公开(公告)号：US20190212333A1

公开(公告)日：2019-07-11

申请号：US16113520

申请日：2018-08-27

Applicant: Massachusetts Institute of Technology

Inventor： Timothy M. Swager ,  Qifan Zhang ,  Suchol Savagatrup

IPC: G01N33/543 ,  G01N21/59 ,  C12Q1/6834 ,  G01N21/77

CPC classification number: G01N33/5432 ,  C12Q1/6834 ,  G01N21/59 ,  G01N21/77 ,  G01N33/54366 ,  G01N2021/7783 ,  C12Q2563/161

Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).

公开(公告)号：US12274993B2

公开(公告)日：2025-04-15

申请号：US16932392

申请日：2020-07-17

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Manning Swager ,  Jie Li ,  Suchol Savagatrup ,  Zachary P. Nelson ,  Kosuke Yoshinaga ,  Cassandra Zentner

IPC: B01L1/00 ,  B01J13/04 ,  B01J13/14 ,  C01B33/145 ,  G01N33/543

Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).

公开(公告)号：US12247945B2

公开(公告)日：2025-03-11

申请号：US16132336

申请日：2018-09-14

Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY ,  KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Timothy M. Swager ,  Suchol Savagatrup ,  Vera Schroder ,  Maggie He ,  Sibo Lin ,  Xi-Xiang Zhang ,  Khaled N. Salama

IPC: G01N27/414 ,  G01N27/30 ,  G01N27/48 ,  G01N33/00

Abstract: A sensor can include a redox-active complex. The sensor can be voltage sensitive.

公开(公告)号：US20210080456A1

公开(公告)日：2021-03-18

申请号：US16932392

申请日：2020-07-17

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Manning Swager ,  Jie Li ,  Suchol Savagatrup ,  Zachary P. Nelson ,  Kosuke Yoshinaga ,  Cassandra Zentner

IPC: G01N33/543 ,  G01N33/569

Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).

公开(公告)号：US20180080927A1

公开(公告)日：2018-03-22

申请号：US15269543

申请日：2016-09-19

Applicant: Massachusetts Institute of Technology

Inventor： Timothy M. Swager ,  Qifan Zhang ,  Suchol Savagatrup

IPC: G01N33/543 ,  G01N21/77 ,  C12Q1/68

CPC classification number: G01N33/5432 ,  C12Q1/6834 ,  G01N21/59 ,  G01N21/77 ,  G01N33/54366 ,  G01N2021/7783 ,  C12Q2563/161

Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).

公开(公告)号：US20190086360A1

公开(公告)日：2019-03-21

申请号：US16132336

申请日：2018-09-14

Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY ,  KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Timothy M. Swager ,  Suchol Savagatrup ,  Vera Schroder ,  Maggie He ,  Sibo Lin ,  Xi-Xiang Zhang ,  Khaled N. Salama

IPC: G01N27/414 ,  G01N27/30 ,  G01N27/48

Abstract: A sensor can include a redox-active complex. The sensor can be voltage sensitive.

公开(公告)号：US10060913B2

公开(公告)日：2018-08-28

申请号：US15269543

申请日：2016-09-19

Applicant: Massachusetts Institute of Technology

Inventor： Timothy M. Swager ,  Qifan Zhang ,  Suchol Savagatrup

IPC: G01N21/77 ,  G01N33/543 ,  C12Q1/6834

CPC classification number: G01N33/5432 ,  C12Q1/6834 ,  G01N21/59 ,  G01N21/77 ,  G01N33/54366 ,  G01N2021/7783 ,  C12Q2563/161

Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).