专利检索 ap:("Hugh Alfred Burgoon, Jr." OR "Ramanaiah C. Kanamarlapudi" OR "Iain Fraser Pickersgill" OR "Zhi-Cai Shi" OR "Wenxue Wu" OR "Haiming Zhang") AND inv:"Zhi-Cai Shi" 第 1 页

1.

发明申请
Process for the preparation of substituted phenylalanines 有权
标题翻译：制备取代苯丙氨酸的方法

公开(公告)号：US20090048280A1

公开(公告)日：2009-02-19

申请号：US11647517

申请日：2006-12-28

申请人： Hugh Alfred Burgoon, JR. , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang

发明人： Hugh Alfred Burgoon, JR. , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang

IPC分类号： A61K31/513 , C07D239/46

CPC分类号： A61K31/505 , C07D239/47

摘要： Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:

摘要翻译： 公开了用于制备取代的苯丙氨酸类化合物（例如式I）的中间体和合成方法：

2.

发明授权
Process for the preparation of substituted phenylalanines 有权
标题翻译：制备取代苯丙氨酸的方法

公开(公告)号：US07855291B2

公开(公告)日：2010-12-21

申请号：US11647517

申请日：2006-12-28

申请人： Hugh Alfred Burgoon, Jr. , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang

发明人： Hugh Alfred Burgoon, Jr. , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang

IPC分类号： C07D239/34 , C07D403/12 , A61K31/506 , A61K31/505 , A61P9/02

CPC分类号： A61K31/505 , C07D239/47

摘要： Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:

摘要翻译： 公开了用于制备取代的苯丙氨酸类化合物（例如式I）的中间体和合成方法：

3.

发明授权
Compounds useful in the preparation of tryptophan hydroxylase inhibitors 有权
标题翻译：可用于制备色氨酸羟化酶抑制剂的化合物

公开(公告)号：US08450532B2

公开(公告)日：2013-05-28

申请号：US13024469

申请日：2011-02-10

申请人： Hugh Alfred Burgoon , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang , Matthew Mangzhu Zhao

发明人： Hugh Alfred Burgoon , Ramanaiah C. Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang , Matthew Mangzhu Zhao

IPC分类号： C07C33/34 , C07C43/205

CPC分类号： A61K31/505 , C07C43/23 , C07D239/42 , C07D239/47 , C07D239/48

摘要： Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:

摘要翻译： 公开了用于制备取代的苯丙氨酸类化合物（例如式I）的中间体和合成方法：

4.

发明申请
COMPOUNDS USEFUL IN THE PREPARATION OF TRYPTOPHAN HYDRROXYLASE INHIBITORS 有权
标题翻译：化合物在制备TRYPTOPHAN HYDRXYLASE抑制剂中有用

公开(公告)号：US20110130564A1

公开(公告)日：2011-06-02

申请号：US13024469

申请日：2011-02-10

申请人： Hugh Alfred Burgoon , Ramanaiah Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang , Matthew Mangzhu Zhao

发明人： Hugh Alfred Burgoon , Ramanaiah Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang , Matthew Mangzhu Zhao

IPC分类号： C07D239/47 , C07C43/23

CPC分类号： A61K31/505 , C07C43/23 , C07D239/42 , C07D239/47 , C07D239/48

摘要： Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:

摘要翻译： 公开了用于制备取代的苯丙氨酸类化合物（例如式I）的中间体和合成方法：

5.

发明授权
Process for the preparation of substituted phenylalanines 有权
标题翻译：制备取代苯丙氨酸的方法

公开(公告)号：US07897763B2

公开(公告)日：2011-03-01

申请号：US12257558

申请日：2008-10-24

申请人： Hugh Alfred Burgoon , Ramanaiah Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang , Matthew Mangzhu Zhao

发明人： Hugh Alfred Burgoon , Ramanaiah Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang , Matthew Mangzhu Zhao

IPC分类号： C07D239/42 , C07D403/12 , A61K31/506 , A61P9/02

CPC分类号： A61K31/505 , C07C43/23 , C07D239/42 , C07D239/47 , C07D239/48

摘要： Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:

摘要翻译： 公开了用于制备取代的苯丙氨酸类化合物（例如式I）的中间体和合成方法：

6.

发明申请
PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLALANINES 有权
标题翻译：制备取代的苯乙烯胺的方法

公开(公告)号：US20090118505A1

公开(公告)日：2009-05-07

申请号：US12257558

申请日：2008-10-24

申请人： Hugh Alfred Burgoon , Ramanaiah Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang , Matthew Mangzhu Zhao

发明人： Hugh Alfred Burgoon , Ramanaiah Kanamarlapudi , Iain Fraser Pickersgill , Zhi-Cai Shi , Wenxue Wu , Haiming Zhang , Matthew Mangzhu Zhao

IPC分类号： C07D239/47 , C07D239/42 , C07C43/23

CPC分类号： A61K31/505 , C07C43/23 , C07D239/42 , C07D239/47 , C07D239/48

摘要： Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:

摘要翻译： 公开了用于制备取代的苯丙氨酸类化合物（例如式I）的中间体和合成方法：

7.

发明申请
Multicyclic amino acid derivatives and methods of their use 有权
标题翻译：多环氨基酸衍生物及其使用方法

公开(公告)号：US20070191370A1

公开(公告)日：2007-08-16

申请号：US11638677

申请日：2006-12-12

申请人： Arokiasamy Devasagayaraj , Haihong Jin , Qingyun Liu , Brett Marinelli , Lakshama Samala , Zhi-Cai Shi , Ashok Tunoori , Ying Wang , Wenxue Wu , Chengmin Zhang , Haiming Zhang

发明人： Arokiasamy Devasagayaraj , Haihong Jin , Qingyun Liu , Brett Marinelli , Lakshama Samala , Zhi-Cai Shi , Ashok Tunoori , Ying Wang , Wenxue Wu , Chengmin Zhang , Haiming Zhang

IPC分类号： A61K31/53 , A61K31/506 , A61K31/501 , A61K31/4965 , A61K31/497 , A61K31/4439 , C07D403/02

CPC分类号： C07D251/18 , C07B2200/07 , C07C229/36 , C07C229/42 , C07C229/44 , C07C275/42 , C07C311/29 , C07C2601/08 , C07D213/74 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/48 , C07D241/20 , C07D241/24 , C07D249/06 , C07D251/16 , C07D251/22 , C07D251/52 , C07D401/04 , C07D403/04 , C07D403/12 , C07D409/04 , C07D409/12 , C07D413/12

摘要： Compounds of formulae I and II are disclosed, as well as compositions comprising them and methods of their use to treat, prevent and manage serotonin-mediated diseases and disorders:

摘要翻译： 公开了式I和II的化合物，以及包含它们的组合物及其用于治疗，预防和控制5-羟色胺介导的疾病和障碍的方法：

8.

发明申请
TRYPTOPHAN HYDROXYLASE INHIBITORS 有权
标题翻译： TRYPTOPHAN羟基酶抑制剂

公开(公告)号：US20120157484A1

公开(公告)日：2012-06-21

申请号：US13290261

申请日：2011-11-07

申请人： Arokiasamy DEVASAGAYARAJ , Haihong Jin , Qingyun Liu , Brett Marinelli , Lakshama Samala , Zhi-Cai Shi , Ashok Tunoori , Ying Wang , Wenxue Wu , Chengmin Zhang , Haiming Zhang

发明人： Arokiasamy DEVASAGAYARAJ , Haihong Jin , Qingyun Liu , Brett Marinelli , Lakshama Samala , Zhi-Cai Shi , Ashok Tunoori , Ying Wang , Wenxue Wu , Chengmin Zhang , Haiming Zhang

IPC分类号： A61K31/505 , A61P1/00 , C07D401/04 , A61K31/506 , C07D239/47 , C07D239/42

CPC分类号： C07D251/18 , C07B2200/07 , C07C229/36 , C07C229/42 , C07C229/44 , C07C275/42 , C07C311/29 , C07C2601/08 , C07D213/74 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/48 , C07D241/20 , C07D241/24 , C07D249/06 , C07D251/16 , C07D251/22 , C07D251/52 , C07D401/04 , C07D403/04 , C07D403/12 , C07D409/04 , C07D409/12 , C07D413/12

摘要： Compounds of formulae I and II are disclosed, as well as compositions comprising them and methods of their use to treat, prevent and manage serotonin-mediated diseases and disorders:

摘要翻译： 公开了式I和II的化合物，以及包含它们的组合物及其用于治疗，预防和控制5-羟色胺介导的疾病和障碍的方法：

9.

发明授权
Tryptophan hydroxylase inhibitors 有权
标题翻译：色氨酸羟化酶抑制剂

公开(公告)号：US08629156B2

公开(公告)日：2014-01-14

申请号：US13290261

申请日：2011-11-07

申请人： Arokiasamy Devasagayaraj , Haihong Jin , Qingyun Liu , Brett Marinelli , Lakshama Samala , Zhi-Cai Shi , Ashok Tunoori , Ying Wang , Wenxue Wu , Chengmin Zhang , Haiming Zhang

发明人： Arokiasamy Devasagayaraj , Haihong Jin , Qingyun Liu , Brett Marinelli , Lakshama Samala , Zhi-Cai Shi , Ashok Tunoori , Ying Wang , Wenxue Wu , Chengmin Zhang , Haiming Zhang

IPC分类号： C07C229/36 , C07C229/42 , C07C229/44 , C07C275/42 , C07C311/29 , C07D213/74 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/48 , C07D241/20 , C07D241/24 , C07D249/06 , C07D251/16 , C07D251/18 , C07D251/22 , C07D251/52 , C07D401/04 , C07D403/04 , C07D403/12 , C07D409/04 , C07D409/12 , C07D413/12 , A61K31/505 , A61P1/00

CPC分类号： C07D251/18 , C07B2200/07 , C07C229/36 , C07C229/42 , C07C229/44 , C07C275/42 , C07C311/29 , C07C2601/08 , C07D213/74 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/48 , C07D241/20 , C07D241/24 , C07D249/06 , C07D251/16 , C07D251/22 , C07D251/52 , C07D401/04 , C07D403/04 , C07D403/12 , C07D409/04 , C07D409/12 , C07D413/12

摘要： Compounds of formulae I and II are disclosed, as well as compositions comprising them and methods of their use to treat, prevent and manage serotonin-mediated diseases and disorders:

摘要翻译： 公开了式I和II的化合物，以及包含它们的组合物及其用于治疗，预防和控制5-羟色胺介导的疾病和障碍的方法：

10.

发明申请
MULTICYCLIC AMINO ACID DERIVATIVES AND METHODS OF THEIR USE 有权
标题翻译：多种氨基酸衍生物及其使用方法

公开(公告)号：US20100280054A1

公开(公告)日：2010-11-04

申请号：US12750278

申请日：2010-03-30

申请人： Arokiasamy Devasagayaraj , Haihong Jin , Qingyun Liu , Brett Marinelli , Lakshama Samala , Zhi-Cai Shi , Ashok Tunoori , Ying Wang , Wenxue Wu , Chengmin Zhang , Haiming Zhang

发明人： Arokiasamy Devasagayaraj , Haihong Jin , Qingyun Liu , Brett Marinelli , Lakshama Samala , Zhi-Cai Shi , Ashok Tunoori , Ying Wang , Wenxue Wu , Chengmin Zhang , Haiming Zhang

IPC分类号： A61K31/505 , C07D239/47 , A61P1/00

CPC分类号： C07D251/18 , C07B2200/07 , C07C229/36 , C07C229/42 , C07C229/44 , C07C275/42 , C07C311/29 , C07C2601/08 , C07D213/74 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/48 , C07D241/20 , C07D241/24 , C07D249/06 , C07D251/16 , C07D251/22 , C07D251/52 , C07D401/04 , C07D403/04 , C07D403/12 , C07D409/04 , C07D409/12 , C07D413/12

摘要： Compounds of formulae I and II are disclosed, as well as compositions comprising them and methods of their use to treat, prevent and manage serotonin-mediated diseases and disorders:

摘要翻译： 公开了式I和II的化合物，以及包含它们的组合物及其用于治疗，预防和控制5-羟色胺介导的疾病和障碍的方法：