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公开(公告)号：US07662917B2
公开(公告)日：2010-02-16
申请号：US10529655
申请日：2003-09-30
发明人： Matthew J. Scanlan , Sang-Yull Lee , Lloyd J. Old
IPC分类号： C07K14/00
CPC分类号： C07K14/4748 , A61K38/00 , G01N33/57488 , Y10T436/143333
摘要： The invention relates to sarcoma-associated antigens and the nucleic acid molecules that encode them. The invention further relates to the use of the nucleic acid molecules, polypeptides and fragments thereof associated with sarcoma in methods and compositions for the diagnosis and treatment of diseases, such as cancer. More specifically, the invention relates to the discovery of a novel cancer/testis (CT) antigen, NY-SAR-35.
摘要翻译： 本发明涉及肉瘤相关抗原和编码它们的核酸分子。 本发明进一步涉及与肉瘤相关的核酸分子，多肽及其片段在用于诊断和治疗诸如癌症的疾病的方法和组合物中的用途。 更具体地，本发明涉及新型癌/睾丸（CT）抗原NY-SAR-35的发现。
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公开(公告)号：US08252903B2
公开(公告)日：2012-08-28
申请号：US12683374
申请日：2010-01-06
发明人： Matthew J. Scanlan , Sang-Yull Lee , Lloyd J. Old
CPC分类号： C07K14/4748 , A61K38/00 , G01N33/57488 , Y10T436/143333
摘要： The invention relates to sarcoma-associated antigens and the nucleic acid molecules that encode them. The invention further relates to the use of the nucleic acid molecules, polypeptides and fragments thereof associated with sarcoma in methods and compositions for the diagnosis and treatment of diseases, such as cancer. More specifically, the invention relates to the discovery of a novel cancer/testis (CT) antigen, NY-SAR-35.
摘要翻译： 本发明涉及肉瘤相关抗原和编码它们的核酸分子。 本发明进一步涉及与肉瘤相关的核酸分子，多肽及其片段在用于诊断和治疗诸如癌症的疾病的方法和组合物中的用途。 更具体地，本发明涉及新型癌/睾丸（CT）抗原NY-SAR-35的发现。
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公开(公告)号：US20080089888A1
公开(公告)日：2008-04-17
申请号：US10529655
申请日：2003-09-30
IPC分类号： A61K39/395 , A61P35/00 , C07H21/00 , C07K14/00 , C07K16/30 , C12N1/00 , C12N15/63 , G01N33/53 , G01N33/574
CPC分类号： C07K14/4748 , A61K38/00 , G01N33/57488 , Y10T436/143333
摘要： The invention relates to sarcoma-associated antigens and the nucleic acid molecules that encode them. The invention further relates to the use of the nucleic acid molecules, polypeptides and fragments thereof associated with sarcoma in methods and compositions for the diagnosis and treatment of diseases, such as cancer. More specifically, the invention relates to the discovery of a novel cancer/testis (CT) antigen, NY-SAR-35.
摘要翻译： 本发明涉及肉瘤相关抗原和编码它们的核酸分子。 本发明进一步涉及与肉瘤相关的核酸分子，多肽及其片段在用于诊断和治疗诸如癌症的疾病的方法和组合物中的用途。 更具体地，本发明涉及新型癌/睾丸（CT）抗原NY-SAR-35的发现。
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公开(公告)号：US07560537B2
公开(公告)日：2009-07-14
申请号：US10260708
申请日：2002-09-30
申请人： Matthew J. Scanlan , Sang-Yull Lee , Lloyd J. Old
发明人： Matthew J. Scanlan , Sang-Yull Lee , Lloyd J. Old
IPC分类号： C07H21/02
CPC分类号： C07K14/4748 , C07H21/04 , C07K16/30 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , G01N33/57488
摘要： The invention relates to sarcoma-associated antigens and the nucleic acid molecules that encode them. The invention further relates to the use of the nucleic acid molecules, polypeptides and fragments thereof associated with sarcoma in methods and compositions for the diagnosis and treatment of diseases, such as cancer. More specifically, the invention relates to the discovery of a novel cancer/testis (CT) antigen, NY-SAR-35.
摘要翻译： 本发明涉及肉瘤相关抗原和编码它们的核酸分子。 本发明进一步涉及与肉瘤相关的核酸分子，多肽及其片段在用于诊断和治疗诸如癌症的疾病的方法和组合物中的用途。 更具体地，本发明涉及新型癌/睾丸（CT）抗原NY-SAR-35的发现。
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公开(公告)号：US20100172910A1
公开(公告)日：2010-07-08
申请号：US12683374
申请日：2010-01-06
IPC分类号： A61K39/395 , C07K16/00 , G01N33/53 , A61P35/00
CPC分类号： C07K14/4748 , A61K38/00 , G01N33/57488 , Y10T436/143333
摘要： The invention relates to sarcoma-associated antigens and the nucleic acid molecules that encode them. The invention further relates to the use of the nucleic acid molecules, polypeptides and fragments thereof associated with sarcoma in methods and compositions for the diagnosis and treatment of diseases, such as cancer. More specifically, the invention relates to the discovery of a novel cancer/testis (CT) antigen, NY-SAR-35.
摘要翻译： 本发明涉及肉瘤相关抗原和编码它们的核酸分子。 本发明进一步涉及与肉瘤相关的核酸分子，多肽及其片段在用于诊断和治疗诸如癌症的疾病的方法和组合物中的用途。 更具体地，本发明涉及新型癌/睾丸（CT）抗原NY-SAR-35的发现。
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6.发明授权Isolated nucleic acid molecules associated with colon, renal, and stomach cancer and methods of using these 失效与结肠，肾和胃癌相关的分离的核酸分子及其使用方法公开(公告)号：US06403373B1
公开(公告)日：2002-06-11
申请号：US09102322
申请日：1998-06-22
IPC分类号： C12N510
CPC分类号： G01N33/56977 , A61K38/00 , C07K14/4748 , C12Q1/6886 , C12Q2600/158 , G01N33/5748
摘要： Various molecules associated with cancer are disclosed. The invention also discloses diagnostic and therapeutic methods based upon these molecules.
摘要翻译： 公开了与癌症相关的各种分子。 本发明还公开了基于这些分子的诊断和治疗方法。
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公开(公告)号：US06339140B1
公开(公告)日：2002-01-15
申请号：US09796780
申请日：2001-03-01
申请人： Ali O. Gure , Ozlem Tureci , Ugur Sahin , Solam Tsang , Matthew J. Scanlan , Alexander Knuth , Michael Pfreundschuh , Lloyd J. Old , Yao-Tseng Chen
发明人： Ali O. Gure , Ozlem Tureci , Ugur Sahin , Solam Tsang , Matthew J. Scanlan , Alexander Knuth , Michael Pfreundschuh , Lloyd J. Old , Yao-Tseng Chen
IPC分类号： C07K100
CPC分类号： C07K14/47
摘要： The invention relates to members of the SSX family of genes, as well as their uses.
摘要翻译： 本发明涉及SSX家族基因的成员及其用途
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公开(公告)号：US20110177079A1
公开(公告)日：2011-07-21
申请号：US11662322
申请日：2005-09-08
申请人： Yao-Tseng Chen , Lloyd J. Old , Andrew J.G. Simpson , Victor C. Jongeneel , Matthew J. Scanlan , Cynthia H. Scanlan
发明人： Yao-Tseng Chen , Lloyd J. Old , Andrew J.G. Simpson , Victor C. Jongeneel , Matthew J. Scanlan , Cynthia H. Scanlan
IPC分类号： A61K39/395 , A61K39/00 , C07K14/435 , G01N33/574 , C12N15/12 , A61P35/00
CPC分类号： A61K39/0011 , A61K38/00 , A61K2039/505 , C07K14/4748 , G01N33/574
摘要： The invention relates to cancer-testis antigens and the nucleic acid molecules that encode them. The invention further relates to the use of the nucleic acid molecules, polypeptides and fragments thereof in methods and compositions for the diagnosis and treatment of diseases, such as cancer. More specifically, the invention relates to the discovery of novel cancer-testis (CT) antigens.
摘要翻译： 本发明涉及癌 - 睾丸抗原和编码它们的核酸分子。 本发明还涉及用于诊断和治疗诸如癌症的疾病的方法和组合物中核酸分子，多肽和其片段的用途。 更具体地，本发明涉及新型癌 - 睾丸（CT）抗原的发现。
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公开(公告)号：US07335467B2
公开(公告)日：2008-02-26
申请号：US10146473
申请日：2002-05-15
申请人： Matthew J. Scanlan , Ivan Gout , Elisabeth Stockert , Lloyd J. Old , Ali Gure , Yao-Tseng Chen
发明人： Matthew J. Scanlan , Ivan Gout , Elisabeth Stockert , Lloyd J. Old , Ali Gure , Yao-Tseng Chen
IPC分类号： C12Q1/00 , C12Q1/68 , G01N33/567 , G01N33/574 , G01N1/00 , G01N33/48 , C12P19/34
CPC分类号： G01N33/57415 , C12Q1/6886 , C12Q2600/158 , Y10T436/25
摘要： The invention provides methods for diagnosing cancer including breast cancer, based on the identification of certain breast cancer-associated polypeptides as antigens that elicit immune responses in breast cancer. The identified antigens can be utilized as markers for diagnosing breast cancer, and for following the course of treatment of breast cancer.
摘要翻译： 本发明提供了鉴定某些乳腺癌相关多肽作为在乳腺癌中引起免疫反应的抗原来诊断包括乳腺癌在内的癌症的方法。 鉴定的抗原可用作诊断乳腺癌的标志物，并用于跟踪乳腺癌的治疗过程。
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10.发明授权Isolated nucleic acid molecules associated with colon cancer and methods for diagnosing and treating colon cancer 失效与结肠癌相关的分离的核酸分子以及诊断和治疗结肠癌的方法
公开(公告)号：US6043084A
公开(公告)日：2000-03-28
申请号：US948705
申请日：1997-10-10
IPC分类号： A61K38/00 , C07K14/47 , C12N15/12 , C12Q1/68 , G01N33/569 , G01N33/574 , C12N5/10 , C12N15/63
CPC分类号： C07K14/4748 , C12Q1/6886 , G01N33/56977 , G01N33/5748 , A61K38/00
摘要： Various molecules associated with disorders such as colon cancer are disclosed. The invention also discloses diagnostic and therapeutic methods based upon these molecules.
摘要翻译： 公开了与诸如结肠癌的疾病相关的各种分子。 本发明还公开了基于这些分子的诊断和治疗方法。
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