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公开(公告)号：US07442190B2
公开(公告)日：2008-10-28
申请号：US11129205
申请日：2005-05-13
CPC分类号： A61B5/6885 , A61B5/053 , A61B5/0538 , A61B5/6886 , A61B18/02 , A61B2017/00026 , A61B2017/00039 , A61B2017/00084 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61B2090/065
摘要： A method and system for determining contact assessment includes the steps of positioning a catheter at a tissue treatment site, where the catheter has a proximal end portion and a distal end portion, the proximal end portion defining at least one fluid inlet port and at least one fluid outlet port, an expandable membrane defining a cooling chamber a coolant injection lumen in fluid communication with the at least one fluid inlet port and the cooling chamber, a coolant return lumen in fluid communication with the at least one fluid outlet port and the cooling chamber, the coolant injection tube, the cooling chamber, and the primary coolant return lumen defining a fluid pathway and a temperature sensor located near the coolant return lumen; measuring an internal temperature of the chamber, and modifying the position of the catheter in response to the measured temperature. The method and system can also use a measured impedance to determine contact assessment.
摘要翻译： 用于确定接触评估的方法和系统包括将导管定位在组织治疗部位的步骤，其中所述导管具有近端部分和远端部分，所述近端部分限定至少一个流体入口端口和至少一个 流体出口端口，限定冷却室的可膨胀膜，与所述至少一个流体入口和所述冷却室流体连通的冷却剂注入腔，与所述至少一个流体出口和所述冷却室流体连通的冷却剂返回内腔 冷却剂注入管，冷却室和第一冷却剂回流腔限定流体通路和位于冷却剂回流腔附近的温度传感器; 测量腔室的内部温度，以及响应于测量的温度改变导管的位置。 该方法和系统还可以使用测量的阻抗来确定接触评估。
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公开(公告)号：US08771264B2
公开(公告)日：2014-07-08
申请号：US12245176
申请日：2008-10-03
IPC分类号： A61B18/02
CPC分类号： A61B5/6885 , A61B5/053 , A61B5/0538 , A61B5/6886 , A61B18/02 , A61B2017/00026 , A61B2017/00039 , A61B2017/00084 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61B2090/065
摘要： A medical apparatus and system for determining contact assessment includes a catheter having an elongate body having a proximal end, a distal end opposite the proximal end, and defining an injection lumen and an exhaust lumen, an expandable membrane defining a cooling chamber disposed at a point along the elongate body, the cooling chamber in fluid communication with the injection lumen and the exhaust lumen, and a contact assessment element which may be a temperature sensor located proximate the coolant return lumen for measuring an internal temperature of the chamber. The system may include the catheter, a console having a fluid supply, an exhaust path and at least one control mechanism operationally coupled to the temperature sensor for processing a temperature signal received from the temperature sensor. The apparatus and system can also have multiple electrodes to measure and process various impedances to determine contact assessment.
摘要翻译： 用于确定接触评估的医疗装置和系统包括具有细长主体的导管，所述细长主体具有近端，与近端相对的远端，并且限定注射腔和排气腔，限定设置在一点的冷却室的可扩张膜 沿着细长体，与注射腔和排气腔流体连通的冷却室和接触评估元件，其可以是靠近冷却剂返回腔的温度传感器，用于测量腔室的内部温度。 该系统可以包括导管，具有流体供应的控制台，排气路径和可操作地耦合到温度传感器的至少一个控制机构，用于处理从温度传感器接收的温度信号。 该装置和系统还可以具有多个电极来测量和处理各种阻抗以确定接触评估。
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公开(公告)号：US20090030288A1
公开(公告)日：2009-01-29
申请号：US12245176
申请日：2008-10-03
CPC分类号： A61B5/6885 , A61B5/053 , A61B5/0538 , A61B5/6886 , A61B18/02 , A61B2017/00026 , A61B2017/00039 , A61B2017/00084 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61B2090/065
摘要： A medical apparatus and system for determining contact assessment includes a catheter having an elongate body having a proximal end, a distal end opposite the proximal end, and defining an injection lumen and an exhaust lumen, an expandable membrane defining a cooling chamber disposed at a point along the elongate body, the cooling chamber in fluid communication with the injection lumen and the exhaust lumen, and a contact assessment element which may be a temperature sensor located proximate the coolant return lumen for measuring an internal temperature of the chamber. The system may include the catheter, a console having a fluid supply, an exhaust path and at least one control mechanism operationally coupled to the temperature sensor for processing a temperature signal received from the temperature sensor. The apparatus and system can also have multiple electrodes to measure and process various impedances to determine contact assessment.
摘要翻译： 用于确定接触评估的医疗装置和系统包括具有细长主体的导管，所述细长主体具有近端，与近端相对的远端，并且限定注射腔和排气腔，限定设置在一点的冷却室的可扩张膜 沿着细长体，与注射腔和排气腔流体连通的冷却室和接触评估元件，其可以是靠近冷却剂返回腔的温度传感器，用于测量腔室的内部温度。 该系统可以包括导管，具有流体供应的控制台，排气路径和可操作地耦合到温度传感器的至少一个控制机构，用于处理从温度传感器接收的温度信号。 该装置和系统还可以具有多个电极来测量和处理各种阻抗以确定接触评估。
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公开(公告)号：US08696656B2
公开(公告)日：2014-04-15
申请号：US12355883
申请日：2009-01-19
申请人： Marwan Abboud , Johnny Al Asmar , Chadi Harmouche
发明人： Marwan Abboud , Johnny Al Asmar , Chadi Harmouche
IPC分类号： A61B18/02
CPC分类号： A61B18/00 , A61B5/0537 , A61B5/0538 , A61B5/0809 , A61B18/02 , A61B18/1492 , A61B2017/00026 , A61B2017/22051 , A61B2018/0022 , A61B2018/00702 , A61B2018/00875 , A61B2018/0212
摘要： A method of treating tissue is provided, including positioning a portion of a catheter in proximity to cardiac tissue; measuring an impedance value with the catheter; determining a respiratory rate based at least in part on the measured impedance value; and thermally treating the cardiac tissue with the catheter.
摘要翻译： 提供一种治疗组织的方法，包括将导管的一部分定位在心脏组织附近; 用导管测量阻抗值; 至少部分地基于所测量的阻抗值确定呼吸频率; 并用导管热心处理心脏组织。
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公开(公告)号：US07842031B2
公开(公告)日：2010-11-30
申请号：US11283057
申请日：2005-11-18
申请人： Marwan Abboud , Johnny Al Asmar , Chadi Harmouche
发明人： Marwan Abboud , Johnny Al Asmar , Chadi Harmouche
CPC分类号： A61B5/0537 , A61B18/02 , A61B2017/00026 , A61B2018/0022 , A61B2018/0212
摘要： Methods and systems for detecting fluid egress, assessing lesion quality, determining tissue composition or structure, determining ice coverage of catheter tip and providing tissue contact assessment, by providing a catheter having a shaft with a proximal end portion and a distal end portion, the proximal end portion and the distal end portion define at least one fluid pathway therebetween with the shaft having a plurality of electrodes, positioning the catheter at a tissue treatment site, applying an electrical current between at least two of the plurality of electrodes, measuring impedance voltage between the at least two of the plurality of electrodes and, processing the measured impedance voltage caused by the applied electrical current to determine if fluid egress is present, to assess lesion quality, to determine tissue composition, ice cover of catheter tip, and to provide contact assessment. The system may have a control unit, a microprocessor, an impedance measuring device or the like to perform processing of impedance data.
摘要翻译： 用于检测流体出口的方法和系统，评估病变质量，确定组织组成或结构，通过提供具有近端部分和远端部分的轴的导管，确定导管尖端的冰覆盖和提供组织接触评估， 末端部分和远端部分限定其间的至少一个流体通路，其中轴具有多个电极，将导管定位在组织治疗部位，在多个电极中的至少两个之间施加电流，测量多个电极之间的阻抗电压 所述多个电极中的至少两个，并且处理由施加的电流引起的测量的阻抗电压以确定是否存在流体出口，以评估病变质量，确定组织组成，导管尖端的冰盖，并提供接触 评定。 系统可以具有控制单元，微处理器，阻抗测量装置等，以执行阻抗数据的处理。
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公开(公告)号：US20080200829A1
公开(公告)日：2008-08-21
申请号：US12109942
申请日：2008-04-25
申请人： Marwan Abboud , Johnny Al Asmar , Chadi Harmouche
发明人： Marwan Abboud , Johnny Al Asmar , Chadi Harmouche
CPC分类号： A61B5/0537 , A61B18/02 , A61B2017/00026 , A61B2018/0022 , A61B2018/0212
摘要： Methods and systems for detecting fluid egress, assessing lesion quality, determining tissue composition or structure, determining ice coverage of catheter tip and providing tissue contact assessment, by providing a catheter having a shaft with a proximal end portion and a distal end portion, the proximal end portion and the distal end portion define at least one fluid pathway therebetween with the shaft having a plurality of electrodes, positioning the catheter at a tissue treatment site, applying an electrical current between at least two of the plurality of electrodes, measuring impedance voltage between the at least two of the plurality of electrodes and, processing the measured impedance voltage caused by the applied electrical current to determine if fluid egress is present, to assess lesion quality, to determine tissue composition, ice cover of catheter tip, and to provide contact assessment. The system may have a control unit, a microprocessor, an impedance measuring device or the like to perform processing of impedance data.
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公开(公告)号：US07914525B2
公开(公告)日：2011-03-29
申请号：US12109942
申请日：2008-04-25
申请人： Marwan Abboud , Johnny Al Asmar , Chadi Harmouche
发明人： Marwan Abboud , Johnny Al Asmar , Chadi Harmouche
CPC分类号： A61B5/0537 , A61B18/02 , A61B2017/00026 , A61B2018/0022 , A61B2018/0212
摘要： Methods and systems for detecting fluid egress, assessing lesion quality, determining tissue composition or structure, determining ice coverage of catheter tip and providing tissue contact assessment, by providing a catheter having a shaft with a proximal end portion and a distal end portion, the proximal end portion and the distal end portion define at least one fluid pathway therebetween with the shaft having a plurality of electrodes, positioning the catheter at a tissue treatment site, applying an electrical current between at least two of the plurality of electrodes, measuring impedance voltage between the at least two of the plurality of electrodes and, processing the measured impedance voltage caused by the applied electrical current to determine if fluid egress is present, to assess lesion quality, to determine tissue composition, ice cover of catheter tip, and to provide contact assessment. The system may have a control unit, a microprocessor, an impedance measuring device or the like to perform processing of impedance data.
摘要翻译： 用于检测流体出口的方法和系统，评估病变质量，确定组织组成或结构，通过提供具有近端部分和远端部分的轴的导管，确定导管尖端的冰覆盖和提供组织接触评估， 末端部分和远端部分限定其间的至少一个流体通路，其中轴具有多个电极，将导管定位在组织治疗部位，在多个电极中的至少两个之间施加电流，测量多个电极之间的阻抗电压 所述多个电极中的至少两个，并且处理由施加的电流引起的测量的阻抗电压以确定是否存在流体出口，以评估病变质量，确定组织组成，导管尖端的冰盖，并提供接触 评定。 系统可以具有控制单元，微处理器，阻抗测量装置等，以执行阻抗数据的处理。
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公开(公告)号：US06575966B2
公开(公告)日：2003-06-10
申请号：US09945319
申请日：2001-08-31
申请人： Miriam Lane , Leonilda Capuano , David Holtan , Jean-Pierre Lalonde , Claudia Lückge , Jean-Luc Pageard , Marwan Abboud , Johnny Al Asmar , Abderrahim Benrabah , Ken Chen , John W. Lehmann , Philippe Marchand , Robert Martin , Fredric L. Milder , Daniel Nahon
发明人： Miriam Lane , Leonilda Capuano , David Holtan , Jean-Pierre Lalonde , Claudia Lückge , Jean-Luc Pageard , Marwan Abboud , Johnny Al Asmar , Abderrahim Benrabah , Ken Chen , John W. Lehmann , Philippe Marchand , Robert Martin , Fredric L. Milder , Daniel Nahon
IPC分类号： A61B1818
CPC分类号： A61B18/02 , A61B2017/22001 , A61B2017/22051 , A61B2017/22054 , A61B2017/22069 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要： An elongated catheter device with a distal balloon assembly is adapted for endovascular insertion. Coolant injected through the device may, in different embodiments, directly cool tissue contacting the balloon, or may cool a separate internal chamber. In the first case, the coolant also inflates the balloon, and spent coolant is returned to the handle via a return passage extending through the body of the catheter. Plural balloons may be provided, wherein a secondary outer balloon surrounds a primary inner balloon, the primary balloon being filled with coolant and acting as the cooling chamber, the secondary balloon being coupled to a vacuum return lumen to serve as a robust leak containment device and thermal insulator around the cooling chamber. Various configurations, such as surface modification of the balloon interface, or placement of particles, coatings, or expandable meshes or coils in the balloon interface, may be employed to achieve this function.
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公开(公告)号：US06761714B2
公开(公告)日：2004-07-13
申请号：US10124560
申请日：2002-04-17
申请人： Marwan Abboud , Johnny Al Asmar , John W. Lehmann
发明人： Marwan Abboud , Johnny Al Asmar , John W. Lehmann
IPC分类号： A61B1818
CPC分类号： A61B18/02 , A61B2017/00092 , A61B2017/00119 , A61B2018/0212 , A61B2018/0262 , A61F7/12
摘要： A surgical device includes a device body defining a sealed fluid path having a first end and a second end, a refrigerant supply in communication with the first end of the sealed fluid path; and a vacuum source in communication with the second end of the sealed fluid path. Leak detection apparatus can be provided in communication with the sealed fluid path.
摘要翻译： 手术装置包括限定具有第一端和第二端的密封流体路径的装置主体，与密封流体路径的第一端连通的制冷剂供应; 以及与密封流体路径的第二端连通的真空源。 泄漏检测装置可以与密封流体通道连通。
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公开(公告)号：US07300433B2
公开(公告)日：2007-11-27
申请号：US10397619
申请日：2003-03-26
申请人： Miriam Lane , Leonilda Capuano , David Holtan , Jean-Pierre Lalonde , Claudia Lückge , Jean-Luc Pageard , Marwan Abboud , Johnny Al Asmar , Abderrahim Benrabah , Ken Chen , John W. Lehmann , Philippe Marchand , Robert Martin , Fredric L. Milder , Daniel Nahon
发明人： Miriam Lane , Leonilda Capuano , David Holtan , Jean-Pierre Lalonde , Claudia Lückge , Jean-Luc Pageard , Marwan Abboud , Johnny Al Asmar , Abderrahim Benrabah , Ken Chen , John W. Lehmann , Philippe Marchand , Robert Martin , Fredric L. Milder , Daniel Nahon
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2017/22001 , A61B2017/22051 , A61B2017/22054 , A61B2017/22069 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要： An elongated catheter device with a distal balloon assembly is adapted for endovascular insertion. Coolant injected through the device may, in different embodiments, directly cool tissue contacting the balloon, or may cool a separate internal chamber. In the first case, the coolant also inflates the balloon, and spent coolant is returned to the handle via a return passage extending through the body of the catheter. Plural balloons may be provided, wherein a secondary outer balloon surrounds a primary inner balloon, the primary balloon being filled with coolant and acting as the cooling chamber, the secondary balloon being coupled to a vacuum return lumen to serve as a robust leak containment device and thermal insulator around the cooling chamber. Various configurations, such as surface modification of the balloon interface, or placement of particles, coatings, or expandable meshes or coils in the balloon interface, may be employed to achieve this function.
摘要翻译： 具有远端球囊组件的细长导管装置适于血管内插入。 在不同的实施例中，通过装置注入的冷却剂可以直接冷却接触气囊的组织，或者可以冷却单独的内部腔室。 在第一种情况下，冷却剂还使气囊膨胀，并且废弃的冷却剂经由延伸穿过导管主体的返回通道返回到手柄。 可以提供多个气球，其中次级外球囊围绕主内球囊，主气球填充有冷却剂并用作冷却室，次级球囊联接到真空返回腔以用作鲁棒的泄漏容纳装置， 冷却室周围的绝热体。 可以采用各种构造，例如球囊界面的表面改性，或者在气球界面中放置颗粒，涂层或可膨胀的网孔或线圈，以实现该功能。
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