公开(公告)号：US07642097B2

公开(公告)日：2010-01-05

申请号：US12163751

申请日：2008-06-27

申请人： Mel N. Kronick ,  Barnett E. Saunders ,  Matthew J. Marton ,  John S. Hinchcliffe ,  Dianne Rees ,  Carol T. Schembri

发明人： Mel N. Kronick ,  Barnett E. Saunders ,  Matthew J. Marton ,  John S. Hinchcliffe ,  Dianne Rees ,  Carol T. Schembri

IPC分类号： B01L9/00

CPC分类号： B01L9/52 ,  B01J2219/00531 ,  B01J2219/00547 ,  B01J2219/00608 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00662 ,  B01L3/508 ,  B01L2300/0636 ,  B01L2300/0819 ,  B01L2300/0822 ,  G02B21/34 ,  Y10T436/25 ,  Y10T436/2575

摘要： Methods and devices are disclosed for microarray analysis. In one embodiment a method is disclosed for processing a non-standard size slide having an array of chemical compounds attached to a surface of the slide. A sample is exposed to the surface of the non-standard size slide wherein components in the sample bind to the chemical compounds on the surface of the slide. The sample and the slide are incubated under conditions for carrying out the binding reactions, and the surface of the non-standard size slide is examined for the results of the binding reactions. Prior to the exposing step or the incubating step or the examining step, the non-standard size slide is placed into a slide holder comprising a slide-holding section a slide-holding section adapted to dispose the non-standard size slide to a processing instrument in a manner similar to that for a standard size slide. The non-standard size slide may also include an identifier such as a bar code.

摘要翻译： 公开了用于微阵列分析的方法和装置。 在一个实施方案中，公开了一种用于处理具有附着到载玻片的表面的化学化合物阵列的非标尺寸载玻片的方法。 将样品暴露于非标准尺寸载玻片的表面，其中样品中的组分与载玻片表面上的化合物结合。 样品和载玻片在进行结合反应的条件下孵育，并检查非标准大小载玻片的表面结合反应的结果。 在暴露步骤或孵化步骤或检查步骤之前，将非标准尺寸的载玻片放置在载玻片保持器中，滑动保持器包括滑动保持部分，该滑动保持部分适于将非标准尺寸滑块配置到处理器械 以类似于标准尺寸幻灯片的方式。 非标准尺寸的幻灯片还可以包括诸如条形码的标识符。

公开(公告)号：US20080261826A1

公开(公告)日：2008-10-23

申请号：US12163751

申请日：2008-06-27

申请人： Mel N. Kronick ,  Barnett E. Saunders ,  Matthew J. Marton ,  John S. Hinchcliffe ,  Dianne Rees ,  Carol T. Schembri

发明人： Mel N. Kronick ,  Barnett E. Saunders ,  Matthew J. Marton ,  John S. Hinchcliffe ,  Dianne Rees ,  Carol T. Schembri

IPC分类号： C40B30/04 ,  C40B50/14 ,  C40B40/00

CPC分类号： B01L9/52 ,  B01J2219/00531 ,  B01J2219/00547 ,  B01J2219/00608 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00662 ,  B01L3/508 ,  B01L2300/0636 ,  B01L2300/0819 ,  B01L2300/0822 ,  G02B21/34 ,  Y10T436/25 ,  Y10T436/2575

摘要： Methods and devices are disclosed for microarray analysis. In one embodiment a method is disclosed for processing a non-standard size slide having an array of chemical compounds attached to a surface of the slide. A sample is exposed to the surface of the non-standard size slide wherein components in the sample bind to the chemical compounds on the surface of the slide. The sample and the slide are incubated under conditions for carrying out the binding reactions, and the surface of the non-standard size slide is examined for the results of the binding reactions. Prior to the exposing step or the incubating step or the examining step, the non-standard size slide is placed into a slide holder comprising a slide-holding section a slide-holding section adapted to dispose the non-standard size slide to a processing instrument in a manner similar to that for a standard size slide. The non-standard size slide may also include an identifier such as a bar code.

摘要翻译： 公开了用于微阵列分析的方法和装置。 在一个实施方案中，公开了一种用于处理具有附着到载玻片的表面的化学化合物阵列的非标尺寸载玻片的方法。 将样品暴露于非标准尺寸载玻片的表面，其中样品中的组分与载玻片表面上的化合物结合。 将样品和载玻片在进行结合反应的条件下孵育，并检查非标准尺寸载玻片的表面的结合反应结果。 在暴露步骤或孵化步骤或检查步骤之前，将非标准尺寸的载玻片放置在载玻片保持器中，滑动保持器包括滑动保持部分，该滑动保持部分适于将非标准尺寸滑块配置到处理器械 以类似于标准尺寸幻灯片的方式。 非标准尺寸的幻灯片还可以包括诸如条形码的标识符。

公开(公告)号：US5314407A

公开(公告)日：1994-05-24

申请号：US917923

申请日：1992-07-21

申请人： David C. Auth ,  Michael J. Intlekofer ,  Michael W. Slota ,  John S. Hinchcliffe ,  Thomas J. Clement

发明人： David C. Auth ,  Michael J. Intlekofer ,  Michael W. Slota ,  John S. Hinchcliffe ,  Thomas J. Clement

IPC分类号： A61B17/22

CPC分类号： A61B17/320758

摘要： The present invention is a clinically practical, rotational angioplasty system which employs a unique rotary ablative device for mechanically abrading, and thereby removing, lesions from within a patient's vessels. The device has a gas driven prime mover connected, via a hollow helical drive assembly, to an ellipsoidal, rotating, ablative burr which is used for the actual recanalization of the patient's vessel. The burr is provided with a central opening therethrough, which, together with the hollow drive assembly, permits the burr and drive assembly to be threaded over a guide wire similar to the type conventionally used in a catheterization procedure. The drive assembly is located within a hollow sheath which prevents the rotating drive assembly from contacting the inner walls of a patient's vessel.

摘要翻译： 本发明是一种临床实用的旋转血管成形术系统，其采用独特的旋转烧蚀装置，用于机械研磨，从而从病人血管内去除病变。 该装置具有通过中空螺旋驱动组件连接到用于患者血管的实际再通的椭圆形，旋转，烧蚀性毛刺的气体驱动原动机。 毛刺具有穿过其的中心开口，该中心开口与中空驱动组件一起允许毛刺和驱动组件穿过类似于在导管插入程序中常规使用的类型的导丝。 驱动组件位于中空护套内，防止旋转驱动组件接触患者血管的内壁。