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1.发明申请METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS 有权制备4-苯基-6-（2,2,2-三氟-1-苯基乙基）吡啶基化合物的方法公开(公告)号：US20110301349A1
公开(公告)日：2011-12-08
申请号：US13160678
申请日：2011-06-15
申请人： Mark S. Bednarz , Hugh Alfred Burgoon, JR. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
发明人： Mark S. Bednarz , Hugh Alfred Burgoon, JR. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
IPC分类号： C07D239/42 , C07D231/12
CPC分类号： C07D403/12 , C07D231/12
摘要： Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
摘要翻译： 公开了可用于制备式I化合物及其盐的方法。 还公开了可用于制备这些化合物的中间体。
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2.发明授权Methods of preparing 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds 有权制备4-苯基-6-（2,2,2-三氟-1-苯基乙氧基）嘧啶类化合物的方法公开(公告)号：US08575362B2
公开(公告)日：2013-11-05
申请号：US13160678
申请日：2011-06-15
申请人： Mark S. Bednarz , Hugh Alfred Burgoon, Jr. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
发明人： Mark S. Bednarz , Hugh Alfred Burgoon, Jr. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
IPC分类号： C07D231/12
CPC分类号： C07D403/12 , C07D231/12
摘要： Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
摘要翻译： 公开了可用于制备式I化合物及其盐的方法。 还公开了可用于制备这些化合物的中间体。
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公开(公告)号：US07968729B2
公开(公告)日：2011-06-28
申请号：US12732311
申请日：2010-03-26
申请人： Mark S. Bednarz , Hugh Alfred Burgoon, Jr. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
发明人： Mark S. Bednarz , Hugh Alfred Burgoon, Jr. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
IPC分类号： C07D231/10
CPC分类号： C07D403/12 , C07D231/12
摘要： Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
摘要翻译： 公开了可用于制备式I化合物及其盐的方法。 还公开了可用于制备这些化合物的中间体。
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4.发明申请METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS 审中-公开制备4-苯基-6-（2,2,2-三氟-1-苯基乙基）吡啶基化合物的方法公开(公告)号：US20090062540A1
公开(公告)日：2009-03-05
申请号：US12196341
申请日：2008-08-22
申请人： Mark S. Bednarz , Hugh Alfred Burgoon, JR. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
发明人： Mark S. Bednarz , Hugh Alfred Burgoon, JR. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
IPC分类号： C07D403/12 , C07D231/12
CPC分类号： C07D403/12 , C07D231/12
摘要： Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
摘要翻译： 公开了可用于制备式I化合物及其盐的方法。 还公开了可用于制备这些化合物的中间体。
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公开(公告)号：US20100240906A1
公开(公告)日：2010-09-23
申请号：US12732311
申请日：2010-03-26
申请人： Mark S. Bednarz , Hugh Alfred Burgoon, JR. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
发明人： Mark S. Bednarz , Hugh Alfred Burgoon, JR. , Shinya Iimura , Ramanaiah C. Kanamarlapudi , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang
IPC分类号： C07D233/60
CPC分类号： C07D403/12 , C07D231/12
摘要： Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
摘要翻译： 公开了可用于制备式I化合物及其盐的方法。 还公开了可用于制备这些化合物的中间体。
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公开(公告)号：US20090048280A1
公开(公告)日：2009-02-19
申请号：US11647517
申请日：2006-12-28
申请人： Hugh Alfred Burgoon, JR. , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang
发明人： Hugh Alfred Burgoon, JR. , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang
IPC分类号： A61K31/513 , C07D239/46
CPC分类号： A61K31/505 , C07D239/47
摘要： Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:
摘要翻译： 公开了用于制备取代的苯丙氨酸类化合物（例如式I）的中间体和合成方法：
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公开(公告)号：US07855291B2
公开(公告)日：2010-12-21
申请号：US11647517
申请日：2006-12-28
申请人： Hugh Alfred Burgoon, Jr. , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang
发明人： Hugh Alfred Burgoon, Jr. , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang
IPC分类号： C07D239/34 , C07D403/12 , A61K31/506 , A61K31/505 , A61P9/02
CPC分类号： A61K31/505 , C07D239/47
摘要： Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:
摘要翻译： 公开了用于制备取代的苯丙氨酸类化合物（例如式I）的中间体和合成方法：
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8.发明授权Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitors 有权用于制备钠葡萄糖共转运蛋白2抑制剂的方法和化合物公开(公告)号：US08026347B2
公开(公告)日：2011-09-27
申请号：US12174722
申请日：2008-07-17
申请人： Nicole Cathleen Goodwin , Bryce Alden Harrison , Shinya Iimura , Ross Mabon , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang , Matthew Mangzhu Zhao
发明人： Nicole Cathleen Goodwin , Bryce Alden Harrison , Shinya Iimura , Ross Mabon , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang , Matthew Mangzhu Zhao
摘要： Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula I:
摘要翻译： 公开了合成钠葡萄糖共转运蛋白2抑制剂的方法，以及其中有用的化合物。 特别的抑制剂是式I的化合物：
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9.发明授权Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitors 有权用于制备钠葡萄糖共转运蛋白2抑制剂的方法和化合物公开(公告)号：US08293878B2
公开(公告)日：2012-10-23
申请号：US13207576
申请日：2011-08-11
申请人： Nicole Cathleen Goodwin , Bryce Alden Harrison , Shinya Iimura , Ross Mabon , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang , Matthew Mangzhu Zhao
发明人： Nicole Cathleen Goodwin , Bryce Alden Harrison , Shinya Iimura , Ross Mabon , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang , Matthew Mangzhu Zhao
摘要： Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula I.
摘要翻译： 公开了合成钠葡萄糖共转运蛋白2抑制剂的方法，以及其中有用的化合物。 特别的抑制剂是式I的化合物。
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10.发明申请METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS 有权用于制备葡萄糖葡萄糖共转运剂2抑制剂的方法和化合物公开(公告)号：US20090030198A1
公开(公告)日：2009-01-29
申请号：US12174722
申请日：2008-07-17
申请人： Nicole Cathleen Goodwin , Bryce Alden Harrison , Shinya Iimura , Ross Mabon , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang , Matthew Mangzhu Zhao
发明人： Nicole Cathleen Goodwin , Bryce Alden Harrison , Shinya Iimura , Ross Mabon , Qiuling Song , Wenxue Wu , Jie Yan , Haiming Zhang , Matthew Mangzhu Zhao
IPC分类号： C07D413/06 , C07D315/00 , C07D493/04 , C07C43/225
摘要： Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula I:
摘要翻译： 公开了合成钠葡萄糖共转运蛋白2抑制剂的方法，以及其中有用的化合物。 特别的抑制剂是式I的化合物：
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