公开(公告)号：US20240358860A1

公开(公告)日：2024-10-31

申请号：US18770135

申请日：2024-07-11

Applicant: The General Hospital Corporation

Inventor： Conor L. Evans ,  Gabriela Apiou ,  Alexander J. Nichols ,  Emmanouil Rousakis ,  Zongxi Li

IPC: A61K49/00 ,  A61B5/00 ,  A61B5/1455 ,  A61B90/00 ,  A61F13/00 ,  C07D487/22

CPC classification number: A61K49/0015 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/14556 ,  A61B5/443 ,  A61B5/6833 ,  A61B90/39 ,  C07D487/22 ,  A61B5/0022 ,  A61B5/4839 ,  A61B5/743 ,  A61B2562/12 ,  A61F2013/0097

Abstract: Compounds, systems, and methods are provided for the design and assembly of a non-invasive, analyte sensing dressing. The dressing can be therapeutic. The dressing includes a sensor and a matrix. The sensor is capable of detecting analytes such as molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma, and hydrogen ions. The matrix is at least partially permeable to the analyte. The device emits a detectable signal when the sensor is excited in the presence of the analyte. In one version of the dressing, the sensor includes a meso-unsubstituted metallated porphyrin that is sensitive towards oxygen. The metallated porphyrin can be excited when illuminated at a first wavelength, followed by emission of phosphorescence at a second wavelength whose intensity can be used as an indicator for oxygen concentration.

公开(公告)号：US20240358291A1

公开(公告)日：2024-10-31

申请号：US18630426

申请日：2024-04-09

Applicant: Covidien LP

Inventor： Sarah L. Hayman ,  Devon E. Scott-Drechsel ,  Liana J. Kerr-Layton ,  Mia D. Fox ,  Nicholas J. Vaver ,  Catalina S. Bastías Díaz ,  Kathleen C. Stewart

IPC: A61B5/1455 ,  A61B5/00 ,  A61B90/00

CPC classification number: A61B5/14552 ,  A61B5/6814 ,  A61B5/6833 ,  A61B5/68335 ,  A61B90/08 ,  A61B2090/0807 ,  A61B2562/164

Abstract: In some examples, a kit includes a pulse oximetry sensor patch and a stretchable pressure backing configured to be applied to a region of a patient's skin. An assembly may include the stretchable pressure backing securing the pulse oximetry sensor patch against the patient's skin. The stretchable pressure backing is configured to stretch across the pulse oximetry sensor patch from an unstretched length to a stretched length. When in its stretched length, the stretchable pressure backing is configured to press the pulse oximetry sensor patch against the patient's skin to apply pressure to reduce venous pulsations in the region of the patient's skin. An example technique includes applying the pulse oximetry sensor patch to the patient's skin and stretching the stretchable pressure backing across the pulse oximetry sensor patch to its stretched length to apply pressure to the pulse oximetry sensor patch to reduce venous pulsations.

公开(公告)号：US20240358279A1

公开(公告)日：2024-10-31

申请号：US18771659

申请日：2024-07-12

Applicant: BLINK DEVICE LLC

Inventor： Justin HULVERSHORN ,  Karl SCHMIDT ,  Tyler HART

IPC: A61B5/11 ,  A61B5/00 ,  A61B5/24 ,  A61B5/294 ,  A61B5/296 ,  A61B5/305 ,  A61B5/388 ,  A61B5/389 ,  A61B5/395 ,  A61N1/04 ,  G16H10/60 ,  G16H50/20

CPC classification number: A61B5/1106 ,  A61B5/24 ,  A61B5/296 ,  A61B5/305 ,  A61B5/388 ,  A61B5/389 ,  A61B5/395 ,  A61B5/6824 ,  A61B5/6826 ,  A61B5/6833 ,  A61B5/685 ,  A61B5/7217 ,  A61B5/294 ,  A61B2560/0238 ,  A61B2562/0219 ,  A61N1/0456 ,  G16H10/60 ,  G16H50/20

Abstract: Neuromuscular monitoring is described that uses a novel lead assembly and a monitor that can select the appropriate electrodes on the lead assembly and calibrate the stimulation signals applied to the patient through the lead assembly. The monitoring can also set a noise floor value to reduce the likelihood of an erroneous train of four ratio.

公开(公告)号：US20240341735A1

公开(公告)日：2024-10-17

申请号：US18422723

申请日：2024-01-25

Applicant: CoreSyte, Inc.

Inventor： Adam Pizer ,  Dalton Pont ,  John V. Chiochetti

IPC: A61B10/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1477 ,  B23K1/00 ,  B23K1/008 ,  B23K26/38 ,  B23K26/382 ,  B23K26/384 ,  B23K26/402 ,  B23K101/36 ,  B23K101/42 ,  B23K103/00 ,  B23K103/16 ,  B29C69/00 ,  B29K27/06 ,  B29L9/00 ,  B29L31/00 ,  B29L31/34 ,  G01N33/487 ,  H05K1/16

CPC classification number: A61B10/0064 ,  A61B5/14517 ,  A61B5/1477 ,  A61B5/4266 ,  A61B5/6833 ,  B23K1/0016 ,  B23K1/008 ,  B23K26/38 ,  B23K26/384 ,  B23K26/389 ,  B23K26/402 ,  B29C69/00 ,  G01N33/48707 ,  A61B2562/0295 ,  A61B2562/12 ,  A61B2562/125 ,  A61B2562/164 ,  A61B2562/166 ,  B23K2101/36 ,  B23K2101/42 ,  B23K2103/172 ,  B23K2103/42 ,  B29K2027/06 ,  B29K2995/0005 ,  B29L2009/008 ,  B29L2031/34 ,  B29L2031/753 ,  H05K1/16 ,  H05K2201/10151

Abstract: The present invention presents a method of fabrication for a physiological sensor with electronic, electrochemical, and chemical components. The fabrication method comprises steps for manufacturing an apparatus comprising at least one electrochemical sensor, a microcontroller, and a transceiver. The fabrication process includes the steps of substrate fabrication, circuit fabrication, pick and place, reflow soldering, electrode fabrication, membrane fabrication, sealing and curing, layer bonding, and dressing. The physiological sensor is operable to analyze biological fluids such as sweat.

公开(公告)号：US20240341685A1

公开(公告)日：2024-10-17

申请号：US18647155

申请日：2024-04-26

Applicant: LIFESIGNALS, INC.

Inventor： Surendar MAGAR

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/0245 ,  A61B5/08 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  A61B7/04

CPC classification number: A61B5/6833 ,  A61B5/0022 ,  A61B5/02055 ,  A61B5/112 ,  A61B5/14542 ,  A61B5/165 ,  A61B5/4818 ,  A61B5/4875 ,  A61B5/681 ,  A61B5/7264 ,  A61B5/742 ,  A61B7/04 ,  A61B5/02405 ,  A61B5/0245 ,  A61B5/0816 ,  A61B2503/04 ,  A61B2503/08 ,  A61B2503/40 ,  A61B2560/0443 ,  A61B2562/0219

Abstract: A compact integrated patch may be used to collect physiological data. The patch may be wireless. The patch may comprise a plurality of sensors, each sensor configured to collect different health related data from a subject to which the patch is attached, and a communication interface configured to wirelessly and directly communicate with a mobile device, wherein the mobile device is capable of running a plurality of applications, wherein each application of said plurality is configured to utilize data from different subsets of sensors from the plurality of sensors, to provide different monitoring activities for the subject. The patch may be utilized in everyday life as well as in clinical environments.

公开(公告)号：US20240335144A1

公开(公告)日：2024-10-10

申请号：US18681494

申请日：2022-06-02

Applicant: I-SENS, INC.

Inventor： Hyun Ho CHOI ,  Goang Yel RYU ,  Ji Hoon WANG

IPC: A61B5/145 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/14503 ,  A61B5/6833 ,  A61B2560/045 ,  A61B2560/0462

Abstract: An applicator according to the present disclosure is an applicator for inserting a sensor for measuring biometric information into a user's skin, and comprises: an applicator body; an insertion unit installed in the applicator body to move a sensor unit including the sensor and a sensor unit housing in which the sensor is mounted, from a first position spaced apart from the user's skin to a second position where the sensor is inserted into the user's skin; an operating member installed on the applicator body so as to be manipulated by a user; and a stopper member installed on the applicator body so as to operate the insertion unit in conjunction with the operating member, wherein the insertion unit has a shuttle that moves from the first position to the second position together with the sensor unit, and the stopper member engages with the shuttle after the shuttle moves to the second position to restrict the movement of the shuttle such that the shuttle does not return to the first position.

公开(公告)号：US12109033B1

公开(公告)日：2024-10-08

申请号：US16983691

申请日：2020-08-03

Applicant: VivaQuant LLC

Inventor： Garrett Duffy ,  Brian Brockway ,  Jonathan Engel ,  Marina Brockway

IPC: A61B5/318 ,  A61B5/00 ,  A61B5/282 ,  A61B5/30 ,  A61B5/366

CPC classification number: A61B5/366 ,  A61B5/0006 ,  A61B5/282 ,  A61B5/30 ,  A61B5/6833 ,  A61B5/7203 ,  A61B2560/0214 ,  A61B2560/0406

Abstract: As may be implemented in accordance with one or more aspects depicted herein, an apparatus and/or method involves monitoring heart rhythm of a patient utilizing a housing having amplifying circuitry and digitizing circuitry configured to amplify and digitize ECG signals. Two or more legs protrude from the housing, each configured to provide an electrical connection from an ECG electrode to the amplifying circuitry. Computing circuitry processes the digitized ECG signals, communication circuitry communicates data corresponding to the ECG signals, and data storage circuitry stores data corresponding to the ECG signals. A charge storage circuit provides power to the circuitry, computing circuitry, and communication circuitry. The legs mechanically connect to skin electrodes and to support the weight of the housing and its contents in response to the skin electrodes being adhesively secured to skin.

公开(公告)号：US12102425B2

公开(公告)日：2024-10-01

申请号：US17121309

申请日：2020-12-14

Applicant: TRACPATCH HEALTH, LLC

Inventor： Ralph J. Mobbs ,  Curt Wiedenhoefer ,  Graeme Phillip McMeekan ,  Anthony J. Habib

IPC: A61B5/00 ,  A61B5/11

CPC classification number: A61B5/1117 ,  A61B5/0004 ,  A61B5/112 ,  A61B5/486 ,  A61B5/6833 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B2562/0219

Abstract: A system for monitoring a user that includes a sensor unit configured and arranged to be disposed on the user, the sensor unit including an accelerometer and a communication arrangement; and at least one processor configured and arranged for performing actions including: receiving signals from the accelerometer of the sensor unit; determining a step count from the signals; determining a gait velocity from the signals; determining a step distance from the signals; determining a posture of the user from the signals; and determining a gait posture index as a function of the step count, gait velocity, step distance, and posture. In other embodiments, the system can be used to determine metrics other than the gait posture index, such as a fall prediction score based on gait velocity and posture deviation.

公开(公告)号：US12097011B1

公开(公告)日：2024-09-24

申请号：US18517879

申请日：2023-11-22

Applicant: John Hanks ,  Amir Tofighi Zavareh ,  Limei Tian

Inventor： John Hanks ,  Amir Tofighi Zavareh ,  Limei Tian

IPC: A61B5/01 ,  A61B5/00 ,  G01K13/20 ,  G06N20/00 ,  G16H50/20

CPC classification number: A61B5/01 ,  A61B5/6833 ,  A61B5/7275 ,  G06N20/00 ,  G16H50/20 ,  A61B2560/0252 ,  A61B2560/0285 ,  A61B2560/0462 ,  A61B2562/0271 ,  A61B2562/046 ,  A61B2562/125 ,  A61B2562/164 ,  G01K13/20

Abstract: Provided herein are thermal devices and single-use temperature measurement devices to predict and to monitor core body temperature in a subject, such as a patient. The devices utilize a plurality of thermal or temperature sensors disposed on a patch and insulated one from the other and a connection to a machine learning algorithm for prediction and monitoring. Also provided are systems and methods using the thermal device or temperature monitoring device and the machine learning algorithm to predict and measure core body temperature in the subject.

公开(公告)号：US20240298932A1

公开(公告)日：2024-09-12

申请号：US18664947

申请日：2024-05-15

Applicant: Medtronic MiniMed, Inc.

Inventor： Ashwin K. Rao ,  Rebecca K. Gottlieb ,  Quyen B. Ong

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1477 ,  A61B5/1486 ,  C07K14/62 ,  C12Q1/00 ,  G01N33/52 ,  G01N33/66

CPC classification number: A61B5/14532 ,  A61B5/14517 ,  A61B5/1486 ,  G01N33/526 ,  G01N33/66 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/6833 ,  C07K14/62 ,  C12Q1/006

Abstract: Described here are patches and methods for measuring glucose in sweat (and tears and the like). In general, the patches comprise an adhesive layer adapted to bond to skin of an individual, a substrate layer disposed over the adhesive layer and comprising a glucose sensing complex including a chromogen that changes color in the presence of certain concentrations of glucose, and a cover. In typical embodiments, the substrate layer has elements formed to direct and accumulate sweat that migrates from the skin of the individual to the glucose sensing complex. Methods of using the invention can comprise cleaning the skin surface, collecting sweat in a patch comprising this microfluidic constellation of elements, and observing concentrations of glucose collected in the sweat, for example either visually, or by using a smartphone or other computer processing device.