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公开(公告)号：US08641701B2
公开(公告)日：2014-02-04
申请号：US12449988
申请日：2008-03-06
申请人： Masanori Hangai , Nagahisa Yoshimura , Masaaki Nakahara , Kazunori Miyata , Tetsuya Eguchi , Yasuhiro Osakabe
发明人： Masanori Hangai , Nagahisa Yoshimura , Masaaki Nakahara , Kazunori Miyata , Tetsuya Eguchi , Yasuhiro Osakabe
IPC分类号： A61B18/18
CPC分类号： A61F9/00763 , A61F9/008 , A61F9/00821 , A61F2009/00874 , A61F2009/00887 , A61M1/008 , A61M2210/0612
摘要： There is provided a probe type living body tissue removing device comprising a probe unit having a probe formed in a capillary tube shape and an opening hole portion for internally aspirating a living body tissue, and also having a dissection device arranged within the probe and dissecting the living body tissue aspirated into the probe from the opening hole portion of the probe; wherein an aspiration force supplying device for supplying aspiration force to the probe unit, and a dissection driving source supplying device for supplying power or energy for fulfilling a function of the dissection device to the probe unit are connected to the probe unit; and the probe type living body tissue removing device dissects, and aspirates and removes the living body tissue by the dissecting means while the probe is inserted into the living body tissue and the living body tissue is aspirated through the opening hole portion; and a plurality of the opening hole portions of the probe are arranged.
摘要翻译： 提供了一种探针型生物体去除装置，其包括具有毛细管形状的探针的探针单元和用于内部抽吸生物体组织的开孔部，并且还具有布置在探针内的解剖装置， 活体组织从探针的开孔部吸入探针; 其特征在于，所述探针单元连接有用于向所述探针单元供给吸引力的吸引力供给装置，以及用于向所述探针单元供应用于将所述解剖装置的功能供应的能量或能量的解剖驱动源供给装置。 并且探针型生物体组织去除装置解剖，并且在探针插入到生物体组织中并且通过开孔部抽吸活体组织时，通过解剖装置吸出和去除生物体组织; 并且布置有多个探针的开孔部。
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公开(公告)号：US20100106054A1
公开(公告)日：2010-04-29
申请号：US12449988
申请日：2008-03-06
申请人： Masanori Hangai , Nagahisa Yoshimura , Masaaki Nakahara , Kazunori Miyata , Tetsuya Eguchi , Yasuhiro Osakabe
发明人： Masanori Hangai , Nagahisa Yoshimura , Masaaki Nakahara , Kazunori Miyata , Tetsuya Eguchi , Yasuhiro Osakabe
IPC分类号： A61B10/02
CPC分类号： A61F9/00763 , A61F9/008 , A61F9/00821 , A61F2009/00874 , A61F2009/00887 , A61M1/008 , A61M2210/0612
摘要： There is provided a probe type living body tissue removing device comprising a probe unit having a probe formed in a capillary tube shape and an opening hole portion for internally aspirating a living body tissue, and also having a dissection device arranged within the probe and dissecting the living body tissue aspirated into the probe from the opening hole portion of the probe; wherein an aspiration force supplying device for supplying aspiration force to the probe unit, and a dissection driving source supplying device for supplying power or energy for fulfilling a function of the dissection device to the probe unit are connected to the probe unit; and the probe type living body tissue removing device dissects, and aspirates and removes the living body tissue by the dissecting means while the probe is inserted into the living body tissue and the living body tissue is aspirated through the opening hole portion; and a plurality of the opening hole portions of the probe are arranged.
摘要翻译： 提供了一种探针型生物体去除装置，其包括具有毛细管形状的探针的探针单元和用于内部抽吸生物体组织的开孔部，并且还具有布置在探针内的解剖装置， 活体组织从探针的开孔部吸入探针; 其特征在于，所述探针单元连接有用于向所述探针单元供给吸引力的吸引力供给装置，以及用于向所述探针单元供应用于将所述解剖装置的功能供应的能量或能量的解剖驱动源供给装置。 并且探针型生物体组织去除装置解剖，并且在探针插入到生物体组织中并且通过开孔部抽吸活体组织时，通过解剖装置吸出和去除生物体组织; 并且布置有多个探针的开孔部。
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3.发明授权公开(公告)号：US07641339B2
公开(公告)日：2010-01-05
申请号：US11882236
申请日：2007-07-31
摘要： An ophthalmologic examination apparatus 1 projects a light onto a fundus oculi, detects the reflected light thereof, and forms a 3-dimensional image that represents the morphology of a retina based on the detected results. A stimulation-position specifying part 233 specifies, in the 3-dimensional image, a plurality of stimulation positions that correspond to a plurality of stimulation points Pi in a visual-field examination. A layer-thickness measuring part 235 analyzes the 3-dimensional image to find the layer thickness of the retina at each stimulation position. In addition, a displacement calculation part 234 specifies a related position of the stimulation position. A layer-thickness measuring part 235 finds the layer thickness of the retina at the related position.
摘要翻译： 眼科检查装置1将眼睛投射到眼底，检测其反射光，并且基于检测结果形成表示视网膜的形态的3维图像。 刺激位置确定部233在三维图像中指定与视野检查中的多个刺激点Pi对应的多个刺激位置。 层厚测量部分235分析三维图像以在每个刺激位置找到视网膜的层厚度。 此外，位移计算部234指定刺激位置的相关位置。 层厚测量部件235找到相关位置处的视网膜的层厚度。
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4.发明申请公开(公告)号：US20090033870A1
公开(公告)日：2009-02-05
申请号：US11882236
申请日：2007-07-31
摘要： An ophthalmologic examination apparatus 1 projects a light onto a fundus oculi, detects the reflected light thereof, and forms a 3-dimensional image that represents the morphology of a retina based on the detected results. A stimulation-position specifying part 233 specifies, in the 3-dimensional image, a plurality of stimulation positions that correspond to a plurality of stimulation points Pi in a visual-field examination. A layer-thickness measuring part 235 analyzes the 3-dimensional image to find the layer thickness of the retina at each stimulation position. In addition, a displacement calculation part 234 specifies a related position of the stimulation position. A layer-thickness measuring part 235 finds the layer thickness of the retina at the related position.
摘要翻译： 眼科检查装置1将眼睛投射到眼底，检测其反射光，并且基于检测结果形成表示视网膜的形态的3维图像。 刺激位置确定部233在三维图像中指定与视野检查中的多个刺激点Pi对应的多个刺激位置。 层厚测量部分235分析三维图像以在每个刺激位置找到视网膜的层厚度。 此外，位移计算部234指定刺激位置的相关位置。 层厚测量部件235找到相关位置处的视网膜的层厚度。
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公开(公告)号：US20080147039A1
公开(公告)日：2008-06-19
申请号：US11960978
申请日：2007-12-20
CPC分类号： A61K49/0076 , A61K31/717 , A61K31/728 , A61K31/765 , A61K49/0054 , A61K49/006
摘要： A vitreous body visualization agent which is to be injected into the eye to visualize the vitreous body by a safe and sure method. The vitreous body visualization agent is prepared by using a polymeric substance having positively or negatively charged functional groups and adding a hardly water-soluble and non-steroidal colored substance, in which the polymeric substance is to be suspended, thereto. Due to having a non-steroidal nature, it can be safely injected into the eye, and the colored substance, in which the polymeric substance is to be suspended, makes the vitreous body visually recognizable.
摘要翻译： 一种玻璃体可视化剂，其被注射到眼睛中以通过安全可靠的方法观察玻璃体。 通过使用具有正或负电荷的官能团的聚合物质，并将其中悬浮聚合物质的几乎难溶的和非甾体色的物质加入，制备玻璃体可视化试剂。 由于具有非甾体性质，可以将其安全地注射到眼睛中，并且其中悬浮聚合物质的有色物质使得玻璃体目视识别。
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公开(公告)号：US09206129B2
公开(公告)日：2015-12-08
申请号：US13876596
申请日：2011-09-30
申请人： Akira Kakizuka , Seiji Hori , Hanako Ikeda , Nagahisa Yoshimura , Noriko Nakano , Toshiyuki Shudo , Tomohiro Fuchigami
发明人： Akira Kakizuka , Seiji Hori , Hanako Ikeda , Nagahisa Yoshimura , Noriko Nakano , Toshiyuki Shudo , Tomohiro Fuchigami
IPC分类号： C07D213/76 , A61K31/4418 , C07D213/77
CPC分类号： C07D213/76 , A61K31/4418 , C07D213/77
摘要： The present invention provides agents effective to treat eye diseases, pharmaceutical compositions comprising them, methods for preparing pharmaceuticals for treatment of eye diseases comprising using the agents, use of the agents in manufacture of pharmaceuticals for treatment of eye diseases and methods for treating eye diseases comprising administering the agents or the pharmaceutical compositions. The eye diseases treated by the present invention include particularly glaucoma, especially normal tension glaucoma, or retinitis pigmentosa. The present invention provides the compound of formula (I) wherein R is as defined in the description.
摘要翻译： 本发明提供了有效治疗眼睛疾病的药剂，包含它们的药物组合物，用于治疗眼部疾病的药物的制备方法，包括使用该药剂，制备用于治疗眼部疾病的药物的用途以及治疗眼部疾病的方法的用途，所述方法包括 给药或药物组合物。 通过本发明治疗的眼部疾病特别包括青光眼，特别是正常的紧张性青光眼或色素性视网膜炎。 本发明提供其中R如说明书中所定义的式（I）化合物。
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公开(公告)号：US20140148416A1
公开(公告)日：2014-05-29
申请号：US13876596
申请日：2011-09-30
申请人： Akira Kakizuka , Seiji Hori , Hanako Ikeda , Nagahisa Yoshimura , Noriko Nakano , Toshiyuki Shudo , Tomohiro Fuchigami
发明人： Akira Kakizuka , Seiji Hori , Hanako Ikeda , Nagahisa Yoshimura , Noriko Nakano , Toshiyuki Shudo , Tomohiro Fuchigami
IPC分类号： C07D213/76
CPC分类号： C07D213/76 , A61K31/4418 , C07D213/77
摘要： The present invention provides agents effective to treat eye diseases, pharmaceutical compositions comprising them, methods for preparing pharmaceuticals for treatment of eye diseases comprising using the agents, use of the agents in manufacture of pharmaceuticals for treatment of eye diseases and methods for treating eye diseases comprising administering the agents or the pharmaceutical compositions. The eye diseases treated by the present invention include particularly glaucoma, especially normal tension glaucoma, or retinitis pigmentosa. The present invention provides the compound of formula (I) wherein R is as defined in the description.
摘要翻译： 本发明提供了有效治疗眼睛疾病的药剂，包含它们的药物组合物，用于治疗眼部疾病的药物的制备方法，包括使用该药剂，制备用于治疗眼部疾病的药物的用途以及治疗眼部疾病的方法的用途，所述方法包括 给药或药物组合物。 通过本发明治疗的眼部疾病特别包括青光眼，特别是正常的紧张性青光眼或色素性视网膜炎。 本发明提供其中R如说明书中所定义的式（I）化合物。
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