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公开(公告)号：US20120330377A1
公开(公告)日：2012-12-27
申请号：US13590011
申请日：2012-08-20
申请人： Matthew J. McMahon , Arup Roy , Scott Greenwald , Ione Fine , Alan Matthew Horsager , Avraham I. Caspi , Kelly Hobart McClure , Robert Jay Greenberg
发明人： Matthew J. McMahon , Arup Roy , Scott Greenwald , Ione Fine , Alan Matthew Horsager , Avraham I. Caspi , Kelly Hobart McClure , Robert Jay Greenberg
摘要： The present invention is a fitting system with a graphical interface with specific interface screens for specific functions. Methods and devices for fitting a visual prosthesis are described. In one of the methods, threshold levels and maximum levels for the electrodes of the prosthesis are determined and a map of brightness to electrode stimulation levels is later formed. A fitting system for a visual prosthesis is also discussed, together with a computer-operated system having a graphical user interface showing visual prosthesis diagnostic screens and visual prosthesis configuration screens.
摘要翻译： 本发明是具有特定功能的特定接口屏幕的图形界面的拟合系统。 描述了用于装配视觉假体的方法和装置。 在其中一种方法中，确定假体电极的阈值水平和最大水平，并且稍后形成亮度与电极刺激水平的图。 还讨论了用于视觉假体的装配系统，以及具有显示视觉假体诊断屏幕和视觉假体配置屏幕的图形用户界面的计算机操作系统。
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公开(公告)号：US10780272B2
公开(公告)日：2020-09-22
申请号：US13590011
申请日：2012-08-20
申请人： Matthew J. McMahon , Arup Roy , Scott Greenwald , Ione Fine , Alan Matthew Horsager , Avraham I. Caspi , Kelly Hobart McClure , Robert Jay Greenberg
发明人： Matthew J. McMahon , Arup Roy , Scott Greenwald , Ione Fine , Alan Matthew Horsager , Avraham I. Caspi , Kelly Hobart McClure , Robert Jay Greenberg
摘要： The present invention is a fitting system with a graphical interface with specific interface screens for specific functions. Methods and devices for fitting a visual prosthesis are described. In one of the methods, threshold levels and maximum levels for the electrodes of the prosthesis are determined and a map of brightness to electrode stimulation levels is later formed. A fitting system for a visual prosthesis is also discussed, together with a computer-operated system having a graphical user interface showing visual prosthesis diagnostic screens and visual prosthesis configuration screens.
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公开(公告)号：US08271091B2
公开(公告)日：2012-09-18
申请号：US11796425
申请日：2007-04-27
申请人： Matthew J. McMahon , Arup Roy , Scott Greenwald , Ione Fine , Alan Matthew Horsager , Avraham I. Caspi , Kelly Hobart McClure , Robert Jay Greenberg
发明人： Matthew J. McMahon , Arup Roy , Scott Greenwald , Ione Fine , Alan Matthew Horsager , Avraham I. Caspi , Kelly Hobart McClure , Robert Jay Greenberg
IPC分类号： A61N1/08
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/37247
摘要： Methods and devices for fitting a visual prosthesis are described. In one of the methods, threshold levels and maximum levels for the electrodes of the prosthesis are determined and a map of brightness to electrode stimulation levels is later formed. A fitting system for a visual prosthesis is also discussed, together with a computer-operated system having a graphical user interface showing visual prosthesis diagnostic screens and visual prosthesis configuration screens.
摘要翻译： 描述了用于装配视觉假体的方法和装置。 在其中一种方法中，确定假体电极的阈值水平和最大水平，并且稍后形成亮度与电极刺激水平的图。 还讨论了用于视觉假体的装配系统，以及具有显示视觉假体诊断屏幕和视觉假体配置屏幕的图形用户界面的计算机操作系统。
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公开(公告)号：US07908011B2
公开(公告)日：2011-03-15
申请号：US11927258
申请日：2007-10-29
申请人： Matthew J. McMahon , Arup Roy , Scott Greenwald , Ione Fine , Alan Matthew Horsager , Avraham I. Caspi , Kelly Hobart McClure , Robert Jay Greenberg
发明人： Matthew J. McMahon , Arup Roy , Scott Greenwald , Ione Fine , Alan Matthew Horsager , Avraham I. Caspi , Kelly Hobart McClure , Robert Jay Greenberg
IPC分类号： A61N1/08
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/37247
摘要： Methods and devices for fitting a visual prosthesis are described. In one of the methods, threshold levels and maximum levels for the electrodes of the prosthesis are determined and a map of brightness to electrode stimulation levels is later formed. A fitting system for a visual prosthesis is also discussed, together with a computer-operated system having a graphical user interface showing visual prosthesis diagnostic screens and visual prosthesis configuration screens.
摘要翻译： 描述了用于装配视觉假体的方法和装置。 在其中一种方法中，确定假体电极的阈值水平和最大水平，并且稍后形成亮度与电极刺激水平的图。 还讨论了用于视觉假体的装配系统，以及具有显示视觉假体诊断屏幕和视觉假体配置屏幕的图形用户界面的计算机操作系统。
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公开(公告)号：US09078739B2
公开(公告)日：2015-07-14
申请号：US12879979
申请日：2010-09-10
申请人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
发明人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and The response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
摘要翻译： 本发明是一种将电极阵列自动调整为单个患者的神经特征的方法。 对电神经刺激的感知反应因患者而异，并且对电神经刺激的响应因患者而异，并且电流和感知亮度之间的关系通常是非线性的。 需要确定这种关系以适应每个患者的假体设置。 将感知反应映射到刺激是有利的。 本发明的映射方法是提供在电流，电压，脉冲持续时间，频率或某些其他维度上变化的多个刺激; 测量和记录对这些刺激的反应; 从各个点得出描述地图的公式或方程; 存储公式; 并使用该公式来映射未来的刺激。
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公开(公告)号：US07738962B2
公开(公告)日：2010-06-15
申请号：US11357680
申请日：2006-02-16
申请人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
发明人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and The response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
摘要翻译： 本发明是一种将电极阵列自动调整为单个患者的神经特征的方法。 对电神经刺激的感知反应因患者而异，并且对电神经刺激的响应因患者而异，并且电流和感知亮度之间的关系通常是非线性的。 需要确定这种关系以适应每个患者的假体设置。 将感知反应映射到刺激是有利的。 本发明的映射方法是提供在电流，电压，脉冲持续时间，频率或某些其他维度上变化的多个刺激; 测量和记录对这些刺激的反应; 从各个点得出描述地图的公式或方程; 存储公式; 并使用该公式来映射未来的刺激。
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公开(公告)号：US20080188908A1
公开(公告)日：2008-08-07
申请号：US11924334
申请日：2007-10-25
申请人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
发明人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
IPC分类号： A61N1/08
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and The response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
摘要翻译： 本发明是一种将电极阵列自动调整为单个患者的神经特征的方法。 对电神经刺激的感知反应因患者而异，并且对电神经刺激的响应因患者而异，并且电流和感知亮度之间的关系通常是非线性的。 需要确定这种关系以适应每个患者的假体设置。 将感知反应映射到刺激是有利的。 本发明的映射方法是提供在电流，电压，脉冲持续时间，频率或某些其他维度上变化的多个刺激; 测量和记录对这些刺激的反应; 从各个点得出描述地图的公式或方程; 存储公式; 并使用该公式来映射未来的刺激。
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公开(公告)号：US07818064B2
公开(公告)日：2010-10-19
申请号：US11924334
申请日：2007-10-25
申请人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
发明人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
IPC分类号： A61N1/36
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and the response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
摘要翻译： 本发明是一种将电极阵列自动调整为单个患者的神经特征的方法。 对电神经刺激的感知反应因患者而异，并且对电神经刺激的响应随病人而变化，并且电流和感知亮度之间的关系通常是非线性的。 需要确定这种关系以适应每个患者的假体设置。 将感知反应映射到刺激是有利的。 本发明的映射方法是提供在电流，电压，脉冲持续时间，频率或某些其他维度上变化的多个刺激; 测量和记录对这些刺激的反应; 从各个点得出描述地图的公式或方程; 存储公式; 并使用该公式来映射未来的刺激。
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公开(公告)号：US20110015699A1
公开(公告)日：2011-01-20
申请号：US12879979
申请日：2010-09-10
申请人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
发明人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
IPC分类号： A61N1/36
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and The response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
摘要翻译： 本发明是一种将电极阵列自动调整为单个患者的神经特征的方法。 对电神经刺激的感知反应因患者而异，并且对电神经刺激的响应因患者而异，并且电流和感知亮度之间的关系通常是非线性的。 需要确定这种关系以适应每个患者的假体设置。 将感知反应映射到刺激是有利的。 本发明的映射方法是提供在电流，电压，脉冲持续时间，频率或某些其他维度上变化的多个刺激; 测量和记录对这些刺激的反应; 从各个点得出描述地图的公式或方程; 存储公式; 并使用该公式来映射未来的刺激。
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公开(公告)号：US09974953B2
公开(公告)日：2018-05-22
申请号：US13430356
申请日：2012-03-26
申请人： Robert Jay Greenberg , Kelly Hobart McClure , James Singleton Little , Rongqing Dai , Arup Roy , Richard Agustin Castro , John Reinhold , Kea-Tiong Tang , Sumit Yadav , Chunhong Zhou , Dao Min Zhou , Pishoy Maksy
发明人： Robert Jay Greenberg , Kelly Hobart McClure , James Singleton Little , Rongqing Dai , Arup Roy , Richard Agustin Castro , John Reinhold , Kea-Tiong Tang , Sumit Yadav , Chunhong Zhou , Dao Min Zhou , Pishoy Maksy
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/0551 , A61N1/08 , A61N1/36142 , A61N1/36185
摘要： An apparatus for controlling the stimulation of neural tissue which includes a neural stimulator, an input device for providing input to the neural stimulator for neural stimulation, at least one electrode electrically connected to and driven by the neural stimulator and suitable to stimulate neural tissue, a device capable of determining a charge per phase by calculating a discrete integral of the wave form of the input for the at least one electrode, a calculating device for comparing the charge per phase to a predetermined maximum and determining a reduced stimulation for the at least one electrode by the amount necessary not to exceed the predetermined maximum for the at least one electrode, and a current pulse generator for stimulating the neural tissue according to the reduced stimulation level.
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