公开(公告)号：US20140221368A1

公开(公告)日：2014-08-07

申请号：US14168629

申请日：2014-01-30

Applicant: Meso Scale Technologies, LLC

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew

IPC: G01N33/574 ,  A61K31/5377

CPC classification number: G01N33/57415 ,  A61K31/5377 ,  C12Q1/42 ,  C12Q1/485 ,  G01N2333/912 ,  G01N2333/916 ,  G01N2800/52

Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

Abstract translation: 本发明涉及诊断患者乳腺癌的方法，以及监测乳腺癌进展的方法和/或监测治疗剂或治疗方案治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。

公开(公告)号：US11467161B2

公开(公告)日：2022-10-11

申请号：US15386346

申请日：2016-12-21

Applicant: Meso Scale Technologies, LLC.

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew ,  Mingyue Wang

IPC: G01N33/574 ,  A61K31/44 ,  A61K31/404 ,  C12Q1/48

Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20170242012A1

公开(公告)日：2017-08-24

申请号：US15488743

申请日：2017-04-17

Applicant: Meso Scale Technologies, LLC.

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew

IPC: G01N33/574 ,  A61K31/5377

CPC classification number: G01N33/57415 ,  A61K31/5377 ,  C12Q1/42 ,  C12Q1/485 ,  G01N2333/912 ,  G01N2333/916 ,  G01N2800/52

Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20220299514A1

公开(公告)日：2022-09-22

申请号：US17667714

申请日：2022-02-09

Applicant: Meso Scale Technologies, LLC.

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew

IPC: G01N33/574 ,  A61K31/5377 ,  C12Q1/42 ,  C12Q1/48

Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen, The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US11327076B2

公开(公告)日：2022-05-10

申请号：US16157341

申请日：2018-10-11

Applicant: Meso Scale Technologies, LLC.

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew

IPC: G01N33/574 ,  A61K31/5377 ,  C12Q1/42 ,  C12Q1/48

Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20170205418A1

公开(公告)日：2017-07-20

申请号：US15386346

申请日：2016-12-21

Applicant: Meso Scale Technologies, LLC.

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew ,  Mingyue Wang

IPC: G01N33/574 ,  A61K31/404 ,  C12Q1/48 ,  A61K31/44

CPC classification number: G01N33/57438 ,  A61K31/404 ,  A61K31/44 ,  C12Q1/485 ,  G01N33/5743 ,  G01N2800/60

Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20140309263A1

公开(公告)日：2014-10-16

申请号：US14169308

申请日：2014-01-31

Applicant: Meso Scale Technologies, LLC

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew ,  Mingyue Wang

IPC: G01N33/574 ,  A61K31/404 ,  A61K31/44

CPC classification number: G01N33/57438 ,  A61K31/404 ,  A61K31/44 ,  C12Q1/485 ,  G01N33/5743 ,  G01N2800/60

Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

Abstract translation: 本发明涉及诊断患者肾脏疾病的方法，以及监测肾脏疾病进展的方法和/或监测治疗剂或治疗方案的治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。

公开(公告)号：US20220397579A1

公开(公告)日：2022-12-15

申请号：US17773896

申请日：2020-11-04

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Sunsanee Kanjananimmanont ,  Sudeep Kumar ,  Navaratnam Manjula ,  Simone Barbero ,  Martin Stengelin ,  George Sigal

IPC: G01N33/68 ,  G01N33/543

Abstract: The invention relates to methods and kits for quantitating radiation exposure in a subject exposed to radiation, at risk of exposure to radiation or suspected of having been exposed to radiation. In embodiments, the present disclosure provides multiplexed immunoassays for quantifying amounts of biomarkers for assessing radiation exposure in a sample. Also provided herein are kits for performing the multiplexed assays.

公开(公告)号：US20220196668A1

公开(公告)日：2022-06-23

申请号：US17693918

申请日：2022-03-14

Applicant: Meso Scale Technologies, LLC.

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew ,  Mingyue Wang

IPC: G01N33/574 ,  A61K31/44 ,  A61K31/404 ,  C12Q1/48

Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20190265243A1

公开(公告)日：2019-08-29

申请号：US16157341

申请日：2018-10-11

Applicant: Meso Scale Technologies, LLC.

Inventor： Simone Barbero ,  Eli N. Glezer ,  Anu Mathew

IPC: G01N33/574 ,  C12Q1/42 ,  C12Q1/48 ,  A61K31/5377

Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.