公开(公告)号：US20190106683A1

公开(公告)日：2019-04-11

申请号：US16166523

申请日：2018-10-22

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Hiroki Ando ,  Sebastien Lemire

IPC: C12N7/00

Abstract: Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity.

公开(公告)号：US11186830B2

公开(公告)日：2021-11-30

申请号：US16166523

申请日：2018-10-22

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Hiroki Ando ,  Sebastien Lemire

IPC: C12N7/00 ,  C12N7/02 ,  C12N15/81

Abstract: Disclosed here are recombinant bacteriophages with tail fibers encoded by at least two subsets of genomic fragments from different bacteriophage having different host ranges.

公开(公告)号：US20150064770A1

公开(公告)日：2015-03-05

申请号：US14478657

申请日：2014-09-05

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Hiroki Ando ,  Sebastien Lemire

IPC: C12N7/00

CPC classification number: C12N7/00 ,  C12N7/02 ,  C12N15/81 ,  C12N2795/00011 ,  C12N2795/00021

Abstract: Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity.

Abstract translation: 本发明的各个方面和实施方案涉及高通量噬菌体工程方法和具有可控的宿主范围的用于控制噬菌体特异性的重组噬菌体。

公开(公告)号：US09617522B2

公开(公告)日：2017-04-11

申请号：US14478657

申请日：2014-09-05

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Hiroki Ando ,  Sebastien Lemire

IPC: C12N7/00 ,  C12N7/02 ,  C12N15/81

CPC classification number: C12N7/00 ,  C12N7/02 ,  C12N15/81 ,  C12N2795/00011 ,  C12N2795/00021

Abstract: Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity.

公开(公告)号：US20170183634A1

公开(公告)日：2017-06-29

申请号：US15445700

申请日：2017-02-28

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Hiroki Ando ,  Sebastien Lemire

IPC: C12N7/00

CPC classification number: C12N7/00 ,  C12N7/02 ,  C12N15/81 ,  C12N2795/00011 ,  C12N2795/00021

Abstract: Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity.