公开(公告)号：US10004418B2

公开(公告)日：2018-06-26

申请号：US14604411

申请日：2015-01-23

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Paul J DeGroot

IPC: A61B5/0456 ,  A61N1/37 ,  A61B5/0452 ,  A61B5/00 ,  A61B5/046 ,  A61N1/368

CPC classification number: A61B5/0456 ,  A61B5/04525 ,  A61B5/046 ,  A61B5/4836 ,  A61B5/686 ,  A61N1/368 ,  A61N1/3702

Abstract: A method and medical device for identifying a cardiac waveform that includes sensing cardiac signals, determining a plurality of RR-intervals in response to the sensed cardiac signals, determining R-waves associated with the plurality of RR-intervals, determining P-waves in response to the determined R-waves, determining parameters associated with each P-wave, determining relative changes of the P-waves in response to the determined parameters, determining whether each of the P-waves match within a match threshold in response to the determined relative changes, and generating a P-wave template in response to each of the P-waves matching within the match threshold.

公开(公告)号：US10350417B2

公开(公告)日：2019-07-16

申请号：US14950952

申请日：2015-11-24

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Paul J DeGroot ,  Todd J Sheldon

IPC: A61N1/37 ,  A61N1/365 ,  A61N1/372 ,  A61N1/375 ,  A61B5/0452 ,  A61B5/0456 ,  A61B5/00

Abstract: An implantable medical device system includes an extracardiac sensing device and an intracardiac pacemaker. The sensing device senses a P-wave attendant to an atrial depolarization of the heart via housing-based electrodes carried by the sensing device when the sensing device is implanted outside the cardiovascular system and sends a trigger signal to the intracardiac pacemaker in response to sensing the P-wave. The intracardiac pacemaker detects the trigger signal and schedules a ventricular pacing pulse in response to the detected trigger signal.

公开(公告)号：US09095718B2

公开(公告)日：2015-08-04

申请号：US13856152

申请日：2013-04-03

Applicant: Medtronic, Inc.

Inventor： Xusheng Zhang ,  Paul J DeGroot ,  Jeffrey M Gillberg ,  Thomas J Mullen ,  Aleksandre T Sambelashvili

IPC: A61N1/36 ,  A61N1/365 ,  A61N1/362 ,  A61N1/368

CPC classification number: A61N1/36585 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

Abstract: A medical device and associated method for controlling a cardiac pacing therapy sense a first cardiac signal including events corresponding to cardiac electrical events and a second cardiac signal including events corresponding to cardiac hemodynamic events. A processor is enabled to measure a cardiac conduction time interval using the first cardiac signal and control a signal generator to deliver a pacing therapy. A pacing control parameter is adjusted to a plurality of settings during the pacing therapy delivery. A hemodynamic parameter value is measured from the second cardiac signal during application of each of the control parameter settings. The processor identifies an optimal setting from the plurality of settings and solves for a patient-specific equation defining the pacing control parameter as a function of the cardiac conduction time interval.

Abstract translation: 用于控制心脏起搏治疗的医疗装置和相关联的方法感测包括对应于心脏电气事件的事件的第一心脏信号和包括对应于心脏血流动力学事件的事件的第二心脏信号。 处理器能够使用第一心脏信号测量心脏传导时间间隔，并控制信号发生器以递送起搏治疗。 在起搏治疗递送期间，起搏控制参数被调整为多个设置。 在应用每个控制参数设置期间，从第二心脏信号测量血液动力学参数值。 处理器从多个设置中识别最佳设置，并且针对定义作为心脏传导时间间隔的函数的起搏控制参数的患者特定方程进行求解。

公开(公告)号：US10213125B2

公开(公告)日：2019-02-26

申请号：US14604468

申请日：2015-01-23

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Paul J DeGroot

IPC: A61B5/0456 ,  A61B5/046 ,  A61B5/00 ,  A61B5/0452

Abstract: A method and medical device for detecting a cardiac event that includes sensing a cardiac signal, determining RR-intervals in response to the sensed cardiac signal, detecting a cardiac event in response to the RR-intervals, iteratively sensing a predetermined number of P-waves in response to detecting the cardiac event, and confirming the cardiac event in response to the iteratively sensed P-waves.

公开(公告)号：US09717437B2

公开(公告)日：2017-08-01

申请号：US14520798

申请日：2014-10-22

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Paul J DeGroot

IPC: A61B5/046 ,  A61B5/0456 ,  A61B5/00 ,  A61N1/39

CPC classification number: A61B5/046 ,  A61B5/0456 ,  A61B5/686 ,  A61N1/3962

Abstract: A method and medical device for determining a cardiac event that includes sensing a cardiac signal, determining a predetermined number of sensed cardiac events in response to the sensed cardiac signal, determining a plurality of sensed event windows in response to the predetermined number of the sensed cardiac events, determining, for each of the plurality of sensed event windows, whether a number of paced events is less than a paced event threshold, determining whether intervals within the sensed event windows having a number of paced events less than the paced event threshold are greater than an interval threshold, determining an interval difference factor for each of the plurality of windows having intervals less than the interval threshold, and determining the cardiac event in response to the interval difference factors determined for each of the plurality of windows.