公开(公告)号：US08333783B2

公开(公告)日：2012-12-18

申请号：US12024974

申请日：2008-02-01

申请人： Michael Braun ,  John S. Geis

发明人： Michael Braun ,  John S. Geis

IPC分类号： A61M29/00

CPC分类号： A61M29/02 ,  A61M25/0054 ,  A61M25/007 ,  A61M25/01 ,  A61M25/0169 ,  A61M25/04 ,  A61M2025/0183

摘要： A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas for vessel occlusion provided over the length of the catheter. The device further includes an elongate stretching member insertable longitudinally through the lumen of the catheter, the elongate stretching member being configured for stretching at least a portion of the catheter and causing the first and second expandable areas to transition from an expanded state to a collapsed state, and wherein the elongate stretching member is retracted proximally relative to the catheter causes the first and second expandable areas to transition from the collapsed state to a radially, or laterally expanded state.

公开(公告)号：US20100010308A1

公开(公告)日：2010-01-14

申请号：US11990567

申请日：2005-08-17

申请人： Michael Braun ,  John S. Geis

发明人： Michael Braun ,  John S. Geis

IPC分类号： A61B1/00 ,  A61B1/12

CPC分类号： A61B1/00142 ,  A61B1/00091 ,  A61B1/00101 ,  A61B1/012

摘要： The invention relates to a hygiene protection for endoscopes having at least one working channel (14), wherein the hygiene protection (2) comprises on its distal end a cap (15) with a working channel tube (17) arranged thereon and a protective sheath (21) connected to the cap (15). The hygiene protection is characterized in that the working channel tube (17) is arranged at the cap (15) with a distance to the circumference of the cap (15). Furthermore an endoscope (1) and a method for applying a hygiene protection (2) onto an endoscope (1) are described.

摘要翻译： 本发明涉及一种具有至少一个工作通道（14）的内窥镜的卫生保护装置，其中卫生保护装置（2）在其远端上包括盖子（15），其上安置有工作通道管（17）和保护套 （21）连接到盖（15）。 卫生保护的特征在于，工作通道管（17）布置在与盖（15）的圆周有距离的帽（15）处。 此外，还描述了内窥镜（1）和用于将卫生保护（2）施加到内窥镜（1）上的方法。

公开(公告)号：US06979321B2

公开(公告)日：2005-12-27

申请号：US10181741

申请日：2001-07-11

申请人： John S. Geis ,  Michael Braun

发明人： John S. Geis ,  Michael Braun

IPC分类号： A61B17/00 ,  A61B17/34 ,  A61M25/00 ,  A61M37/00 ,  A61M5/00 ,  A61M5/178 ,  A61M29/00

CPC分类号： A61M37/00 ,  A61B17/3478 ,  A61B2017/00247 ,  A61B2017/00986 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61M25/0068 ,  A61M25/0074 ,  A61M2025/0079 ,  A61M2210/125

摘要： An apparatus for inserting particles (P) into a tissue (G), in particular a muscle tissue, wherein the apparatus (10) essentially represents a tubular body (7) with one closed end and comprises at least one sleeve (8), at least one positioning element (1), at least one outlet area (2), which extends over the entire circumference of the tubular body (7), at least one thrust means (4) for the particles (P), as well as an actuating device for the outlet area (2), and wherein the outlet area (2) is formed by a plurality of flexible elements (6), which are at least attached to the sleeve (8), which butts against the outlet area (2) in the axial direction, or the positioning element (1) in such a way, that in a tense condition the diameter of the outlet area (2) is larger than the diameter of the sleeve (8), and openings are present between the elements (6).

摘要翻译： 一种用于将颗粒（P）插入组织（G），特别是肌肉组织中的装置，其中装置（10）基本上表示具有一个封闭端的管状体（7），并且包括至少一个套筒（8） 至少一个定位元件（1），至少一个在管体（7）的整个圆周上延伸的出口区域（2），至少一个用于颗粒（P）的推力装置（4），以及 用于出口区域（2）的致动装置，并且其中出口区域（2）由多个柔性元件（6）形成，所述多个柔性元件（6）至少附接到套筒（8），所述多个柔性元件（6）抵靠出口区域 ）或定位元件（1），使得在紧张状态下，出口区域（2）的直径大于套筒（8）的直径，并且开口存在于 元素（6）。

公开(公告)号：US20140051929A1

公开(公告)日：2014-02-20

申请号：US13936087

申请日：2013-07-05

申请人： Michael Braun ,  John S. Geis

发明人： Michael Braun ,  John S. Geis

IPC分类号： A61B1/00

CPC分类号： A61B1/00142 ,  A61B1/00091 ,  A61B1/00101 ,  A61B1/012

摘要： The invention relates to a hygiene protection for endoscopes having at least one working channel (14), wherein the hygiene protection (2) comprises on its distal end a cap (15) with a working channel tube (17) arranged thereon and a protective sheath (21) connected to the cap (15). The hygiene protection is characterized in that the working channel tube (17) is arranged at the cap (15) with a distance to the circumference of the cap (15). Furthermore an endoscope (1) and a method for applying a hygiene protection (2) onto an endoscope (1) are described.

摘要翻译： 本发明涉及一种具有至少一个工作通道（14）的内窥镜的卫生保护装置，其中卫生保护装置（2）在其远端上包括盖子（15），其上安置有工作通道管（17）和保护套 （21）连接到盖（15）。 卫生保护的特征在于，工作通道管（17）布置在与盖（15）的圆周有距离的帽（15）处。 此外，还描述了内窥镜（1）和用于将卫生保护（2）施加到内窥镜（1）上的方法。

公开(公告)号：US08574258B2

公开(公告)日：2013-11-05

申请号：US12936666

申请日：2009-04-08

申请人： Michael Braun ,  John S. Geis ,  Brian M. Strauss ,  Jay A. Lenker

发明人： Michael Braun ,  John S. Geis ,  Brian M. Strauss ,  Jay A. Lenker

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/1204 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12172 ,  A61B2017/0042 ,  A61B2017/00862 ,  A61B2017/00867 ,  A61B2017/00986 ,  A61B2017/00995 ,  A61B2017/12127 ,  A61B2017/22038 ,  A61B2217/005

摘要： A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas provided over the length of the catheter. The device includes a first elongate member insertable longitudinally through the lumen of the catheter, the first elongate member being configured for stretching at least a portion of the catheter and causing one of the first and second expandable areas to transition from an expanded state to a collapsed state. The device further includes a second elongate member insertable longitudinally through the lumen of the catheter, the second elongate member being configured for stretching at least a portion of the catheter and causing the other of the first and second expandable areas to transition from an expanded state to a collapsed state.

摘要翻译： 用于在颈动脉血管治疗期间保护脑血管或脑组织的装置包括具有远侧部分，近端部分和在其间延伸的内腔的导管，该导管包括设置在导管长度上的第一和第二可扩张区域。 所述装置包括纵向通过所述导管的内腔插入的第一细长构件，所述第一细长构件构造成用于拉伸所述导管的至少一部分，并且使所述第一和第二可膨胀区域中的一个从膨胀状态转变为折叠状态 州。 所述装置还包括纵向延伸穿过所述导管的内腔的第二细长构件，所述第二细长构件被构造成用于拉伸所述导管的至少一部分并使所述第一和第二可扩张区域中的另一个从扩张状态转变为 崩溃状态

公开(公告)号：US08142412B2

公开(公告)日：2012-03-27

申请号：US12008130

申请日：2008-01-09

申请人： Christoph Hehrlein ,  Michael Braun ,  John S. Geis ,  Todd Davenport

发明人： Christoph Hehrlein ,  Michael Braun ,  John S. Geis ,  Todd Davenport

IPC分类号： A61M31/00

CPC分类号： A61L27/56 ,  A61L29/146 ,  A61L31/146

摘要： A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.

摘要翻译： 一种系统，包括：中空管，其具有远端，近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的富含气体的全氟化碳溶液; 其中所述多孔膜的孔隙率在0.001-200微米的范围内，以便：（i）富气体全氟化碳溶液有效地并入多孔膜中; 和（ii）当多孔膜位于血液中时，富含气体的全氟化碳溶液以足够小的聚集体从多孔膜中洗脱出来，以防止在血液中产生栓塞，同时溶解富含气体的全氟化碳溶液 根据血液的温度和血液动力学，血液在几分钟到几个小时之间变化。

公开(公告)号：US20120022572A1

公开(公告)日：2012-01-26

申请号：US12936666

申请日：2009-04-08

申请人： Michael Braun ,  John S. Geis ,  Brian M. Strauss ,  Jay A. Lenker

发明人： Michael Braun ,  John S. Geis ,  Brian M. Strauss ,  Jay A. Lenker

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/1204 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12172 ,  A61B2017/0042 ,  A61B2017/00862 ,  A61B2017/00867 ,  A61B2017/00986 ,  A61B2017/00995 ,  A61B2017/12127 ,  A61B2017/22038 ,  A61B2217/005

摘要： A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas provided over the length of the catheter. The device includes a first elongate member insertable longitudinally through the lumen of the catheter, the first elongate member being configured for stretching at least a portion of the catheter and causing one of the first and second expandable areas to transition from an expanded state to a collapsed state. The device further includes a second elongate member insertable longitudinally through the lumen of the catheter, the second elongate member being configured for stretching at least a portion of the catheter and causing the other of the first and second expandable areas to transition from an expanded state to a collapsed state.

摘要翻译： 用于在颈动脉血管治疗期间保护脑血管或脑组织的装置包括具有远侧部分，近端部分和在其间延伸的内腔的导管，该导管包括设置在导管长度上的第一和第二可扩张区域。 所述装置包括纵向通过所述导管的内腔插入的第一细长构件，所述第一细长构件构造成用于拉伸所述导管的至少一部分，并且使所述第一和第二可膨胀区域中的一个从膨胀状态转变为折叠状态 州。 所述装置还包括纵向延伸穿过所述导管的内腔的第二细长构件，所述第二细长构件被构造成用于拉伸所述导管的至少一部分并使所述第一和第二可扩张区域中的另一个从扩张状态转变为 崩溃状态

公开(公告)号：US20090326508A1

公开(公告)日：2009-12-31

申请号：US12472759

申请日：2009-05-27

申请人： Michael Braun ,  John S. Geis ,  Todd F. Davenport

发明人： Michael Braun ,  John S. Geis ,  Todd F. Davenport

IPC分类号： A61M25/10 ,  A61M25/09

CPC分类号： A61M25/0009 ,  A61M25/104 ,  A61M2025/0057 ,  A61M2025/105

摘要： A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a pharmacological agent incorporated in the porous membrane; wherein the porous membrane has a porosity such that: (i) the pharmacological agent is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the pharmacological agent elutes out of the porous membrane at a rate which matches the desired rate of dosage for the pharmacological agent.

摘要翻译： 一种系统，包括：中空管，其具有远端，近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的药剂; 其中所述多孔膜具有孔隙率，使得：（i）所述药理学试剂有效地并入所述多孔膜中; 和（ii）当多孔膜位于血液中时，药理学试剂以与药物剂的所需剂量速率相匹配的速率从多孔膜中洗出。

公开(公告)号：US20080200946A1

公开(公告)日：2008-08-21

申请号：US12024974

申请日：2008-02-01

申请人： Michael Braun ,  John S. Geis

发明人： Michael Braun ,  John S. Geis

IPC分类号： A61M29/00

CPC分类号： A61M29/02 ,  A61M25/0054 ,  A61M25/007 ,  A61M25/01 ,  A61M25/0169 ,  A61M25/04 ,  A61M2025/0183

摘要： A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas for vessel occlusion provided over the length of the catheter. The device further includes an elongate stretching member insertable longitudinally through the lumen of the catheter, the elongate stretching member being configured for stretching at least a portion of the catheter and causing the first and second expandable areas to transition from an expanded state to a collapsed state, and wherein the elongate stretching member is retracted proximally relative to the catheter causes the first and second expandable areas to transition from the collapsed state to a radially, or laterally expanded state.

摘要翻译： 用于在颈动脉血管治疗期间保护脑血管或脑组织的装置包括具有远侧部分，近端部分和在其间延伸的内腔的导管，该导管包括在导管的长度上提供的用于血管闭塞的第一和第二可扩张区域 。 所述装置还包括纵向延伸通过所述导管的内腔的细长拉伸构件，所述细长拉伸构件被构造成用于拉伸所述导管的至少一部分并使所述第一和第二可扩张区域从膨胀状态转变为折叠状态 并且其中所述细长拉伸构件相对于所述导管向近侧缩回，使得所述第一和第二可膨胀区域从所述收缩状态转变到径向或横向膨胀状态。

公开(公告)号：US20090054878A1

公开(公告)日：2009-02-26

申请号：US11895249

申请日：2007-08-23

申请人： John S. Geis ,  Michael Braun

发明人： John S. Geis ,  Michael Braun

IPC分类号： A61B17/00

CPC分类号： A61B50/30

摘要： The invention relates to a device for introducing a medical instrument into a closed container (2). The device is characterized in that it has a penetration means (11) for penetration of a container wall and a guiding unit (12) is adjacent to the penetration means (11), wherein the penetration means (11) and the guiding unit (12) have a common passage (10) for the introduction of a medical instrument (3) and the passage (10) has at least temporarily a narrowing.

摘要翻译： 本发明涉及一种用于将医疗器械引入密闭容器（2）中的装置。 该装置的特征在于其具有用于穿透容器壁的穿透装置（11），并且引导单元（12）邻近穿透装置（11），其中穿透装置（11）和引导单元（12） ）具有用于引入医疗器械（3）的共同通道（10），并且通道（10）至少暂时变窄。