公开(公告)号：US20100217227A1

公开(公告)日：2010-08-26

申请号：US12578342

申请日：2009-10-13

申请人： Michael Braun ,  John S. Geis ,  Todd F. Davenport

发明人： Michael Braun ,  John S. Geis ,  Todd F. Davenport

IPC分类号： A61L31/16 ,  A61M25/00

CPC分类号： A61L27/56 ,  A61L29/146 ,  A61L31/146

摘要： A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.A novel medical wire is also disclosed herein.

摘要翻译： 一种系统，包括：中空管，其具有远端，近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的富含气体的全氟化碳溶液; 其中所述多孔膜的孔隙率在0.001-200微米的范围内，以便：（i）富气体全氟化碳溶液有效地并入多孔膜中; 和（ii）当多孔膜位于血液中时，富含气体的全氟化碳溶液以足够小的聚集体从多孔膜中洗脱出来，以防止在血液中产生栓塞，同时溶解富含气体的全氟化碳溶液 根据血液的温度和血液动力学，血液在几分钟到几个小时之间变化。 本文还公开了一种新颖的医用电线。

公开(公告)号：US20090326508A1

公开(公告)日：2009-12-31

申请号：US12472759

申请日：2009-05-27

申请人： Michael Braun ,  John S. Geis ,  Todd F. Davenport

发明人： Michael Braun ,  John S. Geis ,  Todd F. Davenport

IPC分类号： A61M25/10 ,  A61M25/09

CPC分类号： A61M25/0009 ,  A61M25/104 ,  A61M2025/0057 ,  A61M2025/105

摘要： A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a pharmacological agent incorporated in the porous membrane; wherein the porous membrane has a porosity such that: (i) the pharmacological agent is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the pharmacological agent elutes out of the porous membrane at a rate which matches the desired rate of dosage for the pharmacological agent.

摘要翻译： 一种系统，包括：中空管，其具有远端，近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的药剂; 其中所述多孔膜具有孔隙率，使得：（i）所述药理学试剂有效地并入所述多孔膜中; 和（ii）当多孔膜位于血液中时，药理学试剂以与药物剂的所需剂量速率相匹配的速率从多孔膜中洗出。

公开(公告)号：US20090054878A1

公开(公告)日：2009-02-26

申请号：US11895249

申请日：2007-08-23

申请人： John S. Geis ,  Michael Braun

发明人： John S. Geis ,  Michael Braun

IPC分类号： A61B17/00

CPC分类号： A61B50/30

摘要： The invention relates to a device for introducing a medical instrument into a closed container (2). The device is characterized in that it has a penetration means (11) for penetration of a container wall and a guiding unit (12) is adjacent to the penetration means (11), wherein the penetration means (11) and the guiding unit (12) have a common passage (10) for the introduction of a medical instrument (3) and the passage (10) has at least temporarily a narrowing.

摘要翻译： 本发明涉及一种用于将医疗器械引入密闭容器（2）中的装置。 该装置的特征在于其具有用于穿透容器壁的穿透装置（11），并且引导单元（12）邻近穿透装置（11），其中穿透装置（11）和引导单元（12） ）具有用于引入医疗器械（3）的共同通道（10），并且通道（10）至少暂时变窄。

公开(公告)号：US06511497B1

公开(公告)日：2003-01-28

申请号：US09661461

申请日：2000-09-13

申请人： Michael Braun ,  John S. Geis

发明人： Michael Braun ,  John S. Geis

IPC分类号： A61M2900

CPC分类号： A61F2/013 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067

摘要： The present invention comprises a vascular filter system for non-permanent application which is provided with a guide wire, a filter membrane having an inner area provided in the area of the proximal end of the guide wire and a free outer area, and an umbrella structure provided at least on the outer area of the filter membrane, made of a flexible material and permitting opening and closing of the umbrella formed by the umbrella structure and filter membrane, characterized in that the system has contactless structure for closing the umbrella. The structure can be of a magnetic nature or involve mechanisms based on temperature changes.

摘要翻译： 本发明包括一种用于非永久性应用的血管过滤系统，其具有引导线，滤膜，其具有设置在导丝的近端区域中的内部区域和自由外部区域，以及伞形结构 至少设置在由柔性材料制成的过滤膜的外部区域上，并且允许由伞形结构和过滤膜形成的伞的打开和关闭，其特征在于，所述系统具有用于关闭伞的非接触结构。 该结构可以具有磁性，或涉及基于温度变化的机理。

公开(公告)号：US20090076449A1

公开(公告)日：2009-03-19

申请号：US11884666

申请日：2006-02-15

申请人： John S. Geis ,  Michael Braun ,  Adalbert Kovacs ,  Gerhard K. Wolf

发明人： John S. Geis ,  Michael Braun ,  Adalbert Kovacs ,  Gerhard K. Wolf

IPC分类号： A61M29/00 ,  A61M25/00

CPC分类号： A61M25/0009 ,  A61B2017/00853 ,  A61M25/0045 ,  A61M25/10 ,  A61M2025/0057 ,  A61M2025/105 ,  A61M2025/1081

摘要： The invention relates to a cover (1) for a medical instrument (3), which is characterized in that the cover (1) is a generally pipe-shaped body and consists of one single tape (11) which extends generally helicoidally about the axis of the pipe-shaped body. The invention furthermore relates to a process for applying a cover (1) onto a medical instrument (3) as well as to a medical instrument (3) which is provided with a cover (1).

摘要翻译： 本发明涉及一种用于医疗器械（3）的盖（1），其特征在于，所述盖（1）是大致管状的主体，并且由一个单独的带（11）构成，所述单个带 的管状体。 本发明还涉及将盖（1）施加到医疗器械（3）以及设置有盖（1）的医疗器械（3）的方法。

公开(公告)号：US20090216200A1

公开(公告)日：2009-08-27

申请号：US11885976

申请日：2006-03-13

申请人： John S. Geis ,  Michael Braun

发明人： John S. Geis ,  Michael Braun

IPC分类号： A61M25/14

CPC分类号： A61M25/0043 ,  A61M2025/0042 ,  A61M2025/0057

摘要： The present invention relates to a system for introduction of an agent into a blood vessel (G), wherein the system (1) comprises a wire (10) having a proximal end (114, 121) and a distal end (112) as well as lumen (115) extending between these ends, wherein the system is characterized in that a matrix (13) for release of the agent is provided within the lumen (115), wherein the matrix (13) extends over at least part of the length of the wire (10). Thereby an oxygenation system for cerebral vessels can be provided.

摘要翻译： 本发明涉及一种用于将药剂引入血管（G）的系统，其中所述系统（1）还包括具有近端（114,121）和远端（112）的电线（10） 作为在这些端部之间延伸的管腔（115），其中该系统的特征在于，用于释放药剂的基质（13）设置在管腔（115）内，其中基质（13）延伸至长度的至少一部分 的线（10）。 从而可以提供用于脑血管的氧合系统。

公开(公告)号：US20080294086A1

公开(公告)日：2008-11-27

申请号：US12008130

申请日：2008-01-09

申请人： Christoph Hehrlein ,  Michael Braun ,  John S. Geis ,  Todd Davenport

发明人： Christoph Hehrlein ,  Michael Braun ,  John S. Geis ,  Todd Davenport

IPC分类号： A61M5/00 ,  A61N1/30 ,  A61M25/00

CPC分类号： A61L27/56 ,  A61L29/146 ,  A61L31/146

摘要： A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.

摘要翻译： 一种系统，包括：中空管，其具有远端，近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的富含气体的全氟化碳溶液; 其中所述多孔膜的孔隙率在0.001-200微米的范围内，以便：（i）富气体全氟化碳溶液有效地并入多孔膜中; 和（ii）当多孔膜位于血液中时，富含气体的全氟化碳溶液以足够小的聚集体从多孔膜中洗脱出来，以防止在血液中产生栓塞，同时溶解富含气体的全氟化碳溶液 根据血液的温度和血液动力学，血液在几分钟到几个小时之间变化。

公开(公告)号：US08333783B2

公开(公告)日：2012-12-18

申请号：US12024974

申请日：2008-02-01

申请人： Michael Braun ,  John S. Geis

发明人： Michael Braun ,  John S. Geis

IPC分类号： A61M29/00

CPC分类号： A61M29/02 ,  A61M25/0054 ,  A61M25/007 ,  A61M25/01 ,  A61M25/0169 ,  A61M25/04 ,  A61M2025/0183

摘要： A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas for vessel occlusion provided over the length of the catheter. The device further includes an elongate stretching member insertable longitudinally through the lumen of the catheter, the elongate stretching member being configured for stretching at least a portion of the catheter and causing the first and second expandable areas to transition from an expanded state to a collapsed state, and wherein the elongate stretching member is retracted proximally relative to the catheter causes the first and second expandable areas to transition from the collapsed state to a radially, or laterally expanded state.

公开(公告)号：US20100010308A1

公开(公告)日：2010-01-14

申请号：US11990567

申请日：2005-08-17

申请人： Michael Braun ,  John S. Geis

发明人： Michael Braun ,  John S. Geis

IPC分类号： A61B1/00 ,  A61B1/12

CPC分类号： A61B1/00142 ,  A61B1/00091 ,  A61B1/00101 ,  A61B1/012

摘要： The invention relates to a hygiene protection for endoscopes having at least one working channel (14), wherein the hygiene protection (2) comprises on its distal end a cap (15) with a working channel tube (17) arranged thereon and a protective sheath (21) connected to the cap (15). The hygiene protection is characterized in that the working channel tube (17) is arranged at the cap (15) with a distance to the circumference of the cap (15). Furthermore an endoscope (1) and a method for applying a hygiene protection (2) onto an endoscope (1) are described.

摘要翻译： 本发明涉及一种具有至少一个工作通道（14）的内窥镜的卫生保护装置，其中卫生保护装置（2）在其远端上包括盖子（15），其上安置有工作通道管（17）和保护套 （21）连接到盖（15）。 卫生保护的特征在于，工作通道管（17）布置在与盖（15）的圆周有距离的帽（15）处。 此外，还描述了内窥镜（1）和用于将卫生保护（2）施加到内窥镜（1）上的方法。

公开(公告)号：US06979321B2

公开(公告)日：2005-12-27

申请号：US10181741

申请日：2001-07-11

申请人： John S. Geis ,  Michael Braun

发明人： John S. Geis ,  Michael Braun

IPC分类号： A61B17/00 ,  A61B17/34 ,  A61M25/00 ,  A61M37/00 ,  A61M5/00 ,  A61M5/178 ,  A61M29/00

CPC分类号： A61M37/00 ,  A61B17/3478 ,  A61B2017/00247 ,  A61B2017/00986 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61M25/0068 ,  A61M25/0074 ,  A61M2025/0079 ,  A61M2210/125

摘要： An apparatus for inserting particles (P) into a tissue (G), in particular a muscle tissue, wherein the apparatus (10) essentially represents a tubular body (7) with one closed end and comprises at least one sleeve (8), at least one positioning element (1), at least one outlet area (2), which extends over the entire circumference of the tubular body (7), at least one thrust means (4) for the particles (P), as well as an actuating device for the outlet area (2), and wherein the outlet area (2) is formed by a plurality of flexible elements (6), which are at least attached to the sleeve (8), which butts against the outlet area (2) in the axial direction, or the positioning element (1) in such a way, that in a tense condition the diameter of the outlet area (2) is larger than the diameter of the sleeve (8), and openings are present between the elements (6).

摘要翻译： 一种用于将颗粒（P）插入组织（G），特别是肌肉组织中的装置，其中装置（10）基本上表示具有一个封闭端的管状体（7），并且包括至少一个套筒（8） 至少一个定位元件（1），至少一个在管体（7）的整个圆周上延伸的出口区域（2），至少一个用于颗粒（P）的推力装置（4），以及 用于出口区域（2）的致动装置，并且其中出口区域（2）由多个柔性元件（6）形成，所述多个柔性元件（6）至少附接到套筒（8），所述多个柔性元件（6）抵靠出口区域 ）或定位元件（1），使得在紧张状态下，出口区域（2）的直径大于套筒（8）的直径，并且开口存在于 元素（6）。