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公开(公告)号:US12053627B2
公开(公告)日:2024-08-06
申请号:US17199082
申请日:2021-03-11
Applicant: Medtronic, Inc.
Inventor: Scott R. Stanslaski , Timothy R. Abraham , Thomas Adamski , Timothy J. Denison , Robert S. Raike , Christopher L. Pulliam
CPC classification number: A61N1/0534 , A61B5/24 , A61B5/374 , A61B5/4836 , A61B5/4848 , A61B5/686 , A61B5/6868 , A61N1/36064 , A61N1/36067 , A61N1/36071 , A61N1/36082 , A61N1/36132 , A61N1/36135 , A61N1/36139 , A61N1/37247 , A61B5/0002 , A61N1/0476 , A61N1/36014 , A61N1/36096
Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first response of a first sensed signal of the patient to the electrical stimulation therapy and a second response of a second sensed signal of the patient to the electrical stimulation therapy. Based on the first response and the second response for controlling the electrical stimulation therapy, the medical system selects one of the first sensed signal and the second sensed signal of the patient. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.
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公开(公告)号:US11160983B2
公开(公告)日:2021-11-02
申请号:US16590661
申请日:2019-10-02
Applicant: MEDTRONIC, INC.
Inventor: Scott Stanslaski , Robert Devine , Timothy Denison , Vincent Roczniak , Todd Smith , Thomas Adamski
Abstract: Devices and methods provide for the sensing of physiological signals by providing a stimulation waveform that includes a stimulation pulse followed by an active recharge pulse to clear the charge in capacitors within the stimulation path. The active recharge pulse is followed by a period of passive recharge and then a period of no recharge. Non-neurological sources of artifacts within the sensed physiological signal may be handled by providing a brief period of passive recharge followed by a lengthy period of no recharge, which is made possible by the use of the active recharge pulse prior to the passive recharge. The period of no recharge removes any low impedance path to ground from the stimulation electrodes, which allows an amplifier of the sensing circuit to provide common mode rejection of non-neurological signals, such as cardiac signals, present at the sensing electrodes.
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公开(公告)号:US20210060331A1
公开(公告)日:2021-03-04
申请号:US17097776
申请日:2020-11-13
Applicant: Medtronic, Inc.
Inventor: Scott R. Stanslaski , Timothy R. Abraham , Thomas Adamski , Timothy J. Denison , Robert S. Raike
Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.
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公开(公告)号:US20180085585A1
公开(公告)日:2018-03-29
申请号:US15714867
申请日:2017-09-25
Applicant: Medtronic, Inc.
Inventor: Scott R. Stanslaski , Timothy R. Abraham , Thomas Adamski , Timothy J. Denison , Robert S. Raike
CPC classification number: A61N1/0534 , A61B5/0002 , A61B5/04001 , A61B5/4836 , A61B5/4848 , A61B5/686 , A61B5/6868 , A61N1/0476 , A61N1/36014 , A61N1/36064 , A61N1/36067 , A61N1/36071 , A61N1/36082 , A61N1/36096 , A61N1/36132 , A61N1/36135 , A61N1/36139 , A61N1/37247
Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.
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公开(公告)号:US11077305B2
公开(公告)日:2021-08-03
申请号:US15699873
申请日:2017-09-08
Applicant: MEDTRONIC, INC.
Inventor: Jonathon E. Giftakis , Timothy J. Denison , Paul H. Stypulkowski , Scott R. Stanslaski , Robert S. Raike , Mae Eng , David E. Linde , Thomas Adamski
Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.
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公开(公告)号:US10953222B2
公开(公告)日:2021-03-23
申请号:US15714888
申请日:2017-09-25
Applicant: Medtronic, Inc.
Inventor: Scott R. Stanslaski , Timothy R. Abraham , Thomas Adamski , Timothy J. Denison , Robert S. Raike , Christopher Pulliam
Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first response of a first sensed signal of the patient to the electrical stimulation therapy and a second response of a second sensed signal of the patient to the electrical stimulation therapy. Based on the first response and the second response for controlling the electrical stimulation therapy, the medical system selects one of the first sensed signal and the second sensed signal of the patient. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.
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公开(公告)号:US10471259B2
公开(公告)日:2019-11-12
申请号:US15444997
申请日:2017-02-28
Applicant: MEDTRONIC, INC.
Inventor: Scott Stanslaski , Robert Devine , Timothy Denison , Vincent Roczniak , Todd Smith , Thomas Adamski
Abstract: Devices and methods provide for the sensing of physiological signals by providing a stimulation waveform that includes a stimulation pulse followed by an active recharge pulse to clear the charge in capacitors within the stimulation path. The active recharge pulse is followed by a period of passive recharge and then a period of no recharge. Non-neurological sources of artifacts within the sensed physiological signal may be handled by providing a brief period of passive recharge followed by a lengthy period of no recharge, which is made possible by the use of the active recharge pulse prior to the passive recharge. The period of no recharge removes any low impedance path to ground from the stimulation electrodes, which allows an amplifier of the sensing circuit to provide common mode rejection of non-neurological signals, such as cardiac signals, present at the sensing electrodes.
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公开(公告)号:US20180085586A1
公开(公告)日:2018-03-29
申请号:US15714888
申请日:2017-09-25
Applicant: Medtronic, Inc.
Inventor: Scott R. Stanslaski , Timothy R. Abraham , Thomas Adamski , Timothy J. Denison , Robert S. Raike , Christopher Pulliam
CPC classification number: A61N1/0534 , A61B5/0002 , A61B5/04001 , A61B5/4836 , A61B5/4848 , A61B5/686 , A61B5/6868 , A61N1/0476 , A61N1/36014 , A61N1/36064 , A61N1/36067 , A61N1/36071 , A61N1/36082 , A61N1/36096 , A61N1/36132 , A61N1/36135 , A61N1/36139 , A61N1/37247
Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first response of a first sensed signal of the patient to the electrical stimulation therapy and a second response of a second sensed signal of the patient to the electrical stimulation therapy. Based on the first response and the second response for controlling the electrical stimulation therapy, the medical system selects one of the first sensed signal and the second sensed signal of the patient. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.
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公开(公告)号:US20230310841A1
公开(公告)日:2023-10-05
申请号:US18329367
申请日:2023-06-05
Applicant: Medtronic, Inc.
Inventor: Scott R. Stanslaski , Thomas Adamski , Duane L. Bourget , Timothy J. Denison , Benjamin P. Isaacson , Eric J. Panken , Jeffrey Herron
CPC classification number: A61N1/0534 , A61N1/36082 , A61B5/686 , A61N1/36132 , A61N1/36135 , A61B5/4848 , A61B5/4836 , A61B5/24 , A61B5/6868 , A61N1/36067 , A61N1/36064 , A61N1/36071 , A61N1/36139 , A61N1/37247 , A61B5/0002 , A61N1/0476
Abstract: Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.
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公开(公告)号:US20210322770A1
公开(公告)日:2021-10-21
申请号:US17364609
申请日:2021-06-30
Applicant: MEDTRONIC, INC.
Inventor: Jonathon E. Giftakis , Timothy J. Denison , Paul H. Stypulkowski , Scott R. Stanslaski , Robert S. Raike , Mae Eng , David E. Linde , Thomas Adamski
IPC: A61N1/36
Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.
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