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公开(公告)号：US12064631B2
公开(公告)日：2024-08-20
申请号：US17100384
申请日：2020-11-20
申请人： Medtronic, Inc.
IPC分类号： A61N1/36
CPC分类号： A61N1/36139 , A61N1/36062 , A61N1/36153 , A61N1/36171 , A61N1/36175
摘要： Systems, devices, and techniques for adjusting electrical stimulation based on a posture state of a patient are described. For example, a system may include sensing circuitry configured to sense an ECAP signal and processing circuitry configured to control delivery of the electrical stimulation to a patient according to a first value of a stimulation parameter and determine a characteristic value of the ECAP signal. The processing circuitry may also be configured to receive, from a sensor, a posture state signal representing a posture state of the patient, determine, based on the posture state signal, a gain value for the stimulation parameter, adjust, based on the characteristic value of the ECAP signal and the gain value, the first value of the stimulation parameter to a second value of the stimulation parameter, and control delivery of the electrical stimulation according to the second value of the stimulation parameter.
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公开(公告)号：US20240091539A1
公开(公告)日：2024-03-21
申请号：US18257076
申请日：2022-01-13
申请人： Medtronic, Inc.
IPC分类号： A61N1/36
CPC分类号： A61N1/36139 , A61N1/36171 , A61N1/36178
摘要： Systems, devices, and techniques for adjusting electrical stimulation based on sensed ECAP signals. For example, processing circuitry is configured to control delivery of a first train of electrical stimulation pulses at a first frequency to a first target tissue and control delivery of a second train of electrical stimulation pulses at a second frequency to a second target tissue different from the first target tissue. The processing circuitry can also receive an ECAP signal elicited by a pulse of the second train of electrical stimulation pulses, adjust, based on the ECAP signal, a first value of a parameter that at least partially defines the first tram of electrical stimulation pulses to a second value, and, responsive to adjusting the first value of the parameter to the second value, control delivery of subsequent pulses of the first tram of electrical stimulation pulses according to the second value of the parameter.
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公开(公告)号：US11129991B2
公开(公告)日：2021-09-28
申请号：US16449168
申请日：2019-06-21
申请人： Medtronic, Inc.
发明人： David A. Dinsmoor , Kristin N. Hageman , Hank Bink
IPC分类号： A61N1/36
摘要： Devices, systems, and techniques for controlling electrical stimulation therapy are described. In one example, a system may be configured to deliver electrical stimulation therapy to a patient, the electrical stimulation therapy comprising a plurality of therapy pulses at a predetermined pulse frequency over a period of time and deliver, over the period of time, a plurality of control pulses interleaved with at least some therapy pulses of the plurality of therapy pulses. The system may also be configured to sense, after one or more control pulses and prior to an immediately subsequent therapy pulse of the plurality of therapy pulses, a respective evoked compound action potential (ECAP), adjust, based on at least one respective ECAP, one or more parameter values that at least partially defines the plurality of therapy pulses, and deliver the electrical stimulation therapy to the patient according to the adjusted one or more parameter values.
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公开(公告)号：US20210187302A1
公开(公告)日：2021-06-24
申请号：US17100384
申请日：2020-11-20
申请人： Medtronic, Inc.
IPC分类号： A61N1/36
摘要： Systems, devices, and techniques for adjusting electrical stimulation based on a posture state of a patient are described. For example, a system may include sensing circuitry configured to sense an ECAP signal and processing circuitry configured to control delivery of the electrical stimulation to a patient according to a first value of a stimulation parameter and determine a characteristic value of the ECAP signal. The processing circuitry may also be configured to receive, from a sensor, a posture state signal representing a posture state of the patient, determine, based on the posture state signal, a gain value for the stimulation parameter, adjust, based on the characteristic value of the ECAP signal and the gain value, the first value of the stimulation parameter to a second value of the stimulation parameter, and control delivery of the electrical stimulation according to the second value of the stimulation parameter.
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公开(公告)号：US20210187300A1
公开(公告)日：2021-06-24
申请号：US16721576
申请日：2019-12-19
申请人： Medtronic, Inc.
IPC分类号： A61N1/36 , A61B5/11 , A61B5/0488
摘要： Systems, devices, and techniques are described for determining a posture state of a patient based on detected evoked compound action potentials (ECAPs). In one example, a medical device includes stimulation circuitry configured to deliver electrical stimulation and sensing circuitry configured to sense a plurality of evoked compound action potential (ECAP) signals. The medical device also includes processing circuitry configured to control the stimulation circuitry to deliver a plurality of electrical stimulation pulses having different amplitude values, control the sensing circuitry to detect, after delivery of each electrical stimulation pulse of the plurality of electrical stimulation pulses, a respective ECAP signal of the plurality of ECAP signals, and determine, based on the plurality of ECAP signals, a posture state of the patient.
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公开(公告)号：US20190388695A1
公开(公告)日：2019-12-26
申请号：US16449168
申请日：2019-06-21
申请人： Medtronic, Inc.
发明人： David A. Dinsmoor , Kristin N. Hageman , Hank Bink
IPC分类号： A61N1/36
摘要： Devices, systems, and techniques for controlling electrical stimulation therapy are described. In one example, a system may be configured to deliver electrical stimulation therapy to a patient, the electrical stimulation therapy comprising a plurality of therapy pulses at a predetermined pulse frequency over a period of time and deliver, over the period of time, a plurality of control pulses interleaved with at least some therapy pulses of the plurality of therapy pulses. The system may also be configured to sense, after one or more control pulses and prior to an immediately subsequent therapy pulse of the plurality of therapy pulses, a respective evoked compound action potential (ECAP), adjust, based on at least one respective ECAP, one or more parameter values that at least partially defines the plurality of therapy pulses, and deliver the electrical stimulation therapy to the patient according to the adjusted one or more parameter values.
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公开(公告)号：US12011595B2
公开(公告)日：2024-06-18
申请号：US17100455
申请日：2020-11-20
申请人： Medtronic, Inc.
IPC分类号： A61N1/36
CPC分类号： A61N1/36062 , A61N1/36139 , A61N1/36153 , A61N1/36192
摘要： Systems, devices, and techniques for adjusting electrical stimulation based on a posture state of a patient are described. For example, processing circuitry is configured to control delivery of a first informed stimulation pulse defined by at least a first value of an informed stimulation parameter, control delivery of a control stimulation pulse to a patient, the control stimulation pulse defined by at least a first value of a control stimulation parameter, determine a characteristic value of the ECAP signal elicited from the control stimulation pulse, receive, from a sensor, a posture state signal representing a posture state of the patient, and adjust, based on the characteristic value of the ECAP signal and the posture state signal, the first value of the informed stimulation parameter to a second value of the informed stimulation parameter.
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公开(公告)号：US11944819B2
公开(公告)日：2024-04-02
申请号：US16924990
申请日：2020-07-09
申请人： Medtronic, Inc.
发明人： Robert A. Corey , Kristin N. Hageman , David A. Dinsmoor , Hank Bink , Christopher L. Pulliam , Thomas Adamski
CPC分类号： A61N1/36139 , A61N1/025 , A61N1/0534 , A61N1/365 , A61N1/3956
摘要： Systems, devices, and techniques are described for analyzing evoked compound action potentials (ECAP) signals to assess the effect of a delivered electrical stimulation signal. In one example, a system includes a stimulation generator configured to deliver a stimulation pulse to a patient, sensing circuitry configured to sense an evoked compound action potential (ECAP) signal evoked from the stimulation pulse, and processing circuitry. The processing circuitry may be configured to determine a maximum value of a derivative of the ECAP signal, determine a minimum value of the derivative of the ECAP signal, determine, based on the maximum value of the derivative and the minimum value of the derivative, a characteristic value of the ECAP signal, and determine, based on the characteristic value of the ECAP signal, at least one parameter value at least partially defining electrical stimulation therapy to be delivered to the patient.
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公开(公告)号：US20220266028A1
公开(公告)日：2022-08-25
申请号：US17651705
申请日：2022-02-18
申请人： Medtronic, Inc.
IPC分类号： A61N1/36
摘要： An example method of cycling electric stimulation includes delivering, via an implantable device, electric stimulation to a patient in accordance with a first therapy program; monitoring, via the implantable device and while the electric stimulation is being delivered in accordance with the first therapy program, a biomarker; and responsive to determining the biomarker satisfies a threshold, delivering, via the implantable device, electric stimulation to the patient in accordance with a second therapy program that is different than the first therapy program.
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公开(公告)号：US20220096840A1
公开(公告)日：2022-03-31
申请号：US16948748
申请日：2020-09-30
申请人： Medtronic, Inc.
发明人： Jiashu Li , Duane L. Bourget , Kristin N. Hageman , Hank Bink
摘要： In one example, the disclosure describes a method comprising receiving, by processing circuitry, information indicative of one or more evoked compound action potential (ECAP) signals. The one or more ECAP signals are sensed by at least one electrode carried by a medical lead. The processing circuitry determining that at least one characteristic value of the one or more ECAP signals is outside of an expected range. Responsive to determining that the at least one characteristic value of the one or more ECAP signals is outside of the expected range, the processing circuitry performs a lead integrity test for the medical lead.
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