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公开(公告)号：US07129064B2
公开(公告)日：2006-10-31
申请号：US10311776
申请日：2001-06-22
IPC分类号： C12P21/06
CPC分类号： C07K14/52 , A61K38/00 , C07K14/4753
摘要： A canine hepatocyte growth factor gene and a 15 base pairs-deleted gene thereof encode a protein having an amino acid sequence shown in SEQ ID NO: 2 or 4 and a protein having an amino acid sequence comprising a deletion, substitution or addition of one or several amino acids and having a canine hepatocyte growth factor activity. The canine hepatocyte growth factor and the 5 amino acids-deleted canine hepatocyte growth factor are useful for the treatment of liver diseases, kidney diseases, lung diseases, digestive diseases, cardiocirculatory diseases or cranial nerve diseases.
摘要翻译： 犬肝细胞生长因子基因和其15个碱基对缺失的基因编码具有SEQ ID NO：2或4所示氨基酸序列的蛋白质和具有包含缺失，取代或添加一个或多个氨基酸的氨基酸序列的蛋白质 几种氨基酸，具有犬肝细胞生长因子活性。 犬肝细胞生长因子和5个氨基酸缺失的犬肝细胞生长因子可用于治疗肝脏疾病，肾脏疾病，肺部疾病，消化系统疾病，心脏血管疾病或颅神经疾病。
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公开(公告)号：US20060217314A1
公开(公告)日：2006-09-28
申请号：US11450056
申请日：2006-06-09
IPC分类号： A61K38/18 , C07K14/475
CPC分类号： C07K14/4753 , A61K38/00
摘要： A feline hepatocyte growth factor gene and a 15 base pairs-deleted feline hepatocyte growth factor gene. These genes encode a protein having an amino acid sequence shown in SEQ ID NO: 2 or 4. The feline hepatocyte growth factor and the 5 amino acids-deleted feline hepatocyte growth factor are useful for the treatment of liver diseases, kidney diseases, lung diseases, digestive diseases, cardiocirculatory diseases or cranial nerve diseases.
摘要翻译： 一种肝细胞肝细胞生长因子基因和15个碱基对缺失的肝细胞生长因子基因。 这些基因编码具有SEQ ID NO：2或4所示的氨基酸序列的蛋白质。猫肝细胞生长因子和5个氨基酸缺失的猫肝细胞生长因子可用于治疗肝脏疾病，肾脏疾病，肺部疾病 ，消化系统疾病，心脏疾病或脑神经疾病。
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公开(公告)号：US07125688B2
公开(公告)日：2006-10-24
申请号：US10297158
申请日：2001-05-30
IPC分类号： C12P25/06
CPC分类号： C07K14/4753 , A61K38/00
摘要： A feline hepatocyte growth factor gene and a 15 base pairs-deleted feline hepatocyte growth factor gene. These genes encode a protein having an amino acid sequence shown in SEQ ID NO: 2 or 4. The feline hepatocyte growth factor and the 5 amino acids-deleted feline hepatocyte growth factor are useful for the treatment of liver diseases, kidney diseases, lung diseases, digestive diseases, cardiocirculatory diseases or cranial nerve diseases.
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公开(公告)号：US07425536B2
公开(公告)日：2008-09-16
申请号：US11450056
申请日：2006-06-09
IPC分类号： A61K38/00
CPC分类号： C07K14/4753 , A61K38/00
摘要： A feline hepatocyte growth factor gene and a 15 base pairs-deleted feline hepatocyte growth factor gene. These genes encode a protein having an amino acid sequence shown in SEQ ID NO: 2 or 4.The feline hepatocyte growth factor and the 5 amino acids-deleted feline hepatocyte growth factor are useful for the treatment of liver diseases, kidney diseases, lung diseases, digestive diseases, cardiocirculatory diseases or cranial nerve diseases.
摘要翻译： 一种肝细胞肝细胞生长因子基因和15个碱基对缺失的肝细胞生长因子基因。 这些基因编码具有SEQ ID NO：2或4所示的氨基酸序列的蛋白质。猫肝细胞生长因子和5个氨基酸缺失的猫肝细胞生长因子可用于治疗肝脏疾病，肾脏疾病，肺部疾病 ，消化系统疾病，心脏疾病或脑神经疾病。
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公开(公告)号：US20100190262A1
公开(公告)日：2010-07-29
申请号：US12452687
申请日：2007-07-20
申请人： Tetsuro Yamashita , Yasuyuki Suzuta
发明人： Tetsuro Yamashita , Yasuyuki Suzuta
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , G01N2333/4724 , G01N2333/918 , G01N2800/347
摘要： A method for diagnosing a kidney disease in a cat by detecting a cat urinary protein without being affected by cauxin, and a diagnostic agent therefor are provided. A method of detecting a urinary protein derived from renal dysfunction in a cat according to claim 1, wherein cauxin is removed from cat urine by bringing the cat urine into contact with a lectin or an anti-cauxin antibody that specifically binds to cauxin.
摘要翻译： 提供了一种通过检测猫尿蛋白而不受cauxin的影响来诊断猫的肾脏疾病的方法及其诊断剂。 2.根据权利要求1所述的猫的肾功能障碍的尿蛋白质检测方法，其特征在于，通过使猫尿与特异性结合cauxin的凝集素或抗Cauxin抗体接触，从猫尿中除去cauxin。
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公开(公告)号：US20090181121A1
公开(公告)日：2009-07-16
申请号：US11596361
申请日：2005-05-23
IPC分类号： A23K1/02
CPC分类号： A23K50/40 , A23K10/33 , A23K20/105 , A23K50/10 , Y02P60/871
摘要： γ-Aminobutyric acid is supplied to animal efficiently and inexpensively to effectively enhance stress-relieving effect on the animal.Livestock are allowed to lick γ-Aminobutyric acid mixed with molasses and solidified into feedstuff blocks, so that γ-aminobutyric acid is supplied to livestock together with molasses.
摘要翻译： 为动物提供高效，廉价的γ-氨基丁酸，有效增强对动物的缓解作用。 允许家畜舔与糖蜜混合并凝固成饲料块的γ-氨基丁酸，使得γ-氨基丁酸与糖蜜一起供应给家畜。
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公开(公告)号：US20120309110A1
公开(公告)日：2012-12-06
申请号：US13587255
申请日：2012-08-16
申请人： Tetsuro YAMASHITA , Yasuyuki Suzuta
发明人： Tetsuro YAMASHITA , Yasuyuki Suzuta
IPC分类号： G01N33/566 , G01N33/68
CPC分类号： G01N33/6893 , G01N2333/4724 , G01N2333/918 , G01N2800/347
摘要： A method for diagnosing a kidney disease in a cat by detecting a cat urinary protein without being affected by cauxin, and a diagnostic agent therefor are provided. A method of detecting a urinary protein derived from renal dysfunction in a cat according to claim 1, wherein cauxin is removed from cat urine by bringing the cat urine into contact with a lectin or an anti-cauxin antibody that specifically binds to cauxin.
摘要翻译： 提供了一种通过检测猫尿蛋白而不受cauxin的影响来诊断猫的肾脏疾病的方法及其诊断剂。 2.根据权利要求1所述的猫的肾功能障碍的尿蛋白质检测方法，其特征在于，通过使猫尿与特异性结合cauxin的凝集素或抗Cauxin抗体接触，从猫尿中除去cauxin。
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8.发明授权Diagnostic kit for detecting urinary protein of a cat after cauxin removal 有权用于检测Cauxin去除后的猫的尿蛋白的诊断试剂盒公开(公告)号：US08268639B2
公开(公告)日：2012-09-18
申请号：US12452687
申请日：2007-07-20
申请人： Tetsuro Yamashita , Yasuyuki Suzuta
发明人： Tetsuro Yamashita , Yasuyuki Suzuta
IPC分类号： G01N33/545 , G01N33/548
CPC分类号： G01N33/6893 , G01N2333/4724 , G01N2333/918 , G01N2800/347
摘要： A method for diagnosing a kidney disease in a cat by detecting a cat urinary protein without being affected by cauxin, and a diagnostic agent therefor are provided. A method of detecting a urinary protein derived from renal dysfunction in a cat according to claim 1, wherein cauxin is removed from cat urine by bringing the cat urine into contact with a lectin or an anti-cauxin antibody that specifically binds to cauxin.
摘要翻译： 提供了一种通过检测猫尿蛋白而不受cauxin的影响来诊断猫的肾脏疾病的方法及其诊断剂。 2.根据权利要求1所述的猫的肾功能障碍的尿蛋白质检测方法，其特征在于，通过使猫尿与特异性结合cauxin的凝集素或抗Cauxin抗体接触，从猫尿中除去cauxin。
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公开(公告)号：US08962705B2
公开(公告)日：2015-02-24
申请号：US13579897
申请日：2011-02-17
申请人： Shinya Matsuno , Kyoichi Saito , Tetsuro Yamashita , Ayako Ito , Yasuyuki Suzuta
发明人： Shinya Matsuno , Kyoichi Saito , Tetsuro Yamashita , Ayako Ito , Yasuyuki Suzuta
IPC分类号： C08F255/02 , C08F257/02 , C08F259/00 , C08F263/04 , C08F283/04 , C08J9/36 , G01N33/68 , C12Q1/44
CPC分类号： G01N33/6893 , C12Q1/44 , G01N2333/918 , G01N2800/347
摘要： A method for removing cauxin in cat urine and a material for removing cauxin are provided. The material for removing cauxin in cat urine comprises a polymer substrate on which surface a trifluoroketone derivative is immobilized via dithiol.
摘要翻译： 提供了一种去除猫尿中的cauxin的方法和用于去除cauxin的材料。 用于除去猫尿中的cauxin的材料包括通过二硫醇固定有三氟酮衍生物的表面的聚合物基材。
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10.发明授权Method of diagnosing renal dysfunction in a cat based on non-cauxin protein levels 有权基于非cauxin蛋白水平诊断猫的肾功能障碍的方法公开(公告)号：US08415163B2
公开(公告)日：2013-04-09
申请号：US13587255
申请日：2012-08-16
申请人： Tetsuro Yamashita , Yasuyuki Suzuta
发明人： Tetsuro Yamashita , Yasuyuki Suzuta
IPC分类号： G01N33/545 , G01N33/548
CPC分类号： G01N33/6893 , G01N2333/4724 , G01N2333/918 , G01N2800/347
摘要： Disclosed is a method of diagnosing renal dysfunction in a cat by removing cauxin from cat urine and detecting a protein in the cat urine sample from which cauxin has been removed. Cauxin is removed from cat urine by bringing the cat urine into contact with a lectin or with an anti-cauxin antibody that specifically binds to cauxin. Cauxin may be removed using a column filled with a carrier that is bound to the lectin or to the anti-cauxin antibody. The lectin may be Lens culinaris lectin. Detection of the cat urinary protein from which cauxin has been removed is performed with a urine test strip.
摘要翻译： 本发明公开了一种通过从猫尿中除去cauxin并检测已经除去cauxin的猫尿样品中的蛋白质来诊断猫的肾功能障碍的方法。 通过使猫尿与凝集素或与cauxin特异性结合的抗Cauxin抗体接触，将Cauxin从猫尿中除去。 可以使用填充有与凝集素结合的载体的柱或抗Cauxin抗体来除去Cauxin。 凝集素可能是镜头culinaris凝集素。 使用尿液测试条来检测已经去除cauxin的猫尿蛋白质。
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