公开(公告)号：US11253176B2

公开(公告)日：2022-02-22

申请号：US16426750

申请日：2019-05-30

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Yunfeng Lu ,  Jay Mung

IPC: A61B5/145 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/00

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

公开(公告)号：US20170181677A1

公开(公告)日：2017-06-29

申请号：US14980260

申请日：2015-12-28

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Yunfeng Lu ,  Jay Mung

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/053 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7278

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

公开(公告)号：US20220125352A1

公开(公告)日：2022-04-28

申请号：US17571812

申请日：2022-01-10

Applicant: Medtronic MiniMed, Inc.

Inventor： Andrea Varsavsky ,  Yunfeng Lu ,  Jay Mung

IPC: A61B5/145 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/00

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

公开(公告)号：US10349872B2

公开(公告)日：2019-07-16

申请号：US14980260

申请日：2015-12-28

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Yunfeng Lu ,  Jay Mung

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/053

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

公开(公告)号：US20190274604A1

公开(公告)日：2019-09-12

申请号：US16426750

申请日：2019-05-30

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Yunfeng Lu ,  Jay Mung

IPC: A61B5/145 ,  A61B5/053 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/1486

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

公开(公告)号：US20170181671A1

公开(公告)日：2017-06-29

申请号：US14980114

申请日：2015-12-28

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Jay Mung ,  Yunfeng Lu ,  Mohammad Mehdi Korjani

IPC: A61B5/1495 ,  A61B5/053 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1473

CPC classification number: A61B5/1495 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/7203 ,  A61B5/7225

Abstract: An unscented Kalman filter is used to enable sensor calibration independently of the actual design of the subject sensors. By utilizing an unscented Kalman filter, an underlying calibration methodology is developed that is sensor-unspecific, such that a single calibration methodology and related systems may be used to calibrate various sensors, without the need to re-calculate a calibration factor for each specific sensor, and without the need to design a separate filtering mechanism to compensate for noise. In this way, various calibration inputs can be allowed to change over time without the need to change the codebase on which the calibration methodology otherwise operates. In multi-electrode systems, the methodology may incorporate a fusion algorithm to provide a single, fused sensor glucose value. The fusion algorithm may incorporate, and/or work in conjunction with, Electrochemical Impedance Spectroscopy (EIS) procedures.