摘要:
The present invention describes a catheter suitable for introduction into a tubular tissue for dissolving blockages in such tissue. The catheter is particularly useful for removing thrombi within blood vessels. In accordance with the preferred embodiments, a combination of vibrating motion and injection of a lysing agent is utilized to break up blockages in vessels. The vessels may be veins, arteries, ducts, intestines, or any lumen within the body that may become blocked from the material that flows through it. As a particular example, dissolution of vascular thrombi facilitated by advancing a catheter through the occluded vessel, the catheter causing a vibrating, stirring action in and around the thrombus usually in combination with the dispensing of a thrombolytic agent such as urokinase into the thrombus. The catheter has an inflatable or expandable member near the distal tip which, when inflated or expanded, prevents the passage of dislodged thrombus around the catheter. The dislodged portions of thrombus are directed through a perfusion channel in the catheter, where they are removed by filtration means housed within the perfusion channel before the blood exists the tip of the catheter. Catheters that allow both low frequency (1-100 Hz) vibratory motion and delivery of such agents to a blockage and a method for using such catheters are disclosed.
摘要:
The present invention describes a catheter suitable for introduction into a tubular tissue for dissolving blockages in such tissue. The catheter is particularly useful for removing thrombi within blood vessels. In accordance with the preferred embodiments, a combination of vibrating motion and injection of a lysing agent is utilized to break up blockages in vessels. The vessels may be veins, arteries, ducts, intestines, or any lumen within the body that may become blocked from the material that flows through it. As a particular example, dissolution of vascular thrombi facilitated by advancing a catheter through the occluded vessel, the catheter causing a vibrating, stirring action in and around the thrombus usually in combination with the dispensing of a thrombolytic agent such as urokinase into the thrombus. The catheter has an inflatable or expandable member near the distal tip which, when inflated or expanded, prevents the passage of dislodged thrombus around the catheter. The dislodged portions of thrombus are directed through a perfusion channel in the catheter, where they are removed by filtration means housed within the perfusion channel before the blood exists the tip of the catheter. Catheters that allow both low frequency (1-100 Hz) vibratory motion and delivery of such agents to a blockage and a method for using such catheters are disclosed.
摘要:
A catheter suitable for dissolving blockages in tubular tissue provides a combination of low frequency (1–100 Hz) vibratory motion and injection of a lysing agent. The tubular tissue may be veins, arteries, ducts, intestines, or any other blocked body lumen. For vascular thrombi, the catheter may induce a vibrating, stirring action in and around the thrombus in combination with dispensing of a thrombolytic agent, such as urokinase, into the thrombus. An inflatable or expandable member may be provided near a distal tip of the catheter to prevent release of dislodged thrombus.
摘要:
A method of forming an aggregate. The method comprising forming a green pellet including waste glass and additive(s). The unfired pellets are coated with a refractory material and sintered such that some of the additive/additives breaks down to generate gas which is at least partially retained in the microstructure of the mixture to form pores, the additive/additives so being that upon heating the additive/additives and glass combine to produce glass ceramics.
摘要:
Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed.
摘要:
A method of determining the density of an underground formation surrounding a borehole from measurement of gamma rays arising from irradiation of the formation by a nuclear source in a tool body located in the borehole, and measurement of gamma-ray flux in the tool body at two different detector spacings from the source, the method comprising determining a substantially straight-line relationship between gamma-ray flux measurements at each different spacing with respect to the density of the formation for a tool body with no standoff; determining a relationship defining the deviation with respect to tool standoff of the density determined from the measured gamma-ray flux measurements at the two different detector spacings from the density calculated from the straight line relationships; and for a given pair of gamma-ray flux measurements at the different detector spacings, determining the intersection of the relationship defining the deviation with the straight line relationship so as to indicate the density of the formation surrounding the bore-hole; wherein the source is a neutron source and the gamma rays measured in the too! body are neutron-induced gamma rays resulting from neutron irradiation of the formation.
摘要:
A method of changing from a first gear position to a second gear position of a transmission arrangement is disclosed. The arrangement includes a rotatable transmission member, a hydrostatic continuously variable transmission coupled to the transmission member and operable to rotate the transmission member at a first speed, a controller configured to control operation of the hydrostatic continuously variable transmission, and a gear apparatus coupled to the transmission member and configured to be shiftable between at least the first gear position and the second gear position. The method includes controlling the hydrostatic continuously variable transmission, using the controller, to rotate the transmission member at the first speed, and shifting the gear apparatus from the first gear position to the second gear position while the transmission member is rotating at, or converging with, the first speed.
摘要:
A primary or secondary game for a gaming device. In one embodiment, the player is provided up to three picks, i.e., picks three contestants. The first two contestants both form potential award offers. The game then provides the greater of the two potential award offers to the player as an initial offer. This initial sequence alternatives includes more than two picks, contestants and potential offers. The offer acceptance feature arises after the initial offer. The player must decide whether to keep the initial offer or forego that offer for a final offer. If the player keeps the offer the game provides that initial offer to the player and ends if the player rejects that initial offer, the game proceeds to build a third and final offer, which is then provided to the player automatically.
摘要:
A package of compressed blowing insulation includes a body of compressed blowing insulation, a bag encapsulating the body of compressed blowing insulation and a slit extending through the package to define a partially divided package.
摘要:
A method of detecting a target in a scene comprises the steps of (a) obtaining a first data set of data elements which correspond to returns from different parts of the scene; and (b) determining a detection threshold for a part of the scene by reference to data elements corresponding to returns to neighbouring parts of the scene; characterized in that (i) the method further comprises the steps of (c) obtaining a second data set of data elements which correspond only to clutter returns from different parts of the scene; and (d) identifying clutter returns in the first data set by comparing the first and second data sets; and (ii) in step (b), data elements identified in step (d) as corresponding to clutter returns are discounted in determining the detection threshold. The method provides for improved target detection the presence of clutter.