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公开(公告)号：US20090169537A1
公开(公告)日：2009-07-02
申请号：US12300209
申请日：2007-05-10
申请人： Michael Bausch , Rainer Wetzler , Christian Müller
发明人： Michael Bausch , Rainer Wetzler , Christian Müller
CPC分类号： A61K38/50 , A61K31/198 , A61K2300/00
摘要： The present invention relates to a pharmaceutical combination product for cancer therapy. The combination product comprises the two active ingredients glutaminase and 6-diazo-5-oxo-L-norleucine (DON). The invention further relates to the use of such a combination product for the treatment of cancers.
摘要翻译： 本发明涉及用于癌症治疗的药物组合产品。 组合产品包含两种活性成分谷氨酰胺酶和6-重氮-5-氧代-L-正亮氨酸（DON）。 本发明还涉及这种组合产品用于治疗癌症的用途。
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公开(公告)号：US08465736B2
公开(公告)日：2013-06-18
申请号：US12300209
申请日：2007-05-10
申请人： Michael Bausch , Wetzler Rainer , Christian Muller
发明人： Michael Bausch , Wetzler Rainer , Christian Muller
IPC分类号： A61K38/48
CPC分类号： A61K38/50 , A61K31/198 , A61K2300/00
摘要： The present invention relates to a pharmaceutical combination product for cancer therapy. The combination product comprises the two active ingredients glutaminase and 6-diazo-5-oxo-L-norleucine (DON). The invention further relates to the use of such a combination product for the treatment of cancers.
摘要翻译： 本发明涉及用于癌症治疗的药物组合产品。 组合产品包含两种活性成分谷氨酰胺酶和6-重氮-5-氧代-L-正亮氨酸（DON）。 本发明还涉及这种组合产品用于治疗癌症的用途。
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公开(公告)号：US20090048682A1
公开(公告)日：2009-02-19
申请号：US11893855
申请日：2007-08-17
申请人： Andy Wonyong Choi , Philip Bryan , Michael Bausch , Scott Kennard
发明人： Andy Wonyong Choi , Philip Bryan , Michael Bausch , Scott Kennard
CPC分类号： A61F2/36 , A61F2/40 , A61F2/4637 , A61F2/4684 , A61F2002/30331 , A61F2002/30332 , A61F2002/305 , A61F2002/30616 , A61F2002/3611 , A61F2002/3625 , A61F2002/365 , A61F2002/3652 , A61F2002/4641 , A61F2220/0025 , A61F2220/0033
摘要： The system to implant a prosthetic device in a long bone such as a femur or a humerus includes a stem implant having a recess. The system of present invention also includes a broach to prepare the long bone that may receive the stem implant. The broach also has a recess that is similar to the recess in the stem implant. An adapter of a generally rectangular shape similar to the recess fits snugly in the recess in the stem implant. A trial neck that fits snugly in the recess formed in the adapter is also provided. A trial head may be assembled on the trial neck. A neck similar to the trial neck can be inserted in place of trial neck. A head may be assembled on the proximal end of the neck. A system for implantation of a prosthetic device in a long bone may be made available as a kit that includes at least two stems having the adapter inserted in each of the stem, at least two trial necks, at least two trial heads, at least two necks and at least two heads.
摘要翻译： 将假体装置植入长骨（例如股骨或肱骨）中的系统包括具有凹部的柄植入物。 本发明的系统还包括用于准备可以接收柄植入物的长骨的拉刀。 拉刀还具有类似于柄植入物中的凹部的凹部。 类似于凹部的大致矩形形状的适配器紧贴地配合在柄植入物的凹部中。 还提供了紧贴在适配器中形成的凹部中的试验颈部。 审判人员可以在审判脖子上组装。 可以插入类似于试验颈部的颈部代替试管颈。 头部可以组装在颈部的近端上。 用于在长骨中植入假体装置的系统可以作为试剂盒获得，该试剂盒包括至少两个茎，其具有插入每个茎中的适配器，至少两个试验颈部，至少两个试验头，至少两个 颈部和至少两个头。
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公开(公告)号：US20050196191A1
公开(公告)日：2005-09-08
申请号：US11115362
申请日：2005-04-27
申请人： Michael Bausch , Mary Dailor , David Hudson , Scott Miller , Michael Schneier , Martin Schooping
发明人： Michael Bausch , Mary Dailor , David Hudson , Scott Miller , Michael Schneier , Martin Schooping
IPC分类号： G03G15/08
CPC分类号： G03G15/0894 , G03G15/0855 , G03G15/0865 , G03G15/0875 , G03G2215/068 , G03G2215/0692 , G03G2215/0875
摘要： A developer cartridge for containing a developer and for delivering the developer to a developer hopper of an electro-photographic machine. A developer containment portion includes a first portion having an at least partially closed volume configured to contain the developer and a second portion adjacent the first portion and having an opening configured to deliver the developer to the developer hopper. A sealing gasket is disposed adjacent the second portion of the developer containment portion and surrounds at least a portion of a circumference of the opening. A first cover is disposed adjacent the second portion of the developer containment portion and is positionable between an open position for delivery of the developer and a closed position for preventing delivery of the developer. The sealing gasket contacts the first cover to prevent undesired leakage of the developer therebetween.
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公开(公告)号：US20050027168A1
公开(公告)日：2005-02-03
申请号：US10897455
申请日：2004-07-23
申请人： John Strom , Cynthia Kuiper , Chris Roberts , Michael Bausch , Allan Krauter , Eric Andreassen , David Woods
发明人： John Strom , Cynthia Kuiper , Chris Roberts , Michael Bausch , Allan Krauter , Eric Andreassen , David Woods
CPC分类号： A61B1/227
摘要： A tip element for an otoscopic apparatus includes engagement features that permit selective attachment to two different tip attachment mechanisms. The tip element includes both interior and exterior engagement features that provide interchangeability with otoscopes having different tip attachment schemes. The tip element includes an increased distal aperture formed from a decreased slope that enables a larger field of view, permitting the entire tympanic membrane to be viewed at once. External engagement features permit ejection of the tip from the otoscope, as well as stackability of a plurality of tip elements.
摘要翻译： 用于耳镜装置的尖端元件包括允许选择性地附接到两个不同尖端附接机构的接合特征。 尖端元件包括提供与具有不同尖端附接方案的耳镜的互换性的内部和外部接合特征。 尖端元件包括由减小的斜率形成的增加的远端孔，其能够获得更大的视野，允许立即观察整个鼓膜。 外部接合特征允许尖端从耳镜弹出，以及多个尖端元件的可堆叠性。
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公开(公告)号：US07981161B2
公开(公告)日：2011-07-19
申请号：US11893855
申请日：2007-08-17
申请人： Andy Wonyong Choi , Philip Bryan , Michael Bausch , Scott Kennard
发明人： Andy Wonyong Choi , Philip Bryan , Michael Bausch , Scott Kennard
IPC分类号： A61F2/32
CPC分类号： A61F2/36 , A61F2/40 , A61F2/4637 , A61F2/4684 , A61F2002/30331 , A61F2002/30332 , A61F2002/305 , A61F2002/30616 , A61F2002/3611 , A61F2002/3625 , A61F2002/365 , A61F2002/3652 , A61F2002/4641 , A61F2220/0025 , A61F2220/0033
摘要： The system to implant a prosthetic device in a long bone such as a femur or a humerus includes a stem implant having a recess. The system of present invention also includes a broach to prepare the long bone that may receive the stem implant. The broach also has a recess that is similar to the recess in the stem implant. An adapter of a generally rectangular shape similar to the recess fits snugly in the recess in the stem implant. A trial neck that fits snugly in the recess formed in the adapter is also provided. A trial head may be assembled on the trial neck. A neck similar to the trial neck can be inserted in place of trial neck. A head may be assembled on the proximal end of the neck. A system for implantation of a prosthetic device in a long bone may be made available as a kit that includes at least two stems having the adapter inserted in each of the stem, at least two trial necks, at least two trial heads, at least two necks and at least two heads.
摘要翻译： 将假体装置植入长骨（例如股骨或肱骨）中的系统包括具有凹部的柄植入物。 本发明的系统还包括用于准备可以接收柄植入物的长骨的拉刀。 拉刀还具有类似于柄植入物中的凹部的凹部。 类似于凹部的大致矩形形状的适配器紧贴地配合在柄植入物的凹部中。 还提供了紧贴在适配器中形成的凹部中的试验颈部。 审判人员可以在审判脖子上组装。 可以插入类似于试验颈部的颈部代替试管颈。 头部可以组装在颈部的近端上。 用于在长骨中植入假体装置的系统可以作为试剂盒获得，该试剂盒包括至少两个茎，其具有插入每个茎中的适配器，至少两个试验颈部，至少两个试验头，至少两个 颈部和至少两个头。
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