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公开(公告)号:US20120329720A1
公开(公告)日:2012-12-27
申请号:US13537273
申请日:2012-06-29
CPC分类号: C12N9/1205 , A61K38/00
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
摘要翻译: 本发明提供抗炎化合物,其药物组合物及其用于治疗炎症性疾病的方法。 本发明还提供鉴定抗炎化合物的方法和抑制细胞中NF-和κ-依赖性靶基因表达的方法。
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公开(公告)号:US08242240B2
公开(公告)日:2012-08-14
申请号:US12869962
申请日:2010-08-27
IPC分类号: C07K14/00
CPC分类号: C12N9/1205 , A61K38/00
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
摘要翻译: 本发明提供抗炎化合物,其药物组合物及其用于治疗炎症性疾病的方法。 本发明还提供鉴定抗炎化合物的方法和抑制细胞中NF-和κ-依赖性靶基因表达的方法。
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公开(公告)号:US20090286748A1
公开(公告)日:2009-11-19
申请号:US12421488
申请日:2009-04-09
CPC分类号: C12N9/1205 , A61K38/00
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
摘要翻译: 本发明提供抗炎化合物,其药物组合物及其用于治疗炎症性疾病的方法。 本发明还提供鉴定抗炎化合物的方法和抑制细胞中NF-κB依赖性靶基因表达的方法。
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公开(公告)号:US20110071092A1
公开(公告)日:2011-03-24
申请号:US12869962
申请日:2010-08-27
CPC分类号: C12N9/1205 , A61K38/00
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
摘要翻译: 本发明提供抗炎化合物,其药物组合物及其用于治疗炎症性疾病的方法。 本发明还提供鉴定抗炎化合物的方法和抑制细胞中NF-和κ-依赖性靶基因表达的方法。
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公开(公告)号:US07812118B2
公开(公告)日:2010-10-12
申请号:US12421488
申请日:2009-04-09
CPC分类号: C12N9/1205 , A61K38/00
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
摘要翻译: 本发明提供抗炎化合物,其药物组合物及其用于治疗炎症性疾病的方法。 本发明还提供鉴定抗炎化合物的方法和抑制细胞中NF-和κ-依赖性靶基因表达的方法。
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公开(公告)号:US07534858B2
公开(公告)日:2009-05-19
申请号:US11439528
申请日:2006-05-22
CPC分类号: C12N9/1205 , A61K38/00
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
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公开(公告)号:US07049395B2
公开(公告)日:2006-05-23
申请号:US09847946
申请日:2001-05-02
CPC分类号: C12N9/1205 , A61K38/00
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
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公开(公告)号:US20060293244A1
公开(公告)日:2006-12-28
申请号:US11439528
申请日:2006-05-22
申请人: Michael May , Sankar Ghosh , Mark Findeis , Kathryn Phillips , Gerhard Hannig
发明人: Michael May , Sankar Ghosh , Mark Findeis , Kathryn Phillips , Gerhard Hannig
CPC分类号: C12N9/1205 , A61K38/00
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
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公开(公告)号:US07872094B2
公开(公告)日:2011-01-18
申请号:US12424334
申请日:2009-04-15
申请人: Michael J. May , Sankar Ghosh
发明人: Michael J. May , Sankar Ghosh
CPC分类号: C07K14/4703 , A61K38/00 , C07K14/4747 , C12N9/1205
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
摘要翻译: 本发明提供抗炎化合物,其药物组合物及其用于治疗炎症性疾病的方法。 本发明还提供鉴定抗炎化合物的方法和抑制细胞中NF-和κ-依赖性靶基因表达的方法。
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公开(公告)号:US07538089B2
公开(公告)日:2009-05-26
申请号:US10979683
申请日:2004-11-01
申请人: Michael J. May , Sankar Ghosh
发明人: Michael J. May , Sankar Ghosh
CPC分类号: C07K14/4703 , A61K38/00 , C07K14/4747 , C12N9/1205
摘要: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
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