公开(公告)号：US11214661B2

公开(公告)日：2022-01-04

申请号：US15261163

申请日：2016-09-09

申请人： Massachusetts Institute of Technology

发明人： Samuel G. Rodriques ,  Daniel Oran ,  Ruixuan Gao ,  Shoh Asano ,  Mark A. Skylar-Scott ,  Fei Chen ,  Paul W. Tillberg ,  Adam H. Marblestone ,  Edward S. Boyden

IPC分类号： C08J7/12 ,  C08J7/02 ,  B29C35/08 ,  C08J3/075 ,  C08J3/28 ,  B33Y80/00 ,  B29K105/00

摘要： The present invention enables three-dimensional nanofabrication by isotropic shrinking of patterned hydrogels. A hydrogel is first expanded, the rate of expansion being controlled by the concentration of the crosslinker. The hydrogel is then infused with a reactive group and patterned in three dimensions using a photon beam through a limited-diffraction microscope. Functional particles or materials are then deposited on the pattern. The hydrogel is then shrunk and cleaved from the pattern.

公开(公告)号：US20170081489A1

公开(公告)日：2017-03-23

申请号：US15261163

申请日：2016-09-09

申请人： Massachusetts Institute of Technology

发明人： Samuel G. Rodriques ,  Daniel Oran ,  Ruixuan Gao ,  Shoh Asano ,  Mark A. Skylar-Scott ,  Fei Chen ,  Paul W. Tillberg ,  Adam H. Marblestone ,  Edward S. Boyden

IPC分类号： C08J7/12 ,  C08J7/02 ,  B29C35/08 ,  C08J3/075

CPC分类号： C08J7/123 ,  B29C35/0805 ,  B29C2035/0838 ,  B29K2105/0061 ,  B33Y80/00 ,  C08J3/075 ,  C08J3/28 ,  C08J7/02 ,  C08J7/12 ,  C08J2333/26

摘要： The present invention enables three-dimensional nanofabrication by isotropic shrinking of patterned hydrogels. A hydrogel is first expanded, the rate of expansion being controlled by the concentration of the crosslinker. The hydrogel is then infused with a reactive group and patterned in three dimensions using a photon beam through a limited-diffraction microscope. Functional particles or materials are then deposited on the pattern. The hydrogel is then shrunk and cleaved from the pattern.