-
公开(公告)号:US20080171880A1
公开(公告)日:2008-07-17
申请号:US12049968
申请日:2008-03-17
IPC分类号: C07D241/10
CPC分类号: C07D241/26 , A61K31/4965 , A61K31/497 , C07D241/32 , C07D403/12 , C07D413/12 , C07D417/12 , C07D473/00 , C07D473/16
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
-
公开(公告)号:US20090018144A1
公开(公告)日:2009-01-15
申请号:US12171814
申请日:2008-07-11
IPC分类号: A61K31/497 , C07D403/12 , C07D241/28 , A61K31/4965 , C07K14/435 , A61P11/06
摘要: The present invention relates to compounds represented by formula (I): where the structural variables are as defined herein. The compounds are useful for promoting hydration of mucosal surfaces.
摘要翻译: 本发明涉及由式(I)表示的化合物:其中结构变量如本文所定义。 这些化合物可用于促进粘膜表面的水合。
-
公开(公告)号:US07064129B2
公开(公告)日:2006-06-20
申请号:US10920410
申请日:2004-08-18
IPC分类号: A61K31/4965 , C07D241/02 , A01N43/66
CPC分类号: C07D241/26 , A61K31/4965 , A61K31/497 , C07D241/32 , C07D403/12 , C07D413/12 , C07D417/12 , C07D473/00 , C07D473/16
摘要: Compounds are provided which are represented by the formula: where the structural variables are defined herein. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
摘要翻译: 提供了由下式表示的化合物:其中结构变量在本文中定义。 本发明还包括使用这些本发明的钠通道阻断剂的各种治疗方法。
-
公开(公告)号:US20050080091A1
公开(公告)日:2005-04-14
申请号:US10920410
申请日:2004-08-18
申请人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
发明人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
IPC分类号: A61K31/4965 , A61K31/497 , C07D241/26 , C07D403/12 , C07D413/12 , C07D45/02
CPC分类号: C07D241/26 , A61K31/4965 , A61K31/497 , C07D241/32 , C07D403/12 , C07D413/12 , C07D417/12 , C07D473/00 , C07D473/16
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
摘要翻译: 本发明涉及钠通道阻断剂。 本发明还包括使用这些本发明的钠通道阻断剂的各种治疗方法。
-
公开(公告)号:US20050234072A1
公开(公告)日:2005-10-20
申请号:US11131262
申请日:2005-05-18
申请人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
发明人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
IPC分类号: A61K31/4965 , A61K31/497 , C07D241/26 , C07D403/12 , C07D413/12 , C07D45/02
CPC分类号: C07D241/26 , A61K31/4965 , A61K31/497 , C07D241/32 , C07D403/12 , C07D413/12 , C07D417/12 , C07D473/00 , C07D473/16
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
-
公开(公告)号:US20060052394A1
公开(公告)日:2006-03-09
申请号:US11211422
申请日:2005-08-26
申请人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
发明人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
IPC分类号: A61K31/4965 , C07D405/02
CPC分类号: C07D241/26 , A61K31/4965 , A61K31/497 , C07D241/32 , C07D403/12 , C07D413/12 , C07D417/12 , C07D473/00 , C07D473/16
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
-
公开(公告)号:US20070032509A1
公开(公告)日:2007-02-08
申请号:US11195758
申请日:2005-08-03
申请人: Michael Johnson , Bruce Molino , Bruce Sargent , Jianzhong Zhang
发明人: Michael Johnson , Bruce Molino , Bruce Sargent , Jianzhong Zhang
IPC分类号: A61K31/4965 , C07D405/02 , C07D241/02
CPC分类号: C07D241/26 , A61K31/495 , A61K31/50 , A61K45/06
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
摘要翻译: 本发明涉及钠通道阻断剂。 本发明还包括使用这些本发明的钠通道阻断剂的各种治疗方法。
-
公开(公告)号:US20060205738A1
公开(公告)日:2006-09-14
申请号:US11211707
申请日:2005-08-26
申请人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
发明人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
IPC分类号: A61K31/4965 , C07D405/02 , A61K31/497
CPC分类号: C07D241/26 , A61K31/4965 , A61K31/497 , C07D241/32 , C07D403/12 , C07D413/12 , C07D417/12 , C07D473/00 , C07D473/16
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
-
公开(公告)号:US20060052395A1
公开(公告)日:2006-03-09
申请号:US11211660
申请日:2005-08-26
申请人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
发明人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
IPC分类号: A61K31/4965 , C07D405/02 , C07D239/42
CPC分类号: C07D241/26 , A61K31/4965 , A61K31/497 , C07D241/32 , C07D403/12 , C07D413/12 , C07D417/12 , C07D473/00 , C07D473/16
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
摘要翻译: 本发明涉及钠通道阻断剂。 本发明还包括使用这些本发明的钠通道阻断剂的各种治疗方法。
-
公开(公告)号:US20050228182A1
公开(公告)日:2005-10-13
申请号:US11138280
申请日:2005-05-27
申请人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
发明人: Michael Johnson , Bruce Molino , Jianzhong Zhang , Bruce Sargent
IPC分类号: A61K31/4965 , A61K31/497 , C07D241/26 , C07D403/12 , C07D413/12 , C07D45/02
CPC分类号: C07D241/26 , A61K31/4965 , A61K31/497 , C07D241/32 , C07D403/12 , C07D413/12 , C07D417/12 , C07D473/00 , C07D473/16
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
-
-
-
-
-
-
-
-
-