公开(公告)号：US10398364B2

公开(公告)日：2019-09-03

申请号：US14767698

申请日：2014-02-13

申请人： MESPERE LIFESCIENCES INC.

发明人： Xuefeng Cheng

IPC分类号： A61B5/00 ,  A61B5/1455 ,  A61B5/0295 ,  A61B5/024 ,  A61B5/021 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/029

摘要： A device for non-invasively measuring at least one parameter of a cardiac blood vessel in a patient comprises at least one light source that directs light at a tissue site on the patient; at least one photodetector adapted to receive light emitted by the light source and generate an output based on the received light, the output of said photodetector being correlated with a parameter of the blood vessel; and at least one probe for facilitating delivery of light from the light source to the tissue site, and receipt of light by the photodetector. The device may include a height sensor to adapt it for use to determine central venous pressure, or the configuration of light source(s) and photodetector(s) may be adapted to permit the device to provide attenuation correction in the determination of venous blood oxygenation.

公开(公告)号：US08788005B1

公开(公告)日：2014-07-22

申请号：US13913911

申请日：2013-06-10

申请人： Mespere Lifesciences Inc.

发明人： Xuefeng Cheng

IPC分类号： A61B5/00

CPC分类号： A61B5/6833 ,  A61B5/14553

摘要： A method and system are provided which are useful for the non-invasive determination and monitoring of cerebral blood oxygenation in a patient. The system comprises a first module for optically generating at least first and second internal jugular venous output signals against time at at least first and second wavelengths of light; and a second module for generating first and second cardiac arterial output signals at the first and second wavelengths of light, respectively. The system may additionally include a third module for optically generating at least first and second external jugular venous output signals against time at at least first and second wavelengths of light, and one or more cerebral modules for optically generating at least first and second local cerebral output signals against time at at least first and second wavelengths of light. The system includes a signal processing means adapted to calculate average cerebral, arterial, venous scalp and local cerebral blood oxygenation values based on the output from each of the modules.

摘要翻译： 提供了一种方法和系统，其可用于非侵入性测定和监测患者的脑血氧饱和度。 该系统包括用于在至少第一和第二波长的光下相对于时间光学地产生至少第一和第二颈内静脉输出信号的第一模块; 以及用于分别在所述第一和第二波长的光下产生第一和第二心脏动脉输出信号的第二模块。 该系统可以另外包括第三模块，用于在至少第一和第二波长的光下相对于时间光学地产生至少第一和第二外部颈静脉输出信号，以及一个或多个脑模块，用于光学地产生至少第一和第二局部大脑输出 信号在至少第一和第二波长的光的时间。 该系统包括适于基于每个模块的输出来计算平均脑，动脉，静脉头皮和局部脑血氧值的信号处理装置。

公开(公告)号：US20170100044A1

公开(公告)日：2017-04-13

申请号：US15288275

申请日：2016-10-07

申请人： Mespere Lifesciences Inc.

发明人： Xuefeng Cheng

IPC分类号： A61B5/021 ,  A61B5/00

摘要： A system for measuring central venous pressure is provided comprising a device for measuring jugular venous pressure in communication with a patient inclination controller via a processing unit.

公开(公告)号：US11096598B2

公开(公告)日：2021-08-24

申请号：US15288275

申请日：2016-10-07

申请人： Mespere Lifesciences Inc.

发明人： Xuefeng Cheng

IPC分类号： A61B5/021 ,  A61B5/00 ,  A61B5/0215 ,  A61G13/04

摘要： A system for measuring central venous pressure is provided comprising a device for measuring jugular venous pressure in communication with a patient inclination controller via a processing unit.

公开(公告)号：US08918153B2

公开(公告)日：2014-12-23

申请号：US13765843

申请日：2013-02-13

申请人： Mespere Lifesciences Inc.

发明人： Xuefeng Cheng

IPC分类号： A61B5/00 ,  A61B5/021 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/029 ,  A61B5/1455

CPC分类号： A61B5/021 ,  A61B5/0205 ,  A61B5/02116 ,  A61B5/0261 ,  A61B5/029 ,  A61B5/14551 ,  A61B5/6822 ,  A61B2560/0261 ,  A61B2562/0233 ,  A61B2562/046

摘要： A device for non-invasively measuring at least one parameter of a cardiac blood vessel in a patient is provided. The device comprises at least one light source that emits light in the 400 nm to 1000 nm wavelength range; at least one photodetector adapted to receive light emitted by the light source and generate an output based on the received light, wherein said light is reflected from or transmitted through tissue of the patient, the output of said photodetector being correlated with a parameter of the blood vessel; and at least one probe for facilitating delivery of light from the light source to an external tissue site on the patient in the proximity of the cardiac blood vessel and receipt of light by the photodetector. A system and methods of monitoring/measuring cardiac parameters utilizing the device and/or system are also provided.

摘要翻译： 提供了用于非侵入性地测量患者心脏血管的至少一个参数的装置。 该装置包括发射400nm至1000nm波长范围内的光的至少一个光源; 至少一个光电检测器适于接收由光源发射的光并基于所接收的光产生输出，其中所述光从患者的组织反射或透过，所述光电检测器的输出与血液的参数相关 船只; 以及至少一个探针，用于促进光从光源传递到心脏血管附近的患者的外部组织部位，并且由光电检测器接收光。 还提供了利用设备和/或系统监测/测量心脏参数的系统和方法。