公开(公告)号：US20200066375A1

公开(公告)日：2020-02-27

申请号：US16441647

申请日：2019-06-14

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Manolis Kellis ,  Jicong Cao ,  Eva Maria Novoa Pardo ,  Zhizhuo Zhang

IPC: G16B20/50 ,  G16B40/00 ,  C12N15/10 ,  C12N15/11

Abstract: Disclosed herein are novel 5′ UTR sequences that can be used to control gene expression in various contexts. Also disclosed herein are methods of engineering 5′ UTR sequences and methods and kits for screening 5′ UTR sequences for a property of interest.

公开(公告)号：US11875876B2

公开(公告)日：2024-01-16

申请号：US16441647

申请日：2019-06-14

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Manolis Kellis ,  Jicong Cao ,  Eva Maria Novoa Pardo ,  Zhizhuo Zhang

IPC: C12N15/11 ,  G16B20/50 ,  G16B40/00 ,  C12N15/10 ,  C12N15/85

CPC classification number: G16B20/50 ,  C12N15/1089 ,  C12N15/11 ,  C12N15/85 ,  G16B40/00

Abstract: Disclosed herein are novel 5′ UTR sequences that can be used to control gene expression in various contexts. Also disclosed herein are methods of engineering 5′ UTR sequences and methods and kits for screening 5′ UTR sequences for a property of interest.