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1.发明申请MEDICAL DEVICE SYSTEM AND APPARATUS FOR GUIDING THE PLACEMENT OF A SUBCUTANEOUS DEVICE 审中-公开医疗装置系统及用于指导装置的装置公开(公告)号：US20100030230A1
公开(公告)日：2010-02-04
申请号：US12432052
申请日：2009-04-29
IPC分类号： A61B17/32
CPC分类号： A61B17/3468 , A61B17/3462 , A61B17/3472 , A61B2017/00026 , A61B2017/0003 , A61B2017/00561 , A61B2017/306 , A61B2017/320044 , A61B2017/320056 , A61M5/425 , A61M5/427 , A61M2005/1586 , A61N1/046 , A61N1/0504
摘要： A medical device system for guiding placement of a subcutaneous medical device that includes a strap extending along a length from a proximal end to a distal end, a first flange and a second flange extending along a portion of the length of the strap, a base portion extending along a portion of the length of the strap between the first flange and the second flange, an orientation member extending along the strap to limit a predetermined radius of curvature of the strap, and an indentation extending from the proximal end to the distal end of the strap, the indentation formed by the first flange, the second flange, and the base portion, wherein the first flange and the second flange include curved bottom portions that make contact with and compress a tissue layer to position the tissue layer within the indentation during the placement of the subcutaneous device.
摘要翻译： 一种用于引导皮下医疗装置的放置的医疗装置系统，该皮下医疗装置包括沿着从近端到远端的长度延伸的带，沿着带的长度的一部分延伸的第一凸缘和第二凸缘， 沿着所述带的长度的一部分延伸在所述第一凸缘和所述第二凸缘之间，定向构件沿着所述带延伸以限制所述带的预定曲率半径，以及从所述近端延伸到所述第二凸缘的远端 所述带，由所述第一凸缘，所述第二凸缘和所述基部形成的所述凹口，其中所述第一凸缘和所述第二凸缘包括弯曲的底部部分，所述弯曲底部部分与所述组织层接触并压缩所述组织层以将所述组织层定位在所述凹陷内 放置皮下装置。
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公开(公告)号：US08758365B2
公开(公告)日：2014-06-24
申请号：US13197156
申请日：2011-08-03
IPC分类号： A61B19/00
CPC分类号： A61N1/056 , A61N1/37205 , A61N1/3756
摘要： A guiding accessory, for use in conjunction with a guidewire and a catheter of an implant system, facilitates passage of an elongate and flexible conductor of a relatively compact therapy delivery device to an implant site, for example, within the cardiac venous system, when a therapy generator of the device is held within a distal portion of the catheter, and the catheter, device and guiding accessory are advanced along the guidewire. The guiding accessory includes a helically extending wall that forms a lumen within which the device conductor and guidewire extend. After advancing the catheter, guiding accessory and device to the implant site, the helically extending wall is unwound from around the device conductor, for removal, preferably, by pulling proximally on a tension line, which is attached to a proximal end of the wall.
摘要翻译： 用于与导线和植入物系统的导管一起使用的引导附件有助于使相对紧凑的治疗递送装置的细长柔性导体通过例如心脏静脉系统内的植入部位， 该装置的治疗发生器被保持在导管的远端部分内，并且导管，装置和导向附件沿着导丝线前进。 引导配件包括螺旋形延伸的壁，其形成设备导体和导丝延伸的管腔。 在推进导管之后，引导附件和装置到植入部位，螺旋形延伸的壁从装置导体周围展开，以便优选地通过在附着在壁的近端的张力线上向近侧拉动来移除。
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公开(公告)号：US20130035748A1
公开(公告)日：2013-02-07
申请号：US13197156
申请日：2011-08-03
IPC分类号： A61F2/84
CPC分类号： A61N1/056 , A61N1/37205 , A61N1/3756
摘要： A guiding accessory, for use in conjunction with a guidewire and a catheter of an implant system, facilitates passage of an elongate and flexible conductor of a relatively compact therapy delivery device to an implant site, for example, within the cardiac venous system, when a therapy generator of the device is held within a distal portion of the catheter, and the catheter, device and guiding accessory are advanced along the guidewire. The guiding accessory includes a helically extending wall that forms a lumen within which the device conductor and guidewire extend. After advancing the catheter, guiding accessory and device to the implant site, the helically extending wall is unwound from around the device conductor, for removal, preferably, by pulling proximally on a tension line, which is attached to a proximal end of the wall.
摘要翻译： 用于与导线和植入物系统的导管一起使用的引导附件有助于使相对紧凑的治疗递送装置的细长柔性导体通过例如心脏静脉系统内的植入部位， 该装置的治疗发生器被保持在导管的远端部分内，并且导管，装置和导向附件沿着导丝线前进。 引导配件包括螺旋形延伸的壁，其形成设备导体和导丝延伸的管腔。 在推进导管之后，引导附件和装置到植入部位，螺旋形延伸的壁从装置导体周围展开，以便优选地通过在附着在壁的近端的张力线上向近侧拉动来移除。
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4.发明授权Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries 有权通过有效拔除解剖学重新进行的低电压终止心律失常的方法公开(公告)号：US08175702B2
公开(公告)日：2012-05-08
申请号：US11266755
申请日：2005-11-03
IPC分类号： A61N1/00
CPC分类号： A61N1/3987 , A61B5/0402 , A61B5/0464 , A61B5/7239 , A61N1/3627 , A61N1/39 , A61N1/3906 , A61N1/3925 , A61N1/3962
摘要： A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed.
摘要翻译： 用于扑灭心律失常的方法利用解剖复位的折回波尖通过由相对低电压电场产生的去极化区域的破坏性干扰，以有效地解除解剖学折返。 优选地，相对低电压的电场通过至少一个比例如通过除颤阈值测试所建立的低于预期的脆弱性下限的绝对冲击来定义。 通过理解心脏细胞之间的电场分布的物理学，该方法允许输送足够的电场以解开再解剖核心的核心，无论确切的或估计的再入位置是已知的还是未知的，并且没有风险 诱导室颤。 公开了用于执行该方法的多个实施例。
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5.发明申请公开(公告)号：US20100030229A1
公开(公告)日：2010-02-04
申请号：US12432028
申请日：2009-04-29
IPC分类号： A61B17/00
CPC分类号： A61B17/3468 , A61B17/3462 , A61B17/3472 , A61B2017/00026 , A61B2017/0003 , A61B2017/00561 , A61B2017/306 , A61B2017/320044 , A61B2017/320056 , A61M5/425 , A61M5/427 , A61M2005/1586 , A61N1/046 , A61N1/0504
摘要： A medical device system for advancing a subcutaneous device to a desired implant site that includes a strap extending along a length from a proximal end to a distal end, a first flange and a second flange extending along a portion of the length of the strap, a base portion extending along a portion of the length of the strap between the first flange and the second flange, and an indentation extending from the proximal end to the distal end of the strap, the indentation formed by the first flange, the second flange, and the base portion, wherein the first flange and the second flange include curved bottom portions that make contact with and compress a tissue layer to position the tissue layer within the indentation during the placement of the subcutaneous device.
摘要翻译： 一种用于将皮下装置推进到期望的植入部位的医疗装置系统，所述植入部位包括沿着从近端到远端的长度延伸的带，沿着带的长度的一部分延伸的第一凸缘和第二凸缘， 所述基部沿着所述带的所述长度的第一凸缘和所述第二凸缘之间的部分延伸，以及从所述带的近端延伸到所述远端，所述凹陷由所述第一凸缘，所述第二凸缘和 所述基部部分，其中所述第一凸缘和所述第二凸缘包括弯曲的底部部分，所述弯曲的底部部分在所述皮下装置的放置期间与所述组织层接触并将所述组织层定位在所述凹陷内。
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6.发明授权Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries 有权通过有效拔除解剖学重新进行的低电压终止心律失常的方法公开(公告)号：US08639325B2
公开(公告)日：2014-01-28
申请号：US13464537
申请日：2012-05-04
IPC分类号： A61N1/00
CPC分类号： A61N1/3987 , A61B5/0402 , A61B5/0464 , A61B5/7239 , A61N1/3627 , A61N1/39 , A61N1/3906 , A61N1/3925 , A61N1/3962
摘要： A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed.
摘要翻译： 用于扑灭心律失常的方法利用解剖复位的折回波尖通过由相对低电压电场产生的去极化区域的破坏性干扰，以有效地解除解剖学折返。 优选地，相对低电压的电场通过至少一个比例如通过除颤阈值测试所建立的低于预期的脆弱性下限的绝对冲击来定义。 通过理解心脏细胞之间的电场分布的物理学，该方法允许输送足够的电场以解开再解剖核心的核心，无论确切的或估计的再入位置是已知的还是未知的，并且没有风险 诱导室颤。 公开了用于执行该方法的多个实施例。
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7.发明申请公开(公告)号：US20090177242A1
公开(公告)日：2009-07-09
申请号：US11969663
申请日：2008-01-04
申请人： Vladimir P. Nikolski , William J. Havel , Joseph L. Sullivan , Daniel W. Piraino , Eric R. Williams
发明人： Vladimir P. Nikolski , William J. Havel , Joseph L. Sullivan , Daniel W. Piraino , Eric R. Williams
IPC分类号： A61N1/39
CPC分类号： A61N1/39 , A61N1/3943 , A61N1/3962
摘要： An apparatus and method for delivering an external shock pulse receive pacing pulses generated by a first device and a shock pulse generated by a second device. An output of the apparatus is coupled to patient electrodes and the apparatus controls delivery of the received pacing pulses to the output and delivery of the received shock pulse to the output. A control module, pacing control and shock control included in the apparatus cooperatively control delivery of the received shock pulse to the output at a predetermined delay after one of the received pacing pulses.
摘要翻译： 用于递送外部冲击脉冲的装置和方法接收由第一装置产生的起搏脉冲和由第二装置产生的冲击脉冲。 该装置的输出耦合到患者电极，并且该装置控制所接收的起搏脉冲的输出到接收的冲击脉冲的输出和输出。 装置中包括的控制模块，起搏控制和冲击控制协调地控制接收到的冲击脉冲在一个接收到的起搏脉冲之后以预定延迟输出到输出端。
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8.发明授权Medical device system and apparatus for guiding the placement of a subcutaneous device 有权用于引导皮下装置的放置的医疗装置系统和装置公开(公告)号：US08998929B2
公开(公告)日：2015-04-07
申请号：US12432028
申请日：2009-04-29
CPC分类号： A61B17/3468 , A61B17/3462 , A61B17/3472 , A61B2017/00026 , A61B2017/0003 , A61B2017/00561 , A61B2017/306 , A61B2017/320044 , A61B2017/320056 , A61M5/425 , A61M5/427 , A61M2005/1586 , A61N1/046 , A61N1/0504
摘要： A medical device system for advancing a subcutaneous device to a desired implant site that includes a strap extending along a length from a proximal end to a distal end, a first flange and a second flange extending along a portion of the length of the strap, a base portion extending along a portion of the length of the strap between the first flange and the second flange, and an indentation extending from the proximal end to the distal end of the strap, the indentation formed by the first flange, the second flange, and the base portion, wherein the first flange and the second flange include curved bottom portions that make contact with and compress a tissue layer to position the tissue layer within the indentation during the placement of the subcutaneous device.
摘要翻译： 一种用于将皮下装置推进到期望的植入部位的医疗装置系统，所述植入部位包括沿着从近端到远端的长度延伸的带，沿着带的长度的一部分延伸的第一凸缘和第二凸缘， 所述基部沿着所述带的所述长度的第一凸缘和所述第二凸缘之间的部分延伸，以及从所述带的近端延伸到所述远端，所述凹陷由所述第一凸缘，所述第二凸缘和 所述基部部分，其中所述第一凸缘和所述第二凸缘包括弯曲的底部部分，所述弯曲的底部部分在所述皮下装置的放置期间与所述组织层接触并将所述组织层定位在所述凹陷内。
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公开(公告)号：US08391973B2
公开(公告)日：2013-03-05
申请号：US11969663
申请日：2008-01-04
申请人： Vladimir P. Nikolski , William J. Havel , Joseph L. Sullivan , Daniel W. Piraino , Eric R. Williams
发明人： Vladimir P. Nikolski , William J. Havel , Joseph L. Sullivan , Daniel W. Piraino , Eric R. Williams
IPC分类号： A61N1/39
CPC分类号： A61N1/39 , A61N1/3943 , A61N1/3962
摘要： An apparatus and method for delivering an external shock pulse receive pacing pulses generated by a first device and a shock pulse generated by a second device. An output of the apparatus is coupled to patient electrodes and the apparatus controls delivery of the received pacing pulses to the output and delivery of the received shock pulse to the output. A control module, pacing control and shock control included in the apparatus cooperatively control delivery of the received shock pulse to the output at a predetermined delay after one of the received pacing pulses.
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10.发明申请METHOD FOR LOW-VOLTAGE TERMINATION OF CARDIAC ARRHYTHMIAS BY EFFECTIVELY UNPINNING ANATOMICAL REENTRIES 有权通过有效的解剖解剖学方法对心脏性心律失常的低电压终止公开(公告)号：US20130013012A1
公开(公告)日：2013-01-10
申请号：US13464537
申请日：2012-05-04
IPC分类号： A61N1/39
CPC分类号： A61N1/3987 , A61B5/0402 , A61B5/0464 , A61B5/7239 , A61N1/3627 , A61N1/39 , A61N1/3906 , A61N1/3925 , A61N1/3962
摘要： A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed.
摘要翻译： 用于扑灭心律失常的方法利用解剖复位的折回波尖通过由相对低电压电场产生的去极化区域的破坏性干扰，以有效地解除解剖学折返。 优选地，相对低电压的电场通过至少一个比例如通过除颤阈值测试所建立的低于预期的脆弱性下限的绝对冲击来定义。 通过理解心脏细胞之间的电场分布的物理学，该方法允许输送足够的电场以解开再解剖核心的核心，无论确切的或估计的再入位置是已知的还是未知的，并且没有风险 诱导室颤。 公开了用于执行该方法的多个实施例。
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