公开(公告)号：US20140114402A1

公开(公告)日：2014-04-24

申请号：US13659668

申请日：2012-10-24

Applicant: MEDTRONIC, INC.

Inventor： Sarah Ahlberg ,  Cynthia Clague ,  Brian McHenry ,  Susan Peterson ,  Scott Mosher ,  Karan Punga ,  Jason Quill

IPC: A61F2/24

CPC classification number: A61M25/0082 ,  A61B17/12036 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/12054 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2210/0085 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2230/0091 ,  A61F2250/006 ,  A61F2250/0069 ,  A61M31/005 ,  A61M2025/0087 ,  A61M2025/1052

Abstract: Devices and methods for delivering a sealing element post-implantation of valve prosthesis that functions to occlude or fill gaps present between the valve prosthesis and the native valve tissue, thereby reducing, minimizing, or eliminating leaks there through. In a first method, an injectable material is placed within a native valve sinus to form a sealing element that presses native valve leaflets against an outer surface of a heart valve prosthesis. In a second method, an injectable sealing material or a preformed annular sealing component is positioned between the outer surface or perimeter of a heart valve prosthesis and native heart valve tissue. In a third method, a preformed sealing element or component is placed within a heart valve prosthesis to press the prosthesis against native valve tissue.

Abstract translation: 用于递送瓣膜假体植入后的密封元件的装置和方法，其用于闭塞或填充阀门假体和天然瓣膜组织之间存在的间隙，从而减少，最小化或消除其中的泄漏。 在第一种方法中，将可注射材料放置在天然瓣膜内以形成密封元件，该密封元件将天然瓣膜压片压靠在心脏瓣膜假体的外表面上。 在第二种方法中，可注射密封材料或预成型的环形密封部件位于心脏瓣膜假体和天然心脏瓣膜组织的外表面或周边之间。 在第三种方法中，将预先形成的密封元件或部件放置在心脏瓣膜假体内以将假体按压于自然瓣膜组织。

公开(公告)号：US20220304805A1

公开(公告)日：2022-09-29

申请号：US17841965

申请日：2022-06-16

Applicant: Medtronic, Inc.

Inventor： Cynthia Clague ,  Scott Mosher ,  Marian Creaven ,  Declan Costello ,  Gavin Kenny ,  Michael Krivoruchko ,  Adam Shipley ,  Mark Torianni ,  Kshitija Garde ,  Eric Richardson

IPC: A61F2/24

Abstract: A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis.

公开(公告)号：US09144663B2

公开(公告)日：2015-09-29

申请号：US13659668

申请日：2012-10-24

Applicant: Medtronic, Inc.

Inventor： Sarah Ahlberg ,  Cynthia Clague ,  Susan Peterson ,  Scott Mosher ,  Karan Punga

IPC: A61F2/24 ,  A61M25/00 ,  A61B17/12 ,  A61M31/00 ,  A61M25/10

CPC classification number: A61M25/0082 ,  A61B17/12036 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/12054 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2210/0085 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2230/0091 ,  A61F2250/006 ,  A61F2250/0069 ,  A61M31/005 ,  A61M2025/0087 ,  A61M2025/1052

Abstract: Devices and methods for delivering a sealing element post-implantation of valve prosthesis that functions to occlude or fill gaps present between the valve prosthesis and the native valve tissue, thereby reducing, minimizing, or eliminating leaks there through. In a first method, an injectable material is placed within a native valve sinus to form a sealing element that presses native valve leaflets against an outer surface of a heart valve prosthesis. In a second method, an injectable sealing material or a preformed annular sealing component is positioned between the outer surface or perimeter of a heart valve prosthesis and native heart valve tissue. In a third method, a preformed sealing element or component is placed within a heart valve prosthesis to press the prosthesis against native valve tissue.

Abstract translation: 用于递送瓣膜假体植入后的密封元件的装置和方法，其用于闭塞或填充阀门假体和天然瓣膜组织之间存在的间隙，从而减少，最小化或消除其中的泄漏。 在第一种方法中，将可注射材料放置在天然瓣膜内以形成密封元件，该密封元件将天然瓣膜小叶压靠在心脏瓣膜假体的外表面上。 在第二种方法中，可注射密封材料或预成型的环形密封部件位于心脏瓣膜假体和天然心脏瓣膜组织的外表面或周边之间。 在第三种方法中，将预先形成的密封元件或部件放置在心脏瓣膜假体内以将假体按压于自然瓣膜组织。

公开(公告)号：US20140236287A1

公开(公告)日：2014-08-21

申请号：US13772676

申请日：2013-02-21

Applicant: MEDTRONIC, INC.

Inventor： Cynthia Clague ,  Scott Mosher ,  Marian Creaven ,  Declan Costello ,  Gavin Kenny ,  Michael Krivoruchko ,  Adam Shipley ,  Mark Torrianni ,  Kshitija Garde ,  Eric Richardson

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0069 ,  A61F2310/00023

Abstract: A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis.

Abstract translation: 防止瓣膜间泄漏的方法包括同时传送心脏瓣膜假体和环形密封部件。 在输送期间，密封部件从心脏瓣膜假体的第一位置移动到与心脏瓣膜假体的第一位置纵向间隔开的第二位置。 密封部件通过心脏瓣膜假体的轮廓外表面在第二位置处固定在心脏瓣膜假体周围。 密封部件可以是柔性环，或者可以是具有在圆柱形套筒上纵向延伸的多个肋的圆柱形柔性套管。 肋条用于展开密封部件，使得圆柱形套筒的至少一部分向外离开远离心脏瓣膜假体的外表面。