-
公开(公告)号：US5057536A
公开(公告)日：1991-10-15
申请号：US351391
申请日：1989-05-09
申请人： Michael J. Dawson , David Noble , Gordon C. Lawrence , Richard A. Fletton , Stephen J. Lane , Michael V. J. Ramsay , Oswy Z. Pereira , Derek R. Sutherland , Edward P. Tiley
发明人： Michael J. Dawson , David Noble , Gordon C. Lawrence , Richard A. Fletton , Stephen J. Lane , Michael V. J. Ramsay , Oswy Z. Pereira , Derek R. Sutherland , Edward P. Tiley
IPC分类号： C12P17/18 , A01N43/90 , A61K31/335 , A61K31/365 , A61P33/10 , C07D493/22 , C07H19/01 , C12R1/465 , C12R1/585 , C12R1/59 , C12R1/645
摘要： Compounds of formula (1) ##STR1## and salts thereof, wherein R.sup.1 represents a methyl, ethyl or isopropyl group;Y.sup.1 is --CH.sub.2 --, Y.sup.2 is --CH-- and X represents ##STR2## where R.sup.2 represents a hydrogen atom or a group OR.sup.8 (where OR.sup.8 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 represents a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent >C.dbd.O, >C.dbd.CH.sub.2 or >C.dbd.NOR.sup.9 (where R.sup.9 represents a hydrogen atom, a C.sub.1-8 alkyl group or a C.sub.3-8 alkenyl group) and the group >C.dbd.NOR.sup.9 is in the E configuration] or --Y.sup.1 --X--Y.sup.2 -- represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--;R.sup.4 represents a group OR.sup.8 as defined above and R.sup.5 represents a hydrogen atom, or R.sup.4 and R.sup.5 together with the carbon atom to which they are attached represent >C.dbd.O or >C.dbd.NOR.sup.9a (where R.sup.9a is as defined above for R.sup.9);R.sup.6 represents a hydrogen atom and R represents --CH.sub.2 OH, --CHO, --CO.sub.2 H or a carboxylic acid ester or amide group; or R.sup.6 represents a hydroxyl group and R represents a methyl group; andR.sup.7 represents a hydrogen atom or when R represents a group --CH.sub.2 OH then R.sup.7 may also represent a hydroxyl group.The compounds may be used to control nematode, acarine, insect or other pests.
-
公开(公告)号：US5116968A
公开(公告)日：1992-05-26
申请号：US630437
申请日：1990-12-20
申请人： Gordon C. Lawrence , Michael J. Dawson , David Noble , Michael V. J. Ramsay , Richard Bell , Derek R. Sutherland , Edward P. Tiley
发明人： Gordon C. Lawrence , Michael J. Dawson , David Noble , Michael V. J. Ramsay , Richard Bell , Derek R. Sutherland , Edward P. Tiley
IPC分类号： C12P19/62 , A01N43/90 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P33/00 , C07D493/22 , C07H17/08 , C07H19/01 , C12R1/465
摘要： Compounds of formula (1) ##STR1## wherein R represents a sugar residue or an acylated derivative thereof;R.sup.1 represents a methyl, ethyl or isopropyl group;Y.sup.1 is --CH.sub.2, Y.sup.2 is --CH-- and X represents ##STR2## [wherein R.sup.2 represents a hydrogen atom or a group OR.sup.6 (where OR.sup.6 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 represents a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent >C.dbd.0, >C.dbd.CH.sub.2 or >C.dbd.NOR.sup.7 (where R.sup.7 represents a hydrogen atom, a C.sub.1-8 alkyl group or a C.sub.3-8 alkenyl group) and the group >C.dbd.NOR.sup.7 is in the E configuration] or --Y.sup.1 --X--Y.sup.2 -- represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--; andR.sup.4 represents a group OR.sup.6 as defined above and R.sup.5 represents a hydrogen atom, or R.sup.4 and R.sup.5 together with the carbon atom to which the are attached represent >C.dbd.0 or >C.dbd.NOR.sup.8 (where R.sup.8 is as defined above for R.sup.7), and salts thereof. The compounds may be used to control nematode, acarine, insect or other pests.
-
公开(公告)号：US5108992A
公开(公告)日：1992-04-28
申请号：US630438
申请日：1990-12-20
IPC分类号： C07D493/22 , A01N43/90 , A61K31/365 , A61P33/00 , C07H19/01 , C12P17/18 , C12R1/465
摘要： Compounds of formula (1) ##STR1## and their salts, wherein R.sup.1 is a methyl, ethyl or isopropyl group each substituted by a hydroxyl group or R.sup.1 is a group --(CH.sub.2).sub.n R7 or a group --CH(CH.sub.3)R.sup.7 (where n is zero or 1 and R.sup.7 l is CHO or CO.sub.2 H);Y.sup.1 is --CH.sub.2 --, Y.sup.2 is --CH-- and X represents ##STR2## [where R.sup.2 is a hydrogen atom or a group OR.sup.8 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 is a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent >.dbd.O, >C.dbd.CH.sub.2 or >C.dbd.NOR.sup.9 (where R.sup.9 is a hydrogen atom or a C.sub.1-8 alkyl or C.sub.3-8 alkenyl group) and the group >C.dbd.NOR.sup.9 is in the E configuration] or --Y.sup.1 --X--Y.sup.2 -- represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--;R.sup.4 is a group OR.sup.8 as defined above and R.sup.5 is a hydrogen atom, or R.sup.4 and R.sup.5 together with the carbon atom to which they are attached represent >C.dbd.O or >C.dbd.NOR.sup.9a (where R.sup.9a is as defined above for R.sup.9); andR.sup.6 is a hydrogen atom or a hydroxyl group. The compounds may be used to control nematode, acarine, insect or other pests.
-
公开(公告)号：US5378617A
公开(公告)日：1995-01-03
申请号：US933578
申请日：1992-08-24
申请人： Martin Todd , Mark A. Haxell , Gordon C. Lawrence
发明人： Martin Todd , Mark A. Haxell , Gordon C. Lawrence
IPC分类号： A61K31/365 , A61P31/04 , C07D493/22 , C07H19/01 , C12P17/08 , C12P17/18 , C12P19/44 , C12R1/465 , C12N1/20
CPC分类号： C07H19/01 , C12P17/08 , C12P19/445 , C12R1/465
摘要： A process for the production of a compound of formula (I) ##STR1## which comprises cultivating a microorganism of the genus Streptomyces capable of producing the compound of formula (I) in the presence of one or more fatty acids and/or salts, esters and amides of these acids, whereby the compound of formula (I) is produced, and if desired isolating the said compound. The fatty acid increases the yield of the formula (I) compound and is preferably isobutyric or valeric acid.
摘要翻译： 一种制备式（I）化合物（I）的方法，其包括在一种或多种脂肪酸和/或其中存在下培养能够产生式（I）化合物的链霉菌属的微生物 盐，酯和酰胺，由此制备式（I）化合物，如果需要，分离所述化合物。 脂肪酸提高式（I）化合物的产率，优选为异丁酸或戊酸。
-
-
-
搜索结果
4 条记录 (耗时 0.038 秒)
