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1.发明申请Cell Growth Inhibiting Film, Medical Instrument and Digestive System Stent 审中-公开细胞生长抑制膜，医疗器械和消化系统支架公开(公告)号：US20070275156A1
公开(公告)日：2007-11-29
申请号：US10580648
申请日：2004-11-26
CPC分类号： A61L31/146
摘要： A cell growth inhibiting film including a resin and having a porous structure formed at least on its surface, a cell growth inhibiting method including causing the surface of a film including a resin and having a porous structure formed at least on its surface to contact cells to inhibit growth of the cells in the contact area, a medical instrument including a medical instrument substrate and a film including a resin and having a porous structure formed at least on its surface, in which the surface of the medical instrument substrate is entirely or partially covered with the film, and a digestive system stent including a stent substrate and a film including a resin and having a porous structure formed by through-holes with an average pore size of 0.1 to 20 μm and a coefficient of variation in pore size of 30% or less, in which the stent substrate is covered with the film. According to the present invention, a material exhibiting cell growth inhibitory effects without using a physiologically active substance and suitable for forming a medical instrument, and a digestive system stent which secures a digestive system tubular cavity in the body and allows a digestive fluid and digestive enzymes contained therein to pass through, but blocks cancer cells, can be provided.
摘要翻译： 至少在其表面形成有具有多孔结构的树脂的细胞生长抑制膜，细胞生长抑制方法，包括使包含树脂的膜的表面至少在其表面形成的多孔结构的表面与细胞接触 抑制接触区域中的细胞生长，包括医疗仪器基板的医疗器械和包括树脂的膜，并且至少在其表面上形成有多孔结构，其中医疗器械基板的表面完全或部分覆盖 以及包括支架基板和包含树脂的薄膜的消化系统支架，并且具有通过平均孔径为0.1〜20μm的通孔形成的多孔结构，孔径的变异系数为30％ 或更少，其中支架基底被膜覆盖。 根据本发明，不使用生理活性物质并且适于形成医疗器械的细胞生长抑制作用的材料，以及消化系统支架，其将消化系统管状空腔固定在体内并允许消化液和消化酶 可以提供包含在其中的通道，但可以阻止癌细胞。
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公开(公告)号：US5993436A
公开(公告)日：1999-11-30
申请号：US184648
申请日：1998-11-03
摘要： An indwelling catheter is made of a polyurethane resin having a Shore hardness of 60D or more. The soft segment of the polyurethane resin is constituted by polycaprolactone. The indwelling catheter has a kinking resistance of 10 mm or more when measured at 37.degree. C. in wet state. The Young's modulus is at first 20 kgf/mm.sup.2 or more when measure at 25.degree. C. in dry state, and reduces to 15 kgf/mm.sup.2 or less by soaking it in water of 37.degree. C. for 5 minutes or less.
摘要翻译： 留置导管由肖氏硬度为60D以上的聚氨酯树脂制成。 聚氨酯树脂的软链段由聚己内酯构成。 当在湿态下在37℃下测量时，留置导管具有10mm以上的扭结阻力。 当干燥状态下在25℃下测定时，杨氏模量为20kgf / mm 2以上，通过在37℃的水中浸泡5分钟以下将其降低至15kgf / mm 2以下。
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公开(公告)号：US20100234852A1
公开(公告)日：2010-09-16
申请号：US12225437
申请日：2007-03-12
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2002/9517
摘要： The present invention provides a stent delivery catheter comprising: an inner tube which has a distal end and a proximal end and in which a stent is set around the outer circumferential surface at the distal end side of the inner tube; an outer tube having a distal end and a proximal end, being coaxially arranged around the outer circumference of the inner tube, and being relatively movable in the axial direction to the inner tube; and a drive means being arranged at the proximal end side of the inner tube and the outer tube and being capable of making the outer tube relatively movable towards the proximal end to the inner tube, wherein with the operation of the drive means, a liquid fluidly travels through the gap between the inner tube and the outer tube from the proximal end side to the distal end direction.
摘要翻译： 本发明提供了一种支架输送导管，包括：内管，其具有远端和近端，支架围绕内管的远端侧的外周面设置在该内管中; 具有远端和近端的外管，其与所述内管的外周同轴配置，并且能够沿轴向相对于所述内管移动; 以及驱动装置，其布置在所述内管和所述外管的近端侧，并且能够使所述外管能够朝向所述内管的所述近端相对移动，其中，通过所述驱动装置的操作， 从近端侧到远端方向穿过内管和外管之间的间隙。
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公开(公告)号：US20080046067A1
公开(公告)日：2008-02-21
申请号：US11630448
申请日：2005-06-24
申请人： Yoshihide Toyokawa
发明人： Yoshihide Toyokawa
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91541 , A61F2002/91558
摘要： A stent 2 comprising a ring-shaped stent unit 4 formed by a zigzag-shaped threadlike material 10 continuing in the circumferential direction and expandable in the radius direction R from a contracted state. At least one of turned edge portions 8a and 8b of the zigzag-shaped threadlike material 10 composing said stent unit 4 and at least one of turned edge portions 8a and 8b of the zigzag-shaped threadlike material 10 in another stent unit 4 being adjacent to the stent unit 4 in the axial direction are connected in the axial direction X by a connection portion 6. The turned edge portions 8a and 8b position by being shifted in the axial direction X of the stent from each other between said turned edge portions 8a and 8b next to each other in the circumferential direction Y.
摘要翻译： 一种支架2，其包括环状支架单元4，该环形支架单元4由沿圆周方向延伸并且从收缩状态沿径向R延伸的锯齿形线状材料10形成。 构成所述支架单元4的曲折形螺纹状材料10的弯曲边缘部分8a和8b中的至少一个以及另一个支架单元中的之字形螺纹状材料10的至少一个折边部分8a和8b中的至少一个 在轴向方向上邻近支架单元4的连接部分4通过连接部分6在轴向方向X上连接。通过在支架的轴向方向X之间相对移动，转动边缘部分8a和8b位于彼此之间 在圆周方向Y上彼此相邻的所述折边部分8a和8b。
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公开(公告)号：US07824439B2
公开(公告)日：2010-11-02
申请号：US11630448
申请日：2005-06-24
申请人： Yoshihide Toyokawa
发明人： Yoshihide Toyokawa
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91541 , A61F2002/91558
摘要： A stent of interconnected ring-shaped stent units formed by a continuous threadlike material that extends back and forth to form a zigzag pattern of segments extending between opposite side turned edge portions. The zigzag pattern forming the outer circumference of each ring-shaped stent unit with at least some of said turned edge portions at a same side of the segments having a shifted position along the stent axial direction relative to a position of others of said turned edge portions at that same side of the segments so that not all of the adjacent tuned edge portions at that same side of the segments are aligned along a common circle extending around the outer circumference of each ring-shaped stent unit. At least some of the turned edge portions are also formed to have a wider line width than the line width of the segments.
摘要翻译： 一种由连续的线状材料形成的互连的环形支架单元的支架，其前后延伸以形成在相对侧边缘部分之间延伸的段的锯齿形图案。 形成每个环形支架单元的外周的锯齿形图案，其中在所述段的同一侧的至少一些所述转向边缘部分沿着支架轴向方向相对于所述转向边缘部分中的其他位置的位置具有偏移位置 在段的同一侧，使得并非所有段的相同侧的相邻的调整边缘部分沿着围绕每个环形支架单元的外周延伸的公共圆对准。 至少一些转动边缘部分也形成为具有比线段的线宽更宽的线宽。
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公开(公告)号：US06482180B2
公开(公告)日：2002-11-19
申请号：US09776923
申请日：2001-02-06
申请人： Yoshihide Toyokawa , Kenji Ishikawa , Toshiya Asai
发明人： Yoshihide Toyokawa , Kenji Ishikawa , Toshiya Asai
IPC分类号： A61M500
CPC分类号： A61M25/0637 , A61M39/284
摘要： The present invention provides an intravascular catheter comprising a catheter part; an internal needle disposed through the catheter part; and a flexible resin member disposed on the outer surface of the catheter part. It is preferable that the intravascular catheter comprises a blood leakage prevention member for preventing leakage of blood by closing the catheter part via the flexible resin member. It is also preferable that the blood leakage prevention member comprises a pressure part capable of pressuring the catheter part via the flexible resin member. It is further preferable that the blood leakage prevention member comprises a fixing mechanism capable of fixing the pressure part in the pressuring state, and a releasing mechanism capable of releasing the pressuring state.
摘要翻译： 本发明提供一种血管内导管，其包括导管部分; 穿过导管部分设置的内针; 以及设置在导管部的外表面上的柔性树脂构件。 优选地，血管内导管包括通过经由柔性树脂构件封闭导管部来防止血液渗漏的防血漏部件。 还优选的是，防漏血部件包括能够经由柔性树脂部件对导管部进行加压的压力部。 进一步优选的是，防漏血部件包括能够将加压部固定在加压状态的固定机构和能够释放加压状态的释放机构。
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