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公开(公告)号:US20070179173A1
公开(公告)日:2007-08-02
申请号:US10582014
申请日:2005-09-26
申请人: Takeshi Kuroda , Takahito Yamauchi , Tomoichi Shinohara , Kunio Oshima , Chiharu Kitajima , Hitoshi Nagao , Tae Fukushima , Takahiro Tomoyasu , Hironobu Ishiyama , Kazuhide Ohta , Masaaki Takano , Takumi Sumida
发明人: Takeshi Kuroda , Takahito Yamauchi , Tomoichi Shinohara , Kunio Oshima , Chiharu Kitajima , Hitoshi Nagao , Tae Fukushima , Takahiro Tomoyasu , Hironobu Ishiyama , Kazuhide Ohta , Masaaki Takano , Takumi Sumida
IPC分类号: A61K31/473 , A61K31/4709 , C07D417/14
CPC分类号: C07D471/08 , C07D417/04 , C07D417/06 , C07D417/14 , C07D487/04 , C07D495/04
摘要: The present invention provides a carbostyril compound represented by General Formula (1) or a salt thereof, wherein A is a direct bond, a lower alkylene group, or a lower alkylidene group; X is an oxygen atom or a sulfur atom; R4 and R5 each represent a hydrogen atom; the bond between the 3 and 4 positions of the carbostyril skeleton is a single bond or a double bond; R1 is a hydrogen atom, etc; R2 is a hydrogen atom, etc; and R3 is a hydrogen atom, etc. The carbostyril compound or salt thereof of the present invention induces the production of TFF, and thus is usable for the treatment and/or prevention of disorders such as alimentary tract diseases, oral diseases, upper respiratory tract diseases, respiratory tract diseases, eye diseases, cancers, and wounds.
摘要翻译: 本发明提供由通式(1)表示的喹诺酮化合物或其盐,其中A为直接键,低级亚烷基或低级亚烷基; X是氧原子或硫原子; R 4和R 5各自表示氢原子; 喹诺酮骨架的3和4位之间的键是单键或双键; R 1是氢原子等; R 2是氢原子等; 和R 3是氢原子等。本发明的喹诺酮化合物或其盐诱导TFF的产生,因此可用于治疗和/或预防诸如消化道 疾病,口腔疾病,上呼吸道疾病,呼吸道疾病,眼睛疾病,癌症和伤口。
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公开(公告)号:US4246430A
公开(公告)日:1981-01-20
申请号:US967143
申请日:1978-12-06
申请人: Masaaki Takano , Masahiro Nakashima
发明人: Masaaki Takano , Masahiro Nakashima
CPC分类号: C07C51/43
摘要: A method for producing crystals of sorbic acid by recrystallization with an aqueous solution of an alcohol and wherein an alkali metal ion is employed as a crystal-modifying ion.According to this method, a recrystallized product of sorbic acid having a superior hardness, bulk density, fluidity, etc. is obtained.
摘要翻译: 通过用醇水溶液重结晶制备山梨酸晶体的方法,其中使用碱金属离子作为结晶修饰离子。 根据该方法,得到具有优异的硬度,体积密度,流动性等的山梨酸的再结晶物。
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公开(公告)号:US09504968B2
公开(公告)日:2016-11-29
申请号:US13822178
申请日:2011-09-07
申请人: Masaaki Takano
发明人: Masaaki Takano
CPC分类号: B01F3/04241 , E03C1/084 , Y02A20/411
摘要: The present invention provides a foamed-water generating aerator which is capable of generating good-quality foamed water containing fine, homogeneously distributed air bubbles. The foamed-water generating aerator (100) is fitted to a water discharge pipe to turn water being discharged into foamed water. A circumferential water flow curtain forming portion (110) includes a gap (111), through which water flows, and forms a three-dimensional circulating water flow curtain (112) in which an accelerated water-flow issuing downstream from the gap (111) is continuous in the circumferential direction. An air cavity (120) is provided at some intermediate point in a water-flow path as a place for forming the circulating water flow curtain (112) and sustains an air-filled condition even when a water-flow of the circulating water flow curtain enters therein. Air is drawn through an air ventilation hole (140) into an enclosed space, the enclosed space being defined by the circulating water flow curtain (112) formed in the air cavity (120) and a surrounding wall surface, is mixed with the circulating water flow curtain (112) to thereby form the foamed water.
摘要翻译: 本发明提供一种能够产生含有精细,均匀分布的气泡的优质发泡水的泡沫水发生曝气机。 发泡发生曝气器(100)安装在排水管上,将排放到发泡水中的水排出。 周向水流幕形成部分(110)包括间隙(111),水流过该间隙,并形成三维循环水流帘(112),其中在间隙(111)下游发出加速的水流, 在圆周方向上是连续的。 空气腔(120)设置在水流路径的某个中间点处,作为形成循环水流帘(112)的位置,并且即使在循环水流帘的水流时也保持充满气 进入。 空气通过空气通风孔140被吸入封闭空间,由形成在空气腔120中的循环水流帘112和周围壁面所限定的封闭空间与循环水 流动帘(112),从而形成发泡水。
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公开(公告)号:US08362252B2
公开(公告)日:2013-01-29
申请号:US12611921
申请日:2009-11-03
申请人: Takeshi Kuroda , Takahito Yamauchi , Tomoichi Shinohara , Kunio Oshima , Chiharu Kitajima , Hitoshi Nagao , Tae Fukushima , Takahiro Tomoyasu , Hironobu Ishiyama , Kazuhide Ohta , Masaaki Takano , Takumi Sumida
发明人: Takeshi Kuroda , Takahito Yamauchi , Tomoichi Shinohara , Kunio Oshima , Chiharu Kitajima , Hitoshi Nagao , Tae Fukushima , Takahiro Tomoyasu , Hironobu Ishiyama , Kazuhide Ohta , Masaaki Takano , Takumi Sumida
IPC分类号: C07D215/38
CPC分类号: C07D471/08 , C07D417/04 , C07D417/06 , C07D417/14 , C07D487/04 , C07D495/04
摘要: The present invention provides a carbostyril compound represented by General Formula (1) or a salt thereof, wherein A is a direct bond, a lower alkylene group, or a lower alkylidene group; X is an oxygen atom or a sulfur atom; R4 and R5 each represent a hydrogen atom; the bond between the 3 and 4 positions of the carbostyril skeleton is a single bond or a double bond; R1 is a hydrogen atom, etc; R2 is a hydrogen atom, etc; and R3 is a hydrogen atom, etc. The carbostyril compound or salt thereof of the present invention induces the production of TFF, and thus is usable for the treatment and/or prevention of disorders such as alimentary tract diseases, oral diseases, upper respiratory tract diseases, respiratory tract diseases, eye diseases, cancers, and wounds.
摘要翻译: 本发明提供由通式(1)表示的喹诺酮化合物或其盐,其中A为直接键,低级亚烷基或低级亚烷基; X是氧原子或硫原子; R4和R5各自表示氢原子; 喹诺酮骨架的3和4位之间的键是单键或双键; R1是氢原子等; R2是氢原子等; R3是氢原子等。本发明的喹诺酮化合物或其盐诱导TFF的产生,因此可用于治疗和/或预防诸如消化道疾病,口腔疾病,上呼吸道疾病 疾病,呼吸道疾病,眼睛疾病,癌症和伤口。
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公开(公告)号:US20110215175A1
公开(公告)日:2011-09-08
申请号:US13127154
申请日:2008-10-31
申请人: Masaaki Takano
发明人: Masaaki Takano
IPC分类号: E03C1/08
CPC分类号: E03C1/084 , B05B7/0425 , B05B15/65 , Y02A20/411
摘要: The present invention provides a water saving aerator that can reduce the amount of water flow and generate bubble foam water from water provided by the water delivery apparatus such as a water tap. The water saving aerator comprises a water saving disc 10 for controlling the amount of water from the water tap 200, having the through-hole 11 whose diameter is smaller than that of the water tap 200, so the water flow is injected by covering the opening of the water tap 200. A first cylinder 30 covering a diffuser object 20 is provided and a second cylinder 40 covering the first cylinder 30 is provided. The water injected from the through-hole 11 of the water saving disc 10 is diffused by the diffuser object 20, and the diffused water is received by the inner wall of the first cylinder 30. An air intake hole 33 is formed on the upper portion of the first cylinder 30, and when the air pressure of the first cylinder 30 is decreased by the water flow running into the water pass 71 between the diffuser object 20 and the first cylinder 30, the outer air is ventilated through the ventilation pass 72 formed between the first cylinder 30 and the second cylinder 40 via the air intake hole 33, the bubble form water is generated by mixing the water flow and air.
摘要翻译: 本发明提供一种节水曝气器,其可以减少水流量,并且由诸如水龙头的输水装置提供的水产生泡沫泡沫水。 节水充气机包括一个用于控制来自水龙头200的水量的节水盘10,其具有直径小于水龙头200直径的通孔11,因此水流通过覆盖开口 提供覆盖扩散器物体20的第一气缸30,并且设置覆盖第一气缸30的第二气缸40。 从节水盘10的通孔11喷射的水被扩散器物体20扩散,扩散水被第一缸30的内壁容纳。进气孔33形成在上部 并且当通过流入扩散器物体20和第一缸30之间的水通道71的水流而使第一缸30的空气压力减小时,外部空气通过形成的通风通道72通风 通过进气孔33在第一汽缸30和第二汽缸40之间,通过混合水流和空气来产生气泡形式的水。
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公开(公告)号:USD947325S1
公开(公告)日:2022-03-29
申请号:US29764895
申请日:2021-01-04
申请人: Masaaki Takano
设计人: Masaaki Takano
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公开(公告)号:US09297153B2
公开(公告)日:2016-03-29
申请号:US13260034
申请日:2009-03-26
申请人: Masaaki Takano
发明人: Masaaki Takano
CPC分类号: E03C1/084 , B05B7/0425 , Y02A20/411
摘要: The present invention provides a water saving aerator that can generate high quality babble foam water including the fine bubble entirely. The water saving aerator is attached to the water facilities such as the water tap for generating bubble foam water and flowing the bubble foam water. The water saving aerator comprises a water flow forming portion 110 for forming the water flow through the water saving aerator; a ventilation pass 120 for supplying the outer air to the water flow from the side direction via an air intake hole 121 installed on the side surface of a water flow cylinder; and a water flow accelerator 111 for accelerating the water flow supplied from the water flow forming portion and jetting an accelerated water flow jet. The accelerated water flow jet accelerated by the water flow accelerator 111 is jetted to the air supplied from the air intake hole 121, the bubble foam water flow is generated by mixing the air supplied from the air intake hole 121 into the water flow by the force generated by the accelerated water flow jet.
摘要翻译: 本发明提供一种能够完全产生包括微小气泡的高品质泡沫水的节水曝气器。 节水曝气器连接到水设备上,例如用于产生泡沫泡沫水的水龙头和使泡沫泡沫水流动。 节水曝气器包括用于形成通过节水曝气器的水流的水流形成部分110; 通过经由安装在水流筒的侧面上的吸气孔121从外侧向外侧空气供给外部空气的通气路径120; 以及水流加速器111,用于加速从水流形成部供给的水流并喷射加速的水流喷射。 由水流加速器111加速的加速水流喷射被喷射到从进气孔121供给的空气中,通过将从空气吸入孔121供给的空气与供给到水流中的空气混合而产生泡沫水泡流 由加速水流射流产生。
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公开(公告)号:US09033260B2
公开(公告)日:2015-05-19
申请号:US13127154
申请日:2008-10-31
申请人: Masaaki Takano
发明人: Masaaki Takano
CPC分类号: E03C1/084 , B05B7/0425 , B05B15/65 , Y02A20/411
摘要: The present invention provides a water saving aerator that can reduce the amount of water flow and generate bubble foam water from water provided by the water delivery apparatus such as a water tap. The water saving aerator comprises a water saving disc 10 for controlling the amount of water from the water tap 200, having the through-hole 11 whose diameter is smaller than that of the water tap 200, so the water flow is injected by covering the opening of the water tap 200. A first cylinder 30 covering a diffuser object 20 is provided and a second cylinder 40 covering the first cylinder 30 is provided. The water injected from the through-hole 11 of the water saving disc 10 is diffused by the diffuser object 20, and the diffused water is received by the inner wall of the first cylinder 30. An air intake hole 33 is formed on the upper portion of the first cylinder 30, and when the air pressure of the first cylinder 30 is decreased by the water flow running into the water pass 71 between the diffuser object 20 and the first cylinder 30, the outer air is ventilated through the ventilation pass 72 formed between the first cylinder 30 and the second cylinder 40 via the air intake hole 33, the bubble form water is generated by mixing the water flow and air.
摘要翻译: 本发明提供一种节水曝气器,其可以减少水流量,并且由诸如水龙头的输水装置提供的水产生泡沫泡沫水。 节水充气机包括一个用于控制来自水龙头200的水量的节水盘10,其具有直径小于水龙头200直径的通孔11,因此水流通过覆盖开口 提供覆盖扩散器物体20的第一气缸30,并且设置覆盖第一气缸30的第二气缸40。 从节水盘10的通孔11喷射的水被扩散器物体20扩散,扩散水被第一缸30的内壁容纳。进气孔33形成在上部 并且当通过流入扩散器物体20和第一缸30之间的水通道71的水流而使第一缸30的空气压力减小时,外部空气通过形成的通风通道72通风 通过进气孔33在第一汽缸30和第二汽缸40之间,通过混合水流和空气来产生气泡形式的水。
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公开(公告)号:US20120024984A1
公开(公告)日:2012-02-02
申请号:US13260034
申请日:2009-03-26
申请人: Masaaki Takano
发明人: Masaaki Takano
IPC分类号: E03C1/086
CPC分类号: E03C1/084 , B05B7/0425 , Y02A20/411
摘要: The present invention provides a water saving aerator that can generate high quality babble foam water including the fine bubble entirely. The water saving aerator is attached to the water facilities such as the water tap for generating bubble foam water and flowing the bubble foam water. The water saving aerator comprises a water flow forming portion 110 for forming the water flow through the water saving aerator; a ventilation pass 120 for supplying the outer air to the water flow from the side direction via an air intake hole 121 installed on the side surface of a water flow cylinder; and a water flow accelerator 111 for accelerating the water flow supplied from the water flow forming portion and jetting an accelerated water flow jet. The accelerated water flow jet accelerated by the water flow accelerator 111 is jetted to the air supplied from the air intake hole 121, the bubble foam water flow is generated by mixing the air supplied from the air intake hole 121 into the water flow by the force generated by the accelerated water flow jet.
摘要翻译: 本发明提供一种能够完全产生包括微小气泡的高品质泡沫水的节水曝气器。 节水曝气器连接到水设备上,例如用于产生泡沫泡沫水的水龙头和使泡沫泡沫水流动。 节水曝气器包括用于形成通过节水曝气器的水流的水流形成部分110; 通过经由安装在水流筒的侧面上的吸气孔121从外侧向外侧空气供给外部空气的通气路径120; 以及水流加速器111,用于加速从水流形成部供给的水流并喷射加速的水流喷射。 由水流加速器111加速的加速水流喷射被喷射到从进气孔121供给的空气中,通过将从空气吸入孔121供给的空气与供给到水流中的空气混合而产生泡沫水泡流 由加速水流射流产生。
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公开(公告)号:US07777038B2
公开(公告)日:2010-08-17
申请号:US10582014
申请日:2005-09-26
申请人: Takeshi Kuroda , Takahito Yamauchi , Tomoichi Shinohara , Kunio Oshima , Chiharu Kitajima , Hitoshi Nagao , Tae Fukushima , Takahiro Tomoyasu , Hironobu Ishiyama , Kazuhide Ohta , Masaaki Takano , Takumi Sumida
发明人: Takeshi Kuroda , Takahito Yamauchi , Tomoichi Shinohara , Kunio Oshima , Chiharu Kitajima , Hitoshi Nagao , Tae Fukushima , Takahiro Tomoyasu , Hironobu Ishiyama , Kazuhide Ohta , Masaaki Takano , Takumi Sumida
IPC分类号: C07D215/38
CPC分类号: C07D471/08 , C07D417/04 , C07D417/06 , C07D417/14 , C07D487/04 , C07D495/04
摘要: The present invention provides a carbostyril compound represented by General Formula (1) or a salt thereof, wherein A is a direct bond, a lower alkylene group, or a lower alkylidene group; X is an oxygen atom or a sulfur atom; R4 and R5 each represent a hydrogen atom; the bond between the 3 and 4 positions of the carbostyril skeleton is a single bond or a double bond; R1 is a hydrogen atom, etc; R2 is a hydrogen atom, etc; and R3 is a hydrogen atom, etc. The carbostyril compound or salt thereof of the present invention induces the production of TFF, and thus is usable for the treatment and/or prevention of disorders such as alimentary tract diseases, oral diseases, upper respiratory tract diseases, respiratory tract diseases, eye diseases, cancers, and wounds.
摘要翻译: 本发明提供由通式(1)表示的喹诺酮化合物或其盐,其中A为直接键,低级亚烷基或低级亚烷基; X是氧原子或硫原子; R4和R5各自表示氢原子; 喹诺酮骨架的3和4位之间的键是单键或双键; R1是氢原子等; R2是氢原子等; R3是氢原子等。本发明的喹诺酮化合物或其盐诱导TFF的产生,因此可用于治疗和/或预防诸如消化道疾病,口腔疾病,上呼吸道疾病 疾病,呼吸道疾病,眼睛疾病,癌症和伤口。
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