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公开(公告)号：US20110198244A1
公开(公告)日：2011-08-18
申请号：US13026841
申请日：2011-02-14
申请人： Michael C. Murad , Mark Van Nest , Jackie Lau
发明人： Michael C. Murad , Mark Van Nest , Jackie Lau
IPC分类号： B65D81/24
CPC分类号： A61F2/0095 , A61F2/24
摘要： Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a sterile jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. A delivery handle on the end of a shaft couples with the valve holder while the packaging sleeve engages the jar to prevent rotation. The assembly of the packaging sleeve, valve, and holder can then easily be removed from the jar.
摘要翻译： 用于假体心脏瓣膜的包装，包括用于将心脏瓣膜牢固地保持在无菌罐内并有助于从其中取出的组件。 组件包括紧密地配合在罐内的包装套筒，并具有用于固定阀座的夹子结构。 轴的端部上的输送手柄与阀保持器相耦合，同时包装套筒与罐接合以防止旋转。 然后可以容易地从罐中移除包装套筒，阀和保持器的组件。
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公开(公告)号：US08839957B2
公开(公告)日：2014-09-23
申请号：US13026841
申请日：2011-02-14
申请人： Michael C. Murad , Mark Van Nest , Jackie Lau
发明人： Michael C. Murad , Mark Van Nest , Jackie Lau
CPC分类号： A61F2/0095 , A61F2/24
摘要： Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a sterile jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. A delivery handle on the end of a shaft couples with the valve holder while the packaging sleeve engages the jar to prevent rotation. The assembly of the packaging sleeve, valve, and holder can then easily be removed from the jar.
摘要翻译： 用于假体心脏瓣膜的包装，包括用于将心脏瓣膜牢固地保持在无菌罐内并有助于从其中取出的组件。 组件包括紧密地配合在罐内的包装套筒，并具有用于固定阀座的夹子结构。 轴的端部上的输送手柄与阀保持器相耦合，同时包装套筒与罐接合以防止旋转。 然后可以容易地从罐中移除包装套筒，阀和保持器的组件。
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公开(公告)号：US20160067042A1
公开(公告)日：2016-03-10
申请号：US14850829
申请日：2015-09-10
申请人： Michael C. Murad , Hilda Z. Fann , Mark Van Nest , John X. Wang
发明人： Michael C. Murad , Hilda Z. Fann , Mark Van Nest , John X. Wang
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/06 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2230/0076 , A61F2230/0095 , A61F2240/001 , A61F2250/006
摘要： A valved conduit including a bioprosthetic aortic heart valve connected to a tubular conduit graft forming an ascending aorta. The conduit graft may attach to the heart valve in a manner that facilitates a redo operation in which the valve is replaced with another valve. A sewing ring may be pre-attached to the inflow end of the graft, and then the valve connected to a delivery holder advanced into the graft and secured to the sewing ring. Dry bioprosthetic valves coupled with conduit grafts sealed with a bioresorbable medium can be stored with the delivery holder.
摘要翻译： 一个带阀的导管，其包括连接到形成升主动脉的管状导管移植物的生物假体主动脉瓣心脏瓣膜。 导管移植物可以以促进重新操作的方式附接到心脏瓣膜，其中阀被另一个阀替代。 缝合环可以预先附接到移植物的流入端，然后连接到输送保持器的瓣膜进入移植物并固定到缝合环上。 与生物可吸收介质密封的导管移植物结合的干生物假肢瓣膜可以与输送支架一起储存。
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公开(公告)号：US09078750B2
公开(公告)日：2015-07-14
申请号：US13306212
申请日：2011-11-29
CPC分类号： A61F2/2427 , A61B2017/00243 , A61B2017/0496 , A61F2/24 , A61F2/2409 , A61F2/2454 , A61F2230/0071
摘要： A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation. The holder may be shaped as a ring with an open inner diameter for enhanced access to the commissure posts and leaflets.
摘要翻译： 用于假体二尖瓣心脏瓣膜的保持器，其附接到瓣膜的流入端，并且包括将心脏瓣膜连接柱向内弯曲的简单张紧机构，以帮助防止缝合线循环。 张紧机构可以包括保持器的相对可移动的环或具有张量或可旋转旋钮的大体上一体的保持器。 连接缝合线通过保持器内部的通道，沿着流出方向沿阀门连接柱移动，出现在后端，并在阀的流出侧相互交叉。 手柄位于支架上偏心，通过中央窗口增加对心脏瓣膜的可视化和访问。 保持器由非金属材料构成，以避免干扰成像装置，并且手柄符合人体工程学地弯曲和成形以便于操纵。 保持器可以形成为具有开口内径的环，以增强对连合柱和传单的接近。
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公开(公告)号：US20120290079A1
公开(公告)日：2012-11-15
申请号：US13469975
申请日：2012-05-11
CPC分类号： A61F2/2427 , A61F2/0095 , A61F2/2409 , A61F2/2412 , A61F2220/0075 , A61F2230/0006 , A61F2250/001
摘要： An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. The holder has a safety mechanism that prevents valve delivery before the rod is deployed. One embodiment automatically deploys the rod upon opening a storage jar. One embodiment permits a delivery handle to directly deploy the rod, while another uses a separate worm screw and coupling. A holder clip that attaches to a packaging sleeve may be formed of flexible members meshed together from which the heart valve and holder are easily pulled free to eliminate a step of decoupling the clip from the sleeve.
摘要翻译： 一种用于组织型假体二尖瓣心脏瓣膜的改进的保持器和储存系统，其限制瓣膜的连合柱并防止缝线循环。 杆相对于保持器可轴向移动，连接缝合线的长度在连接柱末端之间延伸以形成帐篷并向内弯曲顶端，从而有助于防止任何一组预先植入的缝线围绕前端尖端环绕， 输送阀门。 支架具有安全机构，可在杆部署之前防止阀门传递。 一个实施例在打开储存罐时自动展开杆。 一个实施例允许递送手柄直接展开杆，而另一个使用单独的蜗杆和联接。 附接到包装套筒的保持夹可以由啮合在一起的柔性构件形成，心脏瓣膜和保持器从该夹子容易地拉开，以消除将夹子与套筒分离的步骤。
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公开(公告)号：US08968394B2
公开(公告)日：2015-03-03
申请号：US13469975
申请日：2012-05-11
CPC分类号： A61F2/2427 , A61F2/0095 , A61F2/2409 , A61F2/2412 , A61F2220/0075 , A61F2230/0006 , A61F2250/001
摘要： An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. The holder has a safety mechanism that prevents valve delivery before the rod is deployed. One embodiment automatically deploys the rod upon opening a storage jar. One embodiment permits a delivery handle to directly deploy the rod, while another uses a separate worm screw and coupling. A holder clip that attaches to a packaging sleeve may be formed of flexible members meshed together from which the heart valve and holder are easily pulled free to eliminate a step of decoupling the clip from the sleeve.
摘要翻译： 一种用于组织型假体二尖瓣心脏瓣膜的改进的保持器和储存系统，其限制瓣膜的连合柱并防止缝线循环。 杆相对于保持器可轴向移动，连接缝合线的长度在连接柱末端之间延伸以形成帐篷并向内弯曲顶端，从而有助于防止任何一组预先植入的缝线围绕前端尖端环绕， 输送阀门。 支架具有安全机构，可在杆部署之前防止阀门传递。 一个实施例在打开储存罐时自动展开杆。 一个实施例允许递送手柄直接展开杆，而另一个使用单独的蜗杆和联接。 附接到包装套筒的保持夹可以由啮合在一起的柔性构件形成，心脏瓣膜和保持器从该夹子容易地拉开，以消除将夹子与套筒分离的步骤。
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公开(公告)号：US20120136434A1
公开(公告)日：2012-05-31
申请号：US13306212
申请日：2011-11-29
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61B2017/00243 , A61B2017/0496 , A61F2/24 , A61F2/2409 , A61F2/2454 , A61F2230/0071
摘要： A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation. The holder may be shaped as a ring with an open inner diameter for enhanced access to the commissure posts and leaflets.
摘要翻译： 用于假体二尖瓣心脏瓣膜的保持器，其附接到瓣膜的流入端，并且包括将心脏瓣膜连接柱向内弯曲的简单张紧机构，以帮助防止缝合线循环。 张紧机构可以包括保持器的相对可移动的环或具有张量或可旋转的旋钮的大体上一体的保持器。 连接缝合线通过保持器内部的通道，沿着流出方向沿阀门连接柱移动，出现在后端，并在阀的流出侧相互交叉。 手柄位于支架上偏心，以通过中心窗口增加对心脏瓣膜的可视化和访问。 保持器由非金属材料构成，以避免干扰成像装置，并且手柄符合人体工程学地弯曲和成形以便于操纵。 保持器可以被成形为具有开口内径的环，以增强对连合柱和传单的接近。
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