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    MEDICAL DEVICE SYSTEM AND METHOD FOR DETERMINING HIS BUNDLE PACING CAPTURE
    1.
    发明申请
    MEDICAL DEVICE SYSTEM AND METHOD FOR DETERMINING HIS BUNDLE PACING CAPTURE 审中-公开

    公开(公告)号：US20200261731A1

    公开(公告)日：2020-08-20

    申请号：US16791661

    申请日：2020-02-14

    Applicant: Medtronic, Inc.

    Inventor： Subham GHOSH

    IPC: A61N1/37 ,  A61N1/372 ,  A61N1/365 ,  A61N1/39

    Abstract: In a medical device system, a computer apparatus is configured to receive body surface electrical signals from an electrode apparatus including multiple external electrodes. The computing apparatus generates electrical dyssynchrony data from the body surface electrical signals during delivery of His bundle pacing pulses and identifies effective His bundle capture based on the electrical dyssynchrony data. The computing apparatus generates an indication of His bundle capture in response to identifying the effective His bundle capture.

    METHOD AND DETERMINATION OF CARDIAC ACTIVATION FROM ELECTROGRAMS WITH MULTIPLE DEFLECTIONS
    6.
    发明申请
    METHOD AND DETERMINATION OF CARDIAC ACTIVATION FROM ELECTROGRAMS WITH MULTIPLE DEFLECTIONS 有权
    从多种偏倚的电子学中心脏激活的方法和确定

    公开(公告)号：US20150126841A1

    公开(公告)日：2015-05-07

    申请号：US14597472

    申请日：2015-01-15

    Applicant: Medtronic, Inc.

    Inventor： Subham GHOSH

    IPC: A61B5/046 ,  A61B5/042 ,  A61B5/044

    CPC classification number: A61B5/046 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/0432 ,  A61B5/044 ,  A61B5/0456 ,  A61B5/7239

    Abstract: A method and system for determining activation times for electric potentials from complex electrograms to identify the location of arrhythmic sources or drivers. The method includes counting a number deflections in a recorded cardiac electrogram signal from at least one electrode for a predetermined amount of time. A deflection time is identified for each of the counted number of deflections. A most negative slope is identified between each of the identified deflections times. Each of the identified most negative slopes is correlated to a possible activation time. Each possible activation time is associated with a corresponding electrode from the at least one electrode. A spatial voltage gradient at each corresponding electrode is calculated for each possible activation time. The greatest spatial voltage gradient is identified. The greatest spatial voltage gradient is correlated to an activation time.

    Abstract translation: 一种用于从复杂电描记图确定电位的激活时间以识别心律失常源或驱动器的位置的方法和系统。 该方法包括在来自至少一个电极的记录的心电图信号中对预定时间量的数量偏转进行计数。 为每个计数的偏转数确定偏转时间。 每个确定的偏差次数之间确定最负的斜率。 每个确定的最负斜率与可能的激活时间相关。 每个可能的激活时间与来自至少一个电极的相应电极相关联。 对于每个可能的激活时间，计算每个相应电极处的空间电压梯度。 确定最大的空间电压梯度。 最大的空间电压梯度与激活时间相关。

    MEDICAL DEVICE SYSTEM AND METHOD FOR DETERMINING HIS BUNDLE PACING CAPTURE
    7.
    发明申请
    MEDICAL DEVICE SYSTEM AND METHOD FOR DETERMINING HIS BUNDLE PACING CAPTURE 有权

    公开(公告)号：US20220193421A1

    公开(公告)日：2022-06-23

    申请号：US17692740

    申请日：2022-03-11

    Applicant: Medtronic, Inc.

    Inventor： Subham GHOSH

    IPC: A61N1/37 ,  A61N1/39 ,  A61N1/365 ,  A61N1/372

    Abstract: In a medical device system, a computer apparatus is configured to receive body surface electrical signals from an electrode apparatus including multiple external electrodes. The computing apparatus generates electrical dyssynchrony data from the body surface electrical signals during delivery of His bundle pacing pulses and identifies effective His bundle capture based on the electrical dyssynchrony data. The computing apparatus generates an indication of His bundle capture in response to identifying the effective His bundle capture.

    EFFICIENT DELIVERY OF MULTI-SITE PACING
    8.
    发明申请
    EFFICIENT DELIVERY OF MULTI-SITE PACING 审中-公开

    公开(公告)号：US20190160288A1

    公开(公告)日：2019-05-30

    申请号：US16196732

    申请日：2018-11-20

    Applicant: Medtronic, Inc.

    Inventor： Berthold STEGEMANN ,  Richard CORNELUSSEN ,  Joeri HEYNENS ,  Subham GHOSH

    IPC: A61N1/368 ,  A61N1/362 ,  A61N1/365 ,  A61B5/0468 ,  A61N1/05 ,  A61B5/0464 ,  A61N1/39

    Abstract: An implantable device and associated method for delivering multi-site pacing therapy is disclosed. The device comprises a set of electrodes including a first and second left ventricular electrodes spatially separated from one another and a right ventricular electrode, all coupled to an implantable pulse generator. The processing circuit coupled to the implantable pulse generator, the processing circuit configured to determine whether a prospective heart failure condition has occurred and if so to trigger the pulse generator to switch from a first pacing mode to a second pacing mode, the first pacing mode comprising delivering only a first pacing pulse to a left ventricle (LV) and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle and the second pacing mode comprising delivering first and a second pacing pulses to the LV and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle.

    METHOD AND DETERMINATION OF CARDIAC ACTIVATION FROM ELECTROGRAMS WITH MULTIPLE DEFLECTIONS
    9.
    发明申请
    METHOD AND DETERMINATION OF CARDIAC ACTIVATION FROM ELECTROGRAMS WITH MULTIPLE DEFLECTIONS 有权
    从多种偏倚的电子学中心脏激活的方法和确定

    公开(公告)号：US20140235987A1

    公开(公告)日：2014-08-21

    申请号：US13773030

    申请日：2013-02-21

    Applicant: MEDTRONIC, INC.

    Inventor： Subham GHOSH

    IPC: A61B5/046 ,  A61B5/042 ,  A61B5/04 ,  A61B5/0432 ,  A61B5/044

    CPC classification number: A61B5/046 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/0432 ,  A61B5/044 ,  A61B5/0456 ,  A61B5/7239

    Abstract: A method and system for determining activation times for electric potentials from complex electrograms to identify the location of arrhythmic sources or drivers. The method includes counting a number deflections in a recorded cardiac electrogram signal from at least one electrode for a predetermined amount of time. A deflection time is identified for each of the counted number of deflections. A most negative slope is identified between each of the identified deflections times. Each of the identified most negative slopes is correlated to a possible activation time. Each possible activation time is associated with a corresponding electrode from the at least one electrode. A spatial voltage gradient at each corresponding electrode is calculated for each possible activation time. The greatest spatial voltage gradient is identified. The greatest spatial voltage gradient is correlated to an activation time.

    Abstract translation: 一种用于从复杂电描记图确定电位的激活时间以识别心律失常源或驱动器的位置的方法和系统。 该方法包括在来自至少一个电极的记录的心电图信号中对预定时间量的数量偏转进行计数。 为每个计数的偏转数确定偏转时间。 每个确定的偏差次数之间确定最负的斜率。 每个确定的最负斜率与可能的激活时间相关。 每个可能的激活时间与来自至少一个电极的相应电极相关联。 对于每个可能的激活时间，计算每个相应电极处的空间电压梯度。 确定最大的空间电压梯度。 最大的空间电压梯度与激活时间相关。

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