摘要:
Methods of isolating cellular products, such as pancreatic islets, may be used in diabetes research and therapeutic transplantation. The methods may involve providing a donor tissue having desired cells and undesired cells, perfusing the donor tissue with a perfusion solution, developing edema during perfusion of the donor tissue to form a swelled tissue, and separating the desired cells from undesired cellular material to obtain a cellular product. The methods may also include disrupting the tissue, and separating the desired cells from undesired cellular material to obtain the cellular product. The methods may result in an increased yield of cellular product that retains sufficient functional integrity to be useful as a transplantation resource.
摘要:
Disclosed is a cannula including a first circumferential portion, a second circumferential portion, and a seal with a first clamping surface. The first circumferential portion and the second circumferential portion are configured to mutually cooperate to support a circumference of vasculature, and form a second clamping surface. The first clamping surface and the second clamping surface are configured to cooperate to secure an end of the vasculature.
摘要:
The present invention is directed to methods and apparatus for improving error indication performance in systems employing low-density parity check (LDPC) codes. In one aspect, a method and apparatus for providing error indication based on full LDPC parity check re-encoding are provided. In an embodiment, an LDPC encoder is employed at the receiver to re-encode the parity bits. In another embodiment, the parity bits are re-encoded recursively based on information readily available at the decoder of the receiver. In another aspect, a method and apparatus for providing error indication based on partial LDPC parity check re-encoding are provided. In an embodiment, partial checksum information is determined based on the decoder output and used to provide error indication. In a further aspect, a hybrid CRC checking and LDPC parity check re-encoding approach is provided. This approach further enhances error indication performance by reducing the miss probability compared to pure LDPC parity check re-encoding.
摘要:
A method and an apparatus are provided for use in a user device for limiting the ability of the terminal of the user device to replay protected content. The low-level key that is used by the decryption component of the terminal to decrypt content is transient in that it expires if at least one predetermined expiration criteria is met. After they key has expired, it is no longer valid and thus cannot be used by the decryption component to decrypt protected content. Limiting the ability of the terminal to replay protected content is preferably accomplished in a way that does not affect the ability of the terminal to play and replay unprotected content.
摘要:
Methods for ex vivo perfusion of organs (and/or tissues) with a perfusate designed to condition the organ with the desired effect being that upon transplant, said organ, having been administered said perfusate, is less likely to experience delayed graft function, deleterious effects of ischemia/reperfusion injury, including inflammatory reactions, and/or other detrimental responses that can injure the organ or recipient including precipitating or enhancing an immunological reaction from the recipient with the potential of compromising the graft's and/or recipients short teen and/or long term health and proper functionality while monitoring, sustaining and/or restoring the viability of the organ and preserving the organ for storage and/or transport.
摘要:
Methods for assaying properties in tissues or organs of drugs and other chemical compounds and substances include ex vivo normothermic perfusion with a fluid containing a test substance to obtain data regarding the tissue or organ, the substance and/or an interaction of the substance and the tissue or organ. The data can be used as, for example, part of a submission to a government regulatory organization.
摘要:
Disclosed is a cannula including a first circumferential portion, a second circumferential portion, and a seal with a first clamping surface. The first circumferential portion and the second circumferential portion are configured to mutually cooperate to support a circumference of vasculature, and form a second clamping surface. The first clamping surface and the second clamping surface are configured to cooperate to secure an end of the vasculature.
摘要:
Properties such as toxicity of substances may be determined by assaying properties, fates and effects of substances in an ex vivo metabolically active human organ or tissue under normothermic perfusion with a fluid containing a test substance. The data can be used as, for example, part of a submission to a government regulatory organization. Preferred methods use perfused endocrine gland organs or tissues to evaluate hormone or other bodily chemical disruption caused by substances and pre-donation diseased or injured organs or tissues.
摘要:
A cannula includes a first circumferential portion, a second circumferential portion, and a seal with a first clamping surface. The first circumferential portion and the second circumferential portion are configured to mutually cooperate to support a circumference of vasculature, and form a second clamping surface. The first clamping surface and the second clamping surface are configured to cooperate to secure an end of the vasculature.