公开(公告)号：US20240138981A1

公开(公告)日：2024-05-02

申请号：US18410981

申请日：2024-01-11

申请人： Medtronic Vascular, Inc.

发明人： Jill Mendelson ,  Michele Silver ,  Michael Gloss ,  Timothy Groen ,  Paul Rothstein ,  Jeffrey Sandstrom ,  Phil Haarstad ,  Joel Racchini ,  David Blaeser

IPC分类号： A61F2/24 ,  A61F2/95

CPC分类号： A61F2/2427 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/95 ,  A61F2/07 ,  A61F2/9517

摘要： Delivery devices for delivering a self-expanding prosthetic heart valve are disclosed. The delivery device includes at least one cord is configured to selectively cinch the self-expanding prosthetic heart valve. The delivery device further includes at least one self-expanding release pin comprising a proximal segment, a distal segment, and an intermediate segment positioned between the proximal segment and the distal segment. The at least one self-expanding release pin includes a normal, expanded condition wherein the intermediate segment extends radially outward relative to a central axis of the spindle from the proximal segment to the distal segment. The delivery device further includes a capsule configured to be distally extended relative to the spindle to collapse the at least one self-expanding release pin from the normal, expanded condition of the at least one self-expanding release pin to a collapsed condition of the at least one self-expanding release pin.

公开(公告)号：US11406496B2

公开(公告)日：2022-08-09

申请号：US16916274

申请日：2020-06-30

申请人： Medtronic Vascular, Inc.

发明人： Elliot Howard ,  Amy Hallak ,  Ana Menk ,  Matthew Weston ,  Joel Racchini

IPC分类号： A61F2/24

摘要： Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.

公开(公告)号：US10888420B2

公开(公告)日：2021-01-12

申请号：US15458387

申请日：2017-03-14

申请人： Medtronic Vascular, Inc.

发明人： Michael Bateman ,  Cynthia Clague ,  Jeffrey Sandstrom ,  Joel Racchini ,  James R. Keogh

IPC分类号： A61F2/24 ,  A61F2/844 ,  A61F2/852

摘要： Stented prosthetic heart valves comprising a stent frame having a compressed arrangement for delivery within a patient's vasculature and an expanded arrangement for deployment within a native heart valve. The stented prosthetic heart valves including a paravalvular leakage prevention or mitigation wrap that encircles a stent frame and is formed of a flexible material having a variable diameter defined by a greatest distance between the wrap and the stent frame. The wrap further includes a first end coupled to the stent frame and an opposing second end that is not coupled to the stent frame, wherein the wrap can selectively enlarge its diameter in situ via movement of the second end. Devices for and methods of selectively deploying the wrap are also disclosed.

公开(公告)号：US10729542B2

公开(公告)日：2020-08-04

申请号：US15792991

申请日：2017-10-25

申请人： Medtronic Vascular, Inc.

发明人： Elliot Howard ,  Amy Hallak ,  Ana Menk ,  Matthew Weston ,  Joel Racchini

IPC分类号： A61F2/24

摘要： Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.

公开(公告)号：US20170258587A1

公开(公告)日：2017-09-14

申请号：US15069102

申请日：2016-03-14

申请人： Medtronic Vascular, Inc.

发明人： Michael Gloss ,  Timothy Groen ,  Paul Rothstein ,  Jeffrey Sandstrom ,  Phil Haarstad ,  Joel Racchini ,  Tuan Doan

IPC分类号： A61F2/24

摘要： Disclosed embodiments and methods provide solutions for coupling and decoupling of a delivery device from a stented prosthetic heart valve with one or more release mechanisms. In situations when one or more sutures get tangled or caught upon attempted retraction of the delivery device and sutures after deployment of the stented prosthetic heart valve, a secondary release mechanism can be provided to sever the suture(s) or release the suture(s) from the delivery device. Exemplary secondary release mechanisms include high resistance inserts, cutters and balloon expandable devices. Methods of releasing the sutures from the delivery device or severing the suture(s) are also disclosed.

公开(公告)号：US20160213470A1

公开(公告)日：2016-07-28

申请号：US15000378

申请日：2016-01-19

申请人： Medtronic Vascular, Inc.

发明人： Sarah Ahlberg ,  Marc Anderson ,  Donna Barrett ,  Evelyn Birmingham ,  Constantin Ciobanu ,  Kieran Cunningham ,  Paul Devereux ,  Niall Duffy ,  John Gallagher ,  Patrick Griffin ,  Frank Harewood ,  Gerry McCaffrey ,  Deirdre McGowan Smyth ,  Bernard Mulvihill ,  Herinaina Rabarimanantsoa Jamous ,  Joel Racchini ,  Jeffrey Sandstrom ,  Frank White

IPC分类号： A61F2/24

摘要： Embodiments hereof relate to a delivery system for a transcatheter valve prosthesis, the delivery system having an integral centering mechanism to circumferentially center both the delivery system and the valve prosthesis within a vessel at the target implantation site. The centering mechanism may include expandable wings that may be selectively aligned with openings formed through a sidewall of an outer shaft of the delivery system, a coiled wing that may be selectively exposed through an opening formed through a sidewall of an outer shaft of the delivery system, a plurality of elongated filaments extending through a plurality of lumens of an outermost shaft of the delivery system that may be selectively deployed or expanded, an outer shaft that includes at least one pre-formed deflection segment formed thereon, a tool having a deployable lever arm, and/or a plurality of loops deployable via simultaneous longitudinal and rotational movement.

摘要翻译： 本发明的实施例涉及一种用于经导管瓣膜假体的输送系统，所述输送系统具有整体定心机构，以在目标植入部位的血管内周向中心输送系统和瓣膜假体。 定心机构可以包括可膨胀的翼，其可选择性地与通过输送系统的外轴的侧壁形成的开口对准，螺旋翼可以通过穿过输送系统的外轴的侧壁形成的开口而被选择性地暴露 ，延伸穿过可以选择性地展开或展开的输送系统的最外轴的多个内腔的多个细长丝，包括形成在其上的至少一个预成形偏转段的外轴，具有可展开杆 臂和/或可通过同时纵向和旋转运动展开的多个环。

公开(公告)号：US11957575B2

公开(公告)日：2024-04-16

申请号：US17863588

申请日：2022-07-13

申请人： Medtronic Vascular, Inc.

发明人： Elliot Howard ,  Amy Hallak ,  Ana Menk ,  Matthew Weston ,  Joel Racchini

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/243 ,  A61F2/2409 ,  A61F2220/0075 ,  A61F2250/0069

摘要： Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.

公开(公告)号：US10765513B2

公开(公告)日：2020-09-08

申请号：US15614890

申请日：2017-06-06

申请人： Medtronic Vascular, Inc.

发明人： Jill Mendelson ,  Michele Silver ,  Michael Gloss ,  Timothy Groen ,  Paul Rothstein ,  Jeffrey Sandstrom ,  Phil Haarstad ,  Joel Racchini ,  David Blaeser

IPC分类号： A61F2/24 ,  A61F2/95 ,  A61F2/07 ,  A61F2/962

摘要： Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature. The cord is tensioned to crimp the prosthesis to a compressed condition for delivery to a target site. Tension is lessened to allow the prosthesis to self-expand. In a tethered and expanded state in which the prosthesis has self-expanded and is connected to the spindle by the cord, the lateral control feature directs the spindle to a prescribed location relative to the prosthesis appropriate for a functional evaluation of the prosthesis. In some embodiments, the spindle is directed to a center of the prosthesis; in other embodiments, the spindle is held at a commissure of the prosthesis. The lateral control features of the present disclosure assume numerous forms.

公开(公告)号：US12036114B2

公开(公告)日：2024-07-16

申请号：US17116431

申请日：2020-12-09

申请人： Medtronic Vascular, Inc.

发明人： Michael Bateman ,  Cynthia Clague ,  Jeffrey Sandstrom ,  Joel Racchini ,  James R. Keogh

IPC分类号： A61F2/24 ,  A61F2/844 ,  A61F2/852

CPC分类号： A61F2/2418 ,  A61F2/2409 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/844 ,  A61F2/852 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2250/0069

摘要： Stented prosthetic heart valves comprising a stent frame having a compressed arrangement for delivery within a patient's vasculature and an expanded arrangement for deployment within a native heart valve. The stented prosthetic heart valves including a paravalvular leakage prevention or mitigation wrap that encircles a stent frame and is formed of a flexible material having a variable diameter defined by a greatest distance between the wrap and the stent frame. The wrap further includes a first end coupled to the stent frame and an opposing second end that is not coupled to the stent frame, wherein the wrap can selectively enlarge its diameter in situ via movement of the second end. Devices for and methods of selectively deploying the wrap are also disclosed.

公开(公告)号：US11903828B2

公开(公告)日：2024-02-20

申请号：US16934119

申请日：2020-07-21

申请人： Medtronic Vascular, Inc.

发明人： Jill Mendelson ,  Michele Silver ,  Michael Gloss ,  Timothy Groen ,  Paul Rothstein ,  Jeffrey Sandstrom ,  Phil Haarstad ,  Joel Racchini ,  David Blaeser

IPC分类号： A61F2/24 ,  A61F2/95 ,  A61F2/07 ,  A61F2/962

CPC分类号： A61F2/2427 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/95 ,  A61F2/07 ,  A61F2/243 ,  A61F2/2418 ,  A61F2/9517 ,  A61F2/962 ,  A61F2230/0063

摘要： Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature. The cord is tensioned to crimp the prosthesis to a compressed condition for delivery to a target site. Tension is lessened to allow the prosthesis to self-expand. In a tethered and expanded state in which the prosthesis has self-expanded and is connected to the spindle by the cord, the lateral control feature directs the spindle to a prescribed location relative to the prosthesis appropriate for a functional evaluation of the prosthesis. In some embodiments, the spindle is directed to a center of the prosthesis; in other embodiments, the spindle is held at a commissure of the prosthesis. The lateral control features of the present disclosure assume numerous forms.