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公开(公告)号:US11186830B2
公开(公告)日:2021-11-30
申请号:US16166523
申请日:2018-10-22
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Kuan-Ta Lu , Hiroki Ando , Sebastien Lemire
Abstract: Disclosed here are recombinant bacteriophages with tail fibers encoded by at least two subsets of genomic fragments from different bacteriophage having different host ranges.
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公开(公告)号:US20150064770A1
公开(公告)日:2015-03-05
申请号:US14478657
申请日:2014-09-05
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Kuan-Ta Lu , Hiroki Ando , Sebastien Lemire
IPC: C12N7/00
CPC classification number: C12N7/00 , C12N7/02 , C12N15/81 , C12N2795/00011 , C12N2795/00021
Abstract: Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity.
Abstract translation: 本发明的各个方面和实施方案涉及高通量噬菌体工程方法和具有可控的宿主范围的用于控制噬菌体特异性的重组噬菌体。
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公开(公告)号:US20200277605A1
公开(公告)日:2020-09-03
申请号:US16815072
申请日:2020-03-11
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Kuan-Ta Lu , Sebastien Lemire , Andrew C. Yang , Kevin M. Yehl
IPC: C12N15/113 , G01N33/569 , A61P31/04 , C07K14/005
Abstract: Disclosed herein are novel synthetic bacteriophages and bacteriophage compositions, methods of production thereof, and therapeutic uses thereof.
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公开(公告)号:US20190106683A1
公开(公告)日:2019-04-11
申请号:US16166523
申请日:2018-10-22
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Kuan-Ta Lu , Hiroki Ando , Sebastien Lemire
IPC: C12N7/00
Abstract: Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity.
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公开(公告)号:US11091762B2
公开(公告)日:2021-08-17
申请号:US16815072
申请日:2020-03-11
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Kuan-Ta Lu , Sebastien Lemire , Andrew C. Yang , Kevin M. Yehl
IPC: C12N9/22 , C12Q1/68 , C12N15/113 , C12N15/74 , C12N15/70 , G01N33/569 , A61P31/04 , C07K14/005
Abstract: Disclosed herein are novel synthetic bacteriophages and bacteriophage compositions, methods of production thereof, and therapeutic uses thereof.
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公开(公告)号:US20170183634A1
公开(公告)日:2017-06-29
申请号:US15445700
申请日:2017-02-28
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Kuan-Ta Lu , Hiroki Ando , Sebastien Lemire
IPC: C12N7/00
CPC classification number: C12N7/00 , C12N7/02 , C12N15/81 , C12N2795/00011 , C12N2795/00021
Abstract: Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity.
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公开(公告)号:US20180155721A1
公开(公告)日:2018-06-07
申请号:US15795510
申请日:2017-10-27
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Kuan-Ta Lu , Sebastien Lemire , Andrew C. Yang , Kevin M. Yehl
IPC: C12N15/113 , C07K14/005 , A61P31/04
CPC classification number: C12N15/113 , A61P31/04 , C07K14/005 , C12N2320/32 , C12N2330/30 , C12N2795/00021 , C12N2795/00032 , C12N2795/14122 , C12N2795/14132 , G01N33/56916
Abstract: Disclosed herein are novel synthetic bacteriophages and bacteriophage compositions, methods of production thereof, and therapeutic uses thereof.
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公开(公告)号:US09617522B2
公开(公告)日:2017-04-11
申请号:US14478657
申请日:2014-09-05
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Kuan-Ta Lu , Hiroki Ando , Sebastien Lemire
CPC classification number: C12N7/00 , C12N7/02 , C12N15/81 , C12N2795/00011 , C12N2795/00021
Abstract: Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity.
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