公开(公告)号：US20190125934A1

公开(公告)日：2019-05-02

申请号：US15794432

申请日：2017-10-26

Applicant: Massachusetts Institute of Technology

Inventor： Xuanhe Zhao ,  German Alberto Parada Hernandez ,  Hyunwoo Yuk

IPC: A61L29/14 ,  A61L29/08 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L29/16 ,  G01N21/80

Abstract: Hydrogel-substrate laminate structures and tough biocompatible hydrogel coatings for various equipment such as medical devices and underwater equipment, in which robust interfaces are formed between the hydrogel coatings and the substrate/equipment surface(s). The hydrogel coatings provide a highly-hydrated, ultra-low friction structure that does not rupture or delaminate under stress. The hydrogel coatings may further incorporate a variety of therapeutic agents and/or sensing mechanisms to provide for environmental sensing and therapeutic agent release.