摘要:
Provided is a method for identifying relevant groups of genes using gene expression profiles. More particularly, it is provided a method for identifying relevant groups of genes using gene expression profiles, which analyzes the gene expression profiles obtained from microarray experiments to automatically extract seed genes of significance and identifies the relevant groups of genes based on the extracted seed genes, so that effective identification is possible regardless of the number of genes and a blind setting of initial input parameters are not required for users to readily use the method, wherein the method comprises the steps of (a) preprocessing the gene expression profiles; (b) setting the number of gene groups to be desired (k) and a input parameter(s); (c) extracting k seed genes (k=1, 2, 3, . . . ,n) based on the set input parameter(s); (d) identifying relevant groups of genes by means of the extracted seed genes; and (e) evaluating the identified relevant groups of genes.
摘要:
The invention relates to a method for manufacturing dielectric ceramic powder and a multilayer ceramic capacitor using the ceramic powder. According to the invention, BaCO3 powder is dispersed into a solution of solvent and dispersant to prepare BaCO3 slurry and then the resultant BaCO3 slurry is wet-milled. Also, TiO2 powder slurry is mixed into the wet-milled BaCO3 slurry to form mixed slurry and then the mixed slurry is dried into mixed powder. Finally, the dried mixed powder is calcined to produce BaTiO3 powder.
摘要:
A biological relationship extraction system including a biological named entity substitution unit substituting a biological named entity in a biological document with a predetermined substitution name; a structure analyzing unit parsing the biological named entity in the biological document containing the substituted biological named entity; a relationship analyzing unit analyzing a relationship between biological named entities from the biological literature parsed by the structure analyzing unit and selecting relationship candidates; a relationship determining unit determining whether the relationship candidates delivered from the relationship analyzing unit are biologically meaningful and determining a relationship between biological named entities; and a biological named entity assignment storage unit storing the biological named entity and a substitution name corresponding to the biological named entity and providing a substitution name or a biological named entity.
摘要:
Provided is a method for conceptualizing protein interaction networks. The method conceptualizes and simplifies complicated and enormous protein interaction networks wherein the method comprises the steps of (a) conceptualizing protein nodes that form the protein interaction network as gene ontology concepts to reconfigure the network; (b) integrating nodes including the same concepts in the reconfigured network into one node to generate the network by means of exact match; and (c) integrating several nodes having similar concepts in the generated network into one node to reconfigure the generated network by means of approximate match.
摘要:
Provided are a method and system for verifying a protein-protein interaction according to a text mining method. The method includes extracting protein-protein interaction information from protein-related documents searched for from a bio-information document database, according to a text mining method, mapping the protein-protein interaction information to corresponding ontology identifications, and filtering the mapped protein-protein interaction information according to a frequency of the information and an impact factor of a corresponding protein-related document in order to obtain highly-weighted information.
摘要:
Provided are a method and apparatus for predicting a regulation of multiple transcription factors which can predict a regulation correlation between the multiple transcription factors and a target gene, wherein the regulation correlation is used in a method of manipulating a gene inside an actual cell. The method includes: separating gene expression profile data into expression profile data of a gene which expresses a transcription factor and an expression profile data of a target gene; clustering all pairs which can be combined, one pair including one transcription factor and one target gene; showing a result of the clustering using an interval graph; and calculating a optimum subset of the transcription factors, which occupies the maximum expression section of the target gene with the minimum number of transcription factors.
摘要:
An apparatus and method for searching for a protein active site by using a bottom-hat transformation are provided. First, an image of protein surface is generated and then a volumetric image is generated by sampling the protein surface in units of a predetermined length. Thereafter a morphology process is performed on the volumetric image, thereby extracting the protein active site from the morphology-processed volumetric image. Accordingly, it is possible to rapidly search for a protein active site in a 3D structural space.
摘要:
A method for generating a database schema in order to generate an integrated view capable of obtaining desired data from data resources dispersed and stored in different formats in different locations, and an data integrating system are provided. The method includes rules for parsing the structure and contents of an database described in a specification language, generating a schema semantically corresponding to the database, and defining data items required for generating an integrated view. Also, in order to generate a global schema expressing an integrated view, part of XQuery grammar is introduced for local schemas expressing a single database, and a definition of standard expression for expressing a data view is included. Accordingly, an data integrating system can generate an integrated view for a variety of heterogeneous databases dispersed on a network by using a specification language, and post a query in real time.
摘要:
Provided are an information query extension system and method, and more particularly, a method for efficiently managing heterogeneous data using a defined specification language to represent information distributed on the Internet, and extending a conceptual query which is a criteria for integration for a specific purpose.
摘要:
Provided is a system for and method of extracting and clustering information. The system includes a clustering criterion designing unit that reconstructs a plurality of clustering criteria for each layer or applies weights to the plurality of clustering criteria in order to design a new clustering criterion, an input data processing unit that extracts characteristics from input data according to the new clustering criterion, and a clustering unit that performs clustering on the extracted characteristics.