyarrhythmias, such as antitachycardia pacing, cardioversion and defibrillation.

    摘要翻译： 一种基于氧饱和度测量来区分稳定性和不稳定性室性心动过速的方法和装置。 当患者处于静止状态时，采用平均氧饱和度水平和氧饱和度的脉动特性的参考值。 响应于高心率的检测也测量氧饱和度，并且与参考测量值进行比较以区分稳定和不稳定的室性快速性心律失常。 如果诊断出心动过速并且目前的氧饱和度水平与参考平均氧饱和度水平相似，或如果目前测量的氧饱和度与参考测量值相比显示出降低的脉动特性，则诊断出不稳定的快速性心律失常。 鉴别器旨在与能够递送用于终止稳定和不稳定的室性快速性心律失常的类型的自动心律转复器的一部分一起使用，例如抗心动过速起搏，复律和除颤。

    TECHNIQUES FOR MODIFYING BREATHING RATE USING CARDIAC PACING
    2.
    发明申请
    TECHNIQUES FOR MODIFYING BREATHING RATE USING CARDIAC PACING 有权
    用CARDIAC PACING修改呼吸速率的技术

    公开(公告)号：US20120290032A1

    公开(公告)日：2012-11-15

    申请号：US13103839

    申请日：2011-05-09

    申请人： Yong Kyun Cho ,  Mark K. Erickson ,  Tommy D. Bennett

    发明人： Yong Kyun Cho ,  Mark K. Erickson ,  Tommy D. Bennett

    IPC分类号： A61N1/365

    CPC分类号： A61N1/056 ,  A61N1/3611 ,  A61N1/36114

    摘要： A method includes controlling a cardiac pacing rate of an implantable medical device (IMD) to control a heart rate of a patient and determining that the patient is in a resting state. The method further includes modifying the pacing rate of the IMD for N cardiac cycles in response to determining that the patient is in the resting state. N is an integer greater than 1. Modifying the pacing rate includes incrementally increasing the pacing rate for a first portion of the N cardiac cycles, and incrementally decreasing the pacing rate for a second portion of the N cardiac cycles.

    摘要翻译： 一种方法包括控制可植入医疗装置（IMD）的心脏起搏速率以控制患者的心率并确定患者处于静止状态。 所述方法还包括响应于确定患者处于静止状态而修改IM心脏起搏速率的N个心动周期。 N是大于1的整数。修改起搏速率包括逐渐增加N个心动周期的第一部分的起搏速率，并逐渐降低N个心动周期的第二部分的起搏速率。

    Method and apparatus for detecting respiratory disturbances
    5.
    发明授权
    Method and apparatus for detecting respiratory disturbances 有权
    用于检测呼吸障碍的方法和装置

    公开(公告)号：US07524292B2

    公开(公告)日：2009-04-28

    申请号：US11565092

    申请日：2006-11-30

    申请人： Yong K. Cho ,  Steven L. Ning ,  Luc R. Mongeon ,  Scott W. Davie ,  Todd J. Sheldon ,  Mark K. Erickson ,  H. Toby Markowitz

    发明人： Yong K. Cho ,  Steven L. Ning ,  Luc R. Mongeon ,  Scott W. Davie ,  Todd J. Sheldon ,  Mark K. Erickson ,  H. Toby Markowitz

    IPC分类号： A61B5/08 ,  A61B5/02 ,  A61B5/00 ,  A61B5/103 ,  A61B5/05

    CPC分类号： A61B5/0809 ,  A61B5/0205 ,  A61B5/0215 ,  A61B5/0402 ,  A61B5/1459 ,  A61B5/4818 ,  G06F19/00

    摘要： A system and method for monitoring respiration including sensing a signal that varies with respiration, deriving a respiration parameter, applying criteria for detecting a respiration disturbance and determining one or more respiratory disturbance metrics. The system preferably includes an implantable sensor with an associated implantable medical device such that chronic respiration monitoring is possible. The implantable medical device may execute methods for detecting and measuring respiratory disturbances or may store data to be transferred to an external device for detecting and measuring respiratory disturbances. Respiratory disturbance detection may trigger a responsive action such as physiological data storage, a change in therapy delivery, or a clinician warning. Assessment of cardiac function may be made based on metrics of respiratory disturbances or a measure of circulatory delay time following detection of a respiratory disturbance.

    摘要翻译： 一种用于监测呼吸的系统和方法，包括感测随呼吸变化的信号，导出呼吸参数，应用用于检测呼吸障碍的标准和确定一个或多个呼吸障碍度量。 该系统优选地包括具有相关联的可植入医疗装置的可植入传感器，使得可以进行慢性呼吸监测。 可植入医疗装置可以执行用于检测和测量呼吸障碍的方法，或者可以将要传送到外部设备的数据存储以检测和测量呼吸障碍。 呼吸道干扰检测可能会触发响应动作，如生理数据存储，治疗传递的变化或临床医生的警告。 心脏功能的评估可以基于呼吸紊乱的度量或检测到呼吸障碍之后的循环延迟时间的量度进行。

    Methods and apparatus for detection and treatment of syncope
    6.
    发明授权
    Methods and apparatus for detection and treatment of syncope 有权
    用于晕厥检测和治疗的方法和装置

    公开(公告)号：US06895275B2

    公开(公告)日：2005-05-17

    申请号：US10053762

    申请日：2002-01-22

    申请人： Harold Toby Markowitz ,  Mark K. Erickson ,  Alan V. Sahakian ,  Andreas Schuler

    发明人： Harold Toby Markowitz ,  Mark K. Erickson ,  Alan V. Sahakian ,  Andreas Schuler

    IPC分类号： A61B5/05 ,  A61B5/0402 ,  A61N1/365 ,  A61N1/362

    CPC分类号： A61N1/36521

    摘要： The present invention relates to methods and apparatus for detection and treatment of syncope in an implantable medical device, and particularly to detection of syncope as a function of a predetermined increase in one or more respiration parameter and drop in heart rate and optionally delivering a pacing therapy in response thereto. The onset of a syncopal episode is declared when the patient's respiration rate and/or tidal volume and/or minute ventilation increases by a predetermined increment or threshold and a heart rate drops below a threshold heart rate drop. The threshold heart rate drop is preferably established as a function of the change in the respiration parameter.

    摘要翻译： 本发明涉及用于在可植入医疗装置中检测和治疗晕厥的方法和装置，特别涉及作为一个或多个呼吸参数的预定增加和心率下降以及可选地递送起搏疗法的功能的晕厥检测 作为响应。 当患者的呼吸速率和/或潮气量和/或分钟通气增加预定的增量或阈值并且心率下降到阈值心率下降以下时，宣布间歇发作的发作。 阈值心率下降优选地建立为呼吸参数变化的函数。

    Techniques for modifying breathing rate using cardiac pacing
    7.
    发明授权
    Techniques for modifying breathing rate using cardiac pacing 有权
    使用心脏起搏改善呼吸频率的技术

    公开(公告)号：US08483833B2

    公开(公告)日：2013-07-09

    申请号：US13103861

    申请日：2011-05-09

    申请人： Yong Kyun Cho ,  Mark K. Erickson ,  Tommy D. Bennett

    发明人： Yong Kyun Cho ,  Mark K. Erickson ,  Tommy D. Bennett

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36114 ,  A61N1/056 ,  A61N1/3611

    摘要： A method includes controlling a cardiac pacing rate of an implantable medical device to control a heart rate of a patient and detecting inhalation and exhalation of the patient. The method further includes determining that the patient is in a resting state, and, in response to determining that the patient is in the resting state, incrementally increasing the pacing rate while exhalation of the patient is detected and incrementally decreasing the pacing rate while inhalation of the patient is detected.

    摘要翻译： 一种方法包括控制可植入医疗装置的心脏起搏速率以控制患者的心率并检测患者的吸入和呼气。 该方法还包括确定患者处于静止状态，并且响应于确定患者处于静止状态，逐渐增加起搏速率，同时检测到患者的呼气，并逐渐降低起搏速率，同时吸入 检测到患者。

    Techniques for modifying breathing rate using cardiac pacing
    8.
    发明授权
    Techniques for modifying breathing rate using cardiac pacing 有权
    使用心脏起搏改善呼吸频率的技术

    公开(公告)号：US08467870B2

    公开(公告)日：2013-06-18

    申请号：US13103839

    申请日：2011-05-09

    申请人： Yong Kyun Cho ,  Mark K. Erickson ,  Tommy D. Bennett

    发明人： Yong Kyun Cho ,  Mark K. Erickson ,  Tommy D. Bennett

    IPC分类号： A61N1/00

    CPC分类号： A61N1/056 ,  A61N1/3611 ,  A61N1/36114

    摘要： A method includes controlling a cardiac pacing rate of an implantable medical device (IMD) to control a heart rate of a patient and determining that the patient is in a resting state. The method further includes modifying the pacing rate of the IMD for N cardiac cycles in response to determining that the patient is in the resting state. N is an integer greater than 1. Modifying the pacing rate includes incrementally increasing the pacing rate for a first portion of the N cardiac cycles, and incrementally decreasing the pacing rate for a second portion of the N cardiac cycles.

    摘要翻译： 一种方法包括控制可植入医疗装置（IMD）的心脏起搏速率以控制患者的心率并确定患者处于静止状态。 所述方法还包括响应于确定患者处于静止状态而修改IM心脏起搏速率的N个心动周期。 N是大于1的整数。修改起搏速率包括逐渐增加N个心动周期的第一部分的起搏速率，并逐渐降低N个心动周期的第二部分的起搏速率。