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公开(公告)号：US5478520A
公开(公告)日：1995-12-26
申请号：US321476
申请日：1994-10-11
申请人： Masayoshi Kasai , Hideo Kuroda , Yukio Tamura , Yoshio Shikase , Kouji Kubota
发明人： Masayoshi Kasai , Hideo Kuroda , Yukio Tamura , Yoshio Shikase , Kouji Kubota
CPC分类号： B29C45/17 , B29C45/20 , B29C45/561 , B29C45/72 , B29C45/77 , B29C45/78 , B29C2045/0098 , B29C2045/5615
摘要： A process and apparatus for effecting injection molding of plastic resin products on an injection molding apparatus including a metal mold composed of a slidable mold element and a fixed mold element defining together the mold cavity, an actuator for sliding the slidable mold element and an injection nozzle for adjusting the nozzle flow path section, which comprises a first molding step of injecting a molten resin into the mold cavity which has been preset by the slidable mold element so as to include a post-compression margin to be compressed afterwards in a second molding step, to effect the injection under a reduced molding pressure, while causing a temperature elevation and, thus, a viscosity reduction of the molten resin, until the mold cavity has been filled up, and a second molding step of compressing the resin so charged in the mold cavity by operating the slidable mold element to compress the charged resin to compensate the post-compression margin, so as to allow an effective pressing force to be imposed onto the charged resin within the mold cavity also after the gate has been sealed.
摘要翻译： 一种用于在塑料树脂产品上进行注射成型的方法和装置，该注射成型装置包括由可滑动的模具元件和限定模具腔的模具元件组成的金属模具，用于滑动可滑动模具元件的致动器和注射喷嘴 用于调节喷嘴流路部分，其包括将熔融树脂注入到由可滑动模具元件预设的模腔中的第一模制步骤，以便在第二模制步骤中包括后压缩边缘以被压缩 在降低的成型压力下进行注射，同时引起熔融树脂的温度升高，从而降低熔融树脂，直到模腔被填满，并且第二模制步骤将如此填充的树脂压缩 通过操作可滑动模具元件来压缩带电树脂以补偿后压缩边缘，从而允许有效的模腔 也可以在门被密封之后施加在模腔内的带电树脂上的压力。
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公开(公告)号：US5098275A
公开(公告)日：1992-03-24
申请号：US580286
申请日：1990-09-11
申请人： Masayoshi Kasai , Hideo Kuroda , Sensho Saito
发明人： Masayoshi Kasai , Hideo Kuroda , Sensho Saito
CPC分类号： B29C45/18 , B29C31/10 , B29C45/76 , B29C47/92 , B29C2947/92076 , B29C2947/92257 , B29C2947/92485 , B29C2947/926 , B29C2947/92657 , B29C2947/92828 , B29C2947/92866 , B29C47/0009 , B29C47/1027 , B29C47/1045 , B29K2105/16
摘要： The invention is embodied as a raw material resin feeding apparatus for a molding machine, such as an injection molding machine or an extruder. In this system, upon carrying out a variable resin-change operation by making use of material to be changed, raw material resin is intermittently fed to a feed section by intermittently opening and closing a resin passageway. The improvements reside in that the apparatus includes a raw resin material feed selection mechanism provided midway along a resin passageway for selectively either feeding a predetermined amount intermittently or continuously to a feed section. A resin-change resin feed start detector mechanism is provided for detecting completion of discharge of the amount of raw material corresponding to the predetermined amount, and a resin-change completion detector mechanism is provided. With this apparatus, raw material can be selectively fed to effect quick resin-change or for normal operation.
摘要翻译： 本发明实施为成型机的原料树脂供给装置，例如注塑机或挤出机。 在该系统中，通过利用改变材料进行可变的树脂变更操作，通过间歇地打开和关闭树脂通道将原料树脂间歇地供给到进料部分。 改进之处在于，该设备包括沿着树脂通道中途设置的原料树脂材料供料选择机构，用于选择性地间歇地或连续地向进料部分供给预定量。 设置树脂变化树脂进料启动检测器机构，用于检测对应于预定量的原料量的排出的完成，并且提供树脂改变完成检测器机构。 利用该装置，可以选择性地供给原料以实现快速树脂改变或正常操作。
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公开(公告)号：US5246949A
公开(公告)日：1993-09-21
申请号：US908890
申请日：1992-07-08
申请人： Mitsuhiro Yoshida , Hiroyuki Fujimori , Yoshio Ishino , Akira Sasaki , Masayoshi Kasai , Keiji Ohmori , Noriko Konita , Yoshifumi Yuasa , Toyohiko Kobayashi
发明人： Mitsuhiro Yoshida , Hiroyuki Fujimori , Yoshio Ishino , Akira Sasaki , Masayoshi Kasai , Keiji Ohmori , Noriko Konita , Yoshifumi Yuasa , Toyohiko Kobayashi
IPC分类号： A61K9/00 , A61K9/70 , A61K31/22 , A61K31/44 , A61K47/10 , A61K47/14 , C07C219/28 , C07D213/80
CPC分类号： C07D213/80 , A61K31/22 , A61K31/44 , A61K47/10 , A61K47/14 , A61K9/0014 , A61K9/7053 , A61K9/7076 , C07C219/28 , Y10S514/947
摘要： (A) a diacylated dopamine derivative represented by the formula (I): ##STR1## wherein R.sup.1 represents an alkyl group having 3 to 7 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms, substituted or unsubstituted phenyl group or a substituted or unsubstituted nitrogen-containing heterocyclic group; and R.sup.2 represents a hydrogen atom or a lower alkyl group; or a salt thereof; and(B) one or more compounds selected from lactic acid esters, fatty acid monoglycerides and higher alcohols; optionally together with(C) an unsaturated fatty acid monohydric alcohol ester. This preparation has a sustained effect, a high skin permeability and a low skin irritativeness.
摘要翻译： （A）由式（I）表示的二酰化多巴胺衍生物：其中R 1表示具有3至7个碳原子的烷基，具有3至6个碳原子的环烷基，取代或未取代的苯基或 取代或未取代的含氮杂环基; 并且R 2表示氢原子或低级烷基; 或其盐; 和（B）一种或多种选自乳酸酯，脂肪酸单甘油酯和高级醇的化合物; 任选地与（C）不饱和脂肪酸一元醇酯一起。 这种制剂具有持续的作用，高的皮肤渗透性和低的皮肤刺激性。
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公开(公告)号：US4994279A
公开(公告)日：1991-02-19
申请号：US302646
申请日：1989-01-26
CPC分类号： A61K9/5078
摘要： A multi-layered granule comprises an inner, slow-releasing layer, an outer, rapid-releasing layer and an intermediate layer provided between said slow-releasing layer and said rapid-releasing layer which intermediate layer comprises a hardened oil and hydroxypropyl cellulose or methyl cellulose.
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公开(公告)号：US5204119A
公开(公告)日：1993-04-20
申请号：US748208
申请日：1991-08-20
申请人： Takao Shiobara , Jun Nonaka , Masayoshi Kasai , Takeshi Konita
发明人： Takao Shiobara , Jun Nonaka , Masayoshi Kasai , Takeshi Konita
IPC分类号： A61K47/02 , A61K9/14 , A61K31/19 , A61K31/405
CPC分类号： A61K31/19 , A61K31/405 , A61K9/143 , Y10S514/947
摘要： An external preparation is characterized by comprising calcium silicate. The calcium silicate controls the release rate and percutaneous absorbability of a drug.
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公开(公告)号：US4853211A
公开(公告)日：1989-08-01
申请号：US117398
申请日：1987-10-28
申请人： Toshio Kurobe , Masayoshi Kasai , Masanori Kayano
发明人： Toshio Kurobe , Masayoshi Kasai , Masanori Kayano
CPC分类号： A61K9/0034 , Y10S514/967
摘要： An effervescent vaginal suppository composition containing a stabilizer appropriately selected from the group consisting of anhydrous sodium sulfate, anhydrous silica gel, dried magnesium silicate, dried aluminum silicate, dried calcium carboxymethylcellulose, dried microcrystalline cellulose, dried starch and dried calcium phosphate or mixtures thereof, preferably in an amount of 0.1-20% based on the weight of said effervescent vaginal suppository composition. Shaped effervescent vaginal suppositories are produced therefrom.
摘要翻译： 一种泡腾阴道栓剂组合物，其含有适当选自无水硫酸钠，无水硅胶，干燥硅酸镁，干燥硅酸铝，干燥的羧甲基纤维素钙，干燥的微晶纤维素，干淀粉和干燥的磷酸钙或其混合物的稳定剂， 其用量为所述泡腾阴道栓剂组合物重量的0.1-20％。 由此产生形状的泡腾阴道栓剂。
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7.发明授权Pharmaceutical preparation for percutaneous administration containing bunazosin or its salt 失效含有布那唑嗪或其盐的经皮给药的药物制剂
公开(公告)号：US5041437A
公开(公告)日：1991-08-20
申请号：US428240
申请日：1989-10-27
申请人： Mitsuhiro Yoshida , Hiroyuki Fujimori , Hidenori Asakawa , Masayoshi Kasai , Masanori Kayano , Shigemitsu Osawa
发明人： Mitsuhiro Yoshida , Hiroyuki Fujimori , Hidenori Asakawa , Masayoshi Kasai , Masanori Kayano , Shigemitsu Osawa
CPC分类号： A61K31/55 , A61K47/14 , A61K9/0014 , Y10S514/929
摘要： A pharmaceutical composition comprises (a) a pharmacologically effective amount of bunazosin or a pharmacologically acceptable salt thereof and (b) a monoglyceride of a fatty acid having 8 to 12 carbon atoms and/or a lactic acid ester of an aliphatic alcohol having 12 to 18 carbon atoms and is improved in percutaneous administration. ##STR1##
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公开(公告)号：US4037930A
公开(公告)日：1977-07-26
申请号：US674041
申请日：1976-04-05
IPC分类号： G02F1/1341 , G02F1/13
CPC分类号： G02F1/1341
摘要： In a liquid crystal display cell wherein two glass plates are sealed to a peripheral sealing member provided with a liquid crystal inlet port, the peripheries of the glass plates generally project slightly beyond the periphery of the peripheral sealing member thus forming a shallow groove. Low melting point glass filler is filled in the groove about the inlet port. A metal layer is applied onto the filler and finally a solder layer is applied onto the metal layer to seal the inlet port.
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