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公开(公告)号:US20100330082A1
公开(公告)日:2010-12-30
申请号:US12680243
申请日:2008-10-01
IPC分类号: A61K39/395 , C12N5/00 , A61K31/713 , C12Q1/02 , A61P35/00 , A61K31/517
CPC分类号: C07K16/18 , A61K39/395 , A61K2039/505 , C07K16/30 , C07K2317/76 , C07K2317/77 , C12N15/113 , C12N2310/14 , A61K2300/00
摘要: NLRR-1 antagonists and methods of their use in treating cancer and other disorders are provided.
摘要翻译: 提供NLRR-1拮抗剂及其用于治疗癌症和其它疾病的方法。
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公开(公告)号:US08691222B2
公开(公告)日:2014-04-08
申请号:US12680243
申请日:2008-10-01
IPC分类号: A61K39/395
CPC分类号: C07K16/18 , A61K39/395 , A61K2039/505 , C07K16/30 , C07K2317/76 , C07K2317/77 , C12N15/113 , C12N2310/14 , A61K2300/00
摘要: NLRR-1 antagonists and methods of their use in treating cancer and other disorders are provided.
摘要翻译: 提供NLRR-1拮抗剂及其用于治疗癌症和其它疾病的方法。
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公开(公告)号:US20120156194A1
公开(公告)日:2012-06-21
申请号:US13328830
申请日:2011-12-16
申请人: Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
发明人: Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC分类号: A61K39/395 , A61P11/06 , C07H21/04 , C07K16/18 , G01N33/577 , G01N33/566
CPC分类号: G01N33/6884 , A61K31/522 , A61K31/573 , A61K39/3955 , A61K39/39566 , A61K45/06 , C07K16/18 , C07K16/244 , C07K16/28 , G01N33/6887 , G01N33/6893 , G01N2333/475 , G01N2800/122 , G01N2800/52
摘要: Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
摘要翻译: 提供了诊断和治疗与TH2抑制有关的疾病的方法,包括但不限于哮喘。 还提供了选择或鉴定患者以治疗TH2途径抑制剂的某些治疗剂的方法。
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