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    Drug-enhanced adhesion prevention
    6.
    发明授权
    Drug-enhanced adhesion prevention 有权
    药物增强粘附防止

    公开(公告)号：US09066912B2

    公开(公告)日：2015-06-30

    申请号：US10714719

    申请日：2003-11-17

    申请人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61K9/127 ,  A61K31/196 ,  A61K9/50

    CPC分类号： A61K31/196 ,  A61K9/127 ,  A61K9/5031

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Tranilast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括以体积的量向管腔内的组织表面直接给予Tranilast或其类似物 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。

    Drug-enhanced adhesion prevention
    8.
    发明授权
    Drug-enhanced adhesion prevention 有权
    药物增强粘附防止

    公开(公告)号：US08394399B2

    公开(公告)日：2013-03-12

    申请号：US12021546

    申请日：2008-01-29

    申请人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61F2/02

    CPC分类号： A61K9/1647

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Pemirolast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括将Pemirolast或其类似物以体积的数量直接施用于体腔内的组织表面 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。

    METHOD OF TREATMENT FOR OSTEOARTHRITIS BY LOCAL INTRA-ARTICULAR INJECTION OF MICROPARTICLES
    9.
    发明申请
    METHOD OF TREATMENT FOR OSTEOARTHRITIS BY LOCAL INTRA-ARTICULAR INJECTION OF MICROPARTICLES 审中-公开
    通过局部注射微量元素治疗骨质疏松症的方法

    公开(公告)号：US20100016257A1

    公开(公告)日：2010-01-21

    申请号：US12564237

    申请日：2009-09-22

    申请人： Laura J. Brown ,  Han Cui ,  Zhangwen Wu

    发明人： Laura J. Brown ,  Han Cui ,  Zhangwen Wu

    IPC分类号： A61K31/728 ,  A61P19/02

    CPC分类号： A61K9/0019 ,  A61K9/1641

    摘要： A method of treatment of osteoarthritis is described, where a therapeutically effective amount of a composition having biodegradable microparticles in an aqueous vehicle is delivered into the intra-articular space of a joint. In one aspect, the microparticle-containing composition is injected into the synovial fluid-containing portion of an affected joint.

    摘要翻译： 描述了治疗骨关节炎的方法，其中在水性载体中具有可生物降解的微粒的组合物的治疗有效量被递送到关节的关节内空间。 一方面，将含有微粒的组合物注入受影响的关节的含滑液的部分。

    DRUG-ENHANCED ADHESION PREVENTION
    10.
    发明申请
    DRUG-ENHANCED ADHESION PREVENTION 有权
    增强粘合剂预防

    公开(公告)号：US20080119494A1

    公开(公告)日：2008-05-22

    申请号：US12021546

    申请日：2008-01-29

    申请人： Janel Young ,  Scott Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel Young ,  Scott Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61K31/519 ,  A61P41/00

    CPC分类号： A61K9/1647

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Pemirolast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括将Pemirolast或其类似物以体积的数量直接施用于体腔内的组织表面 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。