5-Oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase
    2.
    发明申请
    5-Oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase 失效
    作为c-fms激酶的抑制剂的5-氧代-5,8-二氢 - 吡啶并 - 嘧啶

    公开(公告)号:US20070060577A1

    公开(公告)日:2007-03-15

    申请号:US11519611

    申请日:2006-09-12

    CPC分类号: C07D471/04

    摘要: The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof, wherein: W, A, Y, Z, R101 and R200 are described in the specification.

    摘要翻译: 本发明通过提供c-fms激酶的有效抑制剂来解决当前对选择性和有效的蛋白酪氨酸激酶抑制剂的需要。 本发明涉及新的式I化合物或其溶剂合物,水合物,互变异构体或其药学上可接受的盐,其中:W,A,Y,Z,R 101和R 200 在说明书中描述。

    Substituted thiazolidinedione indazoles, indoles and benzotriazoles as estrogen-related receptor-α modulators
    3.
    发明授权
    Substituted thiazolidinedione indazoles, indoles and benzotriazoles as estrogen-related receptor-α modulators 有权
    取代的噻唑烷二酮吲唑,吲哚和苯并三唑作为雌激素相关受体α调节剂

    公开(公告)号:US08796256B2

    公开(公告)日:2014-08-05

    申请号:US13114084

    申请日:2011-05-24

    IPC分类号: C07D417/06

    CPC分类号: C07D417/06

    摘要: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondylitis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), bone-related diseases (including those related to bone formation), breast cancer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartilage degeneration, and those related to cartilage formation), chondrodysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, diabetes, disorders of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndrome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, osteolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.

    摘要翻译: 本发明涉及式(I)化合物,制备这些化合物的方法,组合物,中间体及其衍生物,用于治疗包括但不限于强直性脊柱炎,动脉粥样硬化,关节炎(如类风湿性关节炎,感染性关节炎,儿童期 关节炎,牛皮癣关节炎,反应性关节炎),骨相关疾病(包括与骨形成相关的疾病),乳腺癌(包括对抗雌激素治疗无反应的那些),心血管疾病,软骨相关疾病(如软骨损伤/损失, 软骨变性和与软骨形成相关的软骨变性,软骨发育不全,软骨肉瘤,慢性背部损伤,慢性支气管炎,慢性炎症性气道疾病,慢性阻塞性肺病,糖尿病,能量稳态障碍,痛风,假性血糖,脂质障碍,代谢综合征,多发性 骨髓瘤,肥胖症,骨关节炎,成骨不全,骨质溶解骨 骨质疏松症,骨质疏松症,佩吉特氏病,牙周病,风湿性多肌痛,莱特综合征,重复性应激损伤,高血糖,升高的血糖水平和胰岛素抵抗。

    5-Oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase
    4.
    发明申请
    5-Oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase 失效
    作为c-fms激酶的抑制剂的5-氧代-5,8-二氢 - 吡啶并 - 嘧啶

    公开(公告)号:US20070060578A1

    公开(公告)日:2007-03-15

    申请号:US11519662

    申请日:2006-09-12

    CPC分类号: C07D471/04

    摘要: The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof, wherein:W, A, Y, n, Z, and R102 are described in the specification.

    摘要翻译: 本发明通过提供c-fms激酶的有效抑制剂来解决当前对选择性和有效的蛋白酪氨酸激酶抑制剂的需要。 本发明涉及新的式I化合物或其溶剂化物,水合物,互变异构体或其药学上可接受的盐,其中:W,A,Y,n,Z和R 102描述于 规格。

    Liquid crystal grating module and two dimension-three dimension switchable liquid crystal display device using the same
    8.
    发明授权
    Liquid crystal grating module and two dimension-three dimension switchable liquid crystal display device using the same 有权
    液晶光栅模块和二维三维可切换液晶显示装置

    公开(公告)号:US09069216B2

    公开(公告)日:2015-06-30

    申请号:US13643445

    申请日:2010-11-09

    IPC分类号: G02F1/1343 G02B27/22

    摘要: A liquid crystal grating module (3) and a two dimension-three dimension switchable liquid crystal display device using the same. The liquid crystal grating module (3) comprises a first transparent electrode layer (20) and a second transparent electrode layer (50). The first transparent electrode layer (20) and the second transparent electrode layer (50) are provided with interval. The first transparent electrode layer (20) comprises a plurality of lateral electrode bars (202,204). The second transparent electrode layer (50) comprises a plurality of vertical electrode bars (502,504). The lateral electrode bars (202,204) and the vertical electrode bars (502,504) are alternately superposed on each other with interval to form a grating structure. The vertical electrode bars (502,504) have three different widths in the direction vertical to the liquid crystal display pixels.

    摘要翻译: 液晶光栅模块(3)和使用其的二维三维可切换液晶显示装置。 液晶光栅模块(3)包括第一透明电极层(20)和第二透明电极层(50)。 第一透明电极层(20)和第二透明电极层(50)间隔设置。 第一透明电极层(20)包括多个横向电极棒(202,204)。 第二透明电极层(50)包括多个垂直电极棒(502,504)。 横向电极棒(202,204)和垂直电极棒(502,504)以间隔彼此交替重叠以形成光栅结构。 垂直电极棒(502,504)在垂直于液晶显示像素的方向上具有三个不同的宽度。

    MOTOR AND ROTOR THEREOF
    9.
    发明申请
    MOTOR AND ROTOR THEREOF 有权
    电机和转子

    公开(公告)号:US20140175932A1

    公开(公告)日:2014-06-26

    申请号:US14235617

    申请日:2011-08-29

    IPC分类号: H02K1/27

    摘要: Disclosed are a motor and a rotor thereof. Taking the distance between the two endpoints of a permanent magnet (20) of a motor rotor that are on the side away from the centre of an iron core (10) as the length L of the permanent magnet, and the distance between a line connecting the two endpoints of the permanent magnet that are on the side away from the centre of the iron core (10) and the centre point on the side of the permanent magnet that is close to the centreline of the iron core as the width H of the permanent magnet, then H/L≧1/10. By adjusting the relationship between the length L and width H of the permanent magnet, the air gap magnetic density of the permanent magnet can be effectively increased, i.e. increasing the permanent magnetic flux of the rotor in the directions of the d axis and q axis. Hence, the utilization rate of the permanent magnet and the performance of the rotor can be improved without increasing the number of permanent magnets used.

    摘要翻译: 公开了一种电机及其转子。 将离开铁芯(10)的中心的一侧的电动机转子的永久磁铁(20)的两个端点之间的距离设为永久磁铁的长度L,以及连接线 远离铁芯(10)的中心的一侧的永久磁体的两个端点和永久磁体侧的中心点接近铁芯的中心线,作为 永磁体,H /L≥1/ 10。 通过调整永磁体的长度L和宽度H之间的关系,可以有效地增加永磁体的气隙磁密度,即增加转子在d轴和q轴方向上的永久磁通量。 因此,可以提高永久磁铁的利用率和转子的性能,而不增加使用的永磁体的数量。

    MOTOR ROTOR AND MOTOR HAVING SAME
    10.
    发明申请
    MOTOR ROTOR AND MOTOR HAVING SAME 审中-公开
    电机转子和电机

    公开(公告)号:US20140167550A1

    公开(公告)日:2014-06-19

    申请号:US14235611

    申请日:2011-08-29

    IPC分类号: H02K1/27

    摘要: Disclosed are a motor rotor and a motor having same, wherein the motor rotor comprises an iron core (10) and permanent magnets (20) provided within the iron core (10), sets of mounting grooves (30) are provided in the peripheral direction of the iron core, with each set of mounting grooves comprising more than two mounting grooves (30) arranged intermittently in the radial direction of the iron core (10). The permanent magnets (20) are correspondingly embedded into the individual mounting grooves (30). The thickness of the permanent magnet (20) at the centre of the cross section thereof and perpendicular to the rotor axis is greater than the thickness at both ends thereof. The rotor optimizes the shape of the permanent magnets (20) and improves the efficiency of the motor.

    摘要翻译: 公开了一种电动机转子和具有该电动机转子的电动机,其中,所述电动机转子包括设置在所述铁芯(10)内的铁芯(10)和永磁体(20),所述安装槽(30) 其中每组安装槽包括沿着铁芯(10)的径向方向间歇地设置的多于两个的安装槽(30)。 永磁体(20)相应地嵌入到各个安装槽(30)中。 永磁体(20)的横截面中心并且与转子轴线垂直的厚度大于其两端的厚度。 转子优化永磁体(20)的形状,提高电动机的效率。