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公开(公告)号:US10456243B2
公开(公告)日:2019-10-29
申请号:US14879861
申请日:2015-10-09
发明人: Scott Robertson , Elliot Howard
摘要: Prosthetic heart valve devices and associated methods for percutaneous heart valve replacement are disclosed herein. A transcatheter valve prosthesis configured in accordance herewith includes a frame having a valve support and one or more support arms coupled thereto. The one or more support arms are configured to extend from the second end of the valve support toward the first end when the valve prosthesis is in an expanded configuration. When deployed in the expanded configuration, the one or more support arms have a curvilinear shape, such as a substantially S-shape, that at least partially engages tissue at the native heart valve.
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公开(公告)号:US20220338984A1
公开(公告)日:2022-10-27
申请号:US17863588
申请日:2022-07-13
发明人: Elliot Howard , Amy Hallak , Ana Menk , Matthew Weston , Joel Racchini
IPC分类号: A61F2/24
摘要: Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.
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公开(公告)号:US20200330223A1
公开(公告)日:2020-10-22
申请号:US16916274
申请日:2020-06-30
发明人: Elliot Howard , Amy Hallak , Ana Menk , Matthew Weston , Joel Racchini
IPC分类号: A61F2/24
摘要: Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.
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公开(公告)号:US20180110617A1
公开(公告)日:2018-04-26
申请号:US15792991
申请日:2017-10-25
发明人: Elliot Howard , Amy Hallak , Ana Menk , Matthew Weston , Joel Racchini
IPC分类号: A61F2/24
摘要: Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.
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公开(公告)号:US11406496B2
公开(公告)日:2022-08-09
申请号:US16916274
申请日:2020-06-30
发明人: Elliot Howard , Amy Hallak , Ana Menk , Matthew Weston , Joel Racchini
IPC分类号: A61F2/24
摘要: Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.
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公开(公告)号:US10729542B2
公开(公告)日:2020-08-04
申请号:US15792991
申请日:2017-10-25
发明人: Elliot Howard , Amy Hallak , Ana Menk , Matthew Weston , Joel Racchini
IPC分类号: A61F2/24
摘要: Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.
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公开(公告)号:US20170100236A1
公开(公告)日:2017-04-13
申请号:US14879861
申请日:2015-10-09
发明人: Scott Robertson , Elliot Howard
IPC分类号: A61F2/24
摘要: Prosthetic heart valve devices and associated methods for percutaneous heart valve replacement are disclosed herein. A transcatheter valve prosthesis configured in accordance herewith includes a frame having a valve support and one or more support arms coupled thereto. The one or more support arms are configured to extend from the second end of the valve support toward the first end when the valve prosthesis is in an expanded configuration. When deployed in the expanded configuration, the one or more support arms have a curvilinear shape, such as a substantially S-shape, that at least partially engages tissue at the native heart valve.
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公开(公告)号:US11957575B2
公开(公告)日:2024-04-16
申请号:US17863588
申请日:2022-07-13
发明人: Elliot Howard , Amy Hallak , Ana Menk , Matthew Weston , Joel Racchini
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2/2412 , A61F2/243 , A61F2/2409 , A61F2220/0075 , A61F2250/0069
摘要: Stented prosthetic heart valves including a stent frame having a plurality of stent frame support structures collectively defining an interior surface, an exterior surface and a plurality of cells. The stented prosthetic heart valve further including a valve structure including valve leaflets disposed within and secured to the stent frame and defining a margin of attachment. The stented prosthetic heart valve including one or both of an outer paravalvular leakage prevention wrap and an inner skirt for supporting the valve leaflets. In various embodiments, the outer wrap is positioned entirely on one side of the margin of attachment. In embodiments including an inner skirt, the outer wrap and the inner skirt are on opposite sides of the margin of attachment such that the inner skirt and the outer wrap do not overlap. In other embodiments, the outer wrap includes a plurality of zones having varying thickness.
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公开(公告)号:US10299916B2
公开(公告)日:2019-05-28
申请号:US15383077
申请日:2016-12-19
发明人: Tracey Tien , Carol Eberhardt , Kshitija Garde , Benjamin Wong , Wei Wang , Elliot Howard , Laura McKinley , Karl Olney , Taylor Winters
IPC分类号: A61F2/24 , A61L27/26 , A61L27/50 , C09J4/00 , C09J189/00 , A61L27/36 , A61L24/06 , A61L24/10
摘要: A method of reinforcing or repairing a bioprosthetic tissue for use as a prosthetic valve leaflet. The method includes evaluating a bioprosthetic tissue, identifying a defect in the bioprosthetic tissue, and selectively applying an adhesive to a surface of the bioprosthetic tissue at the defect prior to implantation in a patient.
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公开(公告)号:US20180243089A1
公开(公告)日:2018-08-30
申请号:US15964403
申请日:2018-04-27
发明人: Laura McKinley , Benjamin Wong , Wei Wang , Elliot Howard , Joshua Dudney , Tracey Tien , Karl Olney
IPC分类号: A61F2/24
摘要: Conditioned bioprosthetic tissues for forming prosthetic valves including a sheet of bioprosthetic tissue having a first major surface and a second major surface. The first major surface has a pattern including at least one depressed region and areas of relief adjacent to the at least one depressed region. The at least one depressed region has a first tissue density that is greater than a second tissue density of the areas of relief.
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