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17 条记录 (耗时 0.04 秒)

    Method for producing sulfonated aryl phosphines
    5.
    发明授权
    Method for producing sulfonated aryl phosphines 失效
    制备磺化芳基膦的方法

    公开(公告)号：US06610881B1

    公开(公告)日：2003-08-26

    申请号：US09937640

    申请日：2001-12-12

    申请人： Michael Riedel ,  Jurgen Herwig ,  Helmut Bahrmann ,  Klaus Bergrath ,  Wolfgang Zgorzel-Ski ,  Robert Eckl ,  Ernst Wiebus ,  Carl D Frohning ,  Wilfried Fenske ,  Florian Rampf

    发明人： Michael Riedel ,  Jurgen Herwig ,  Helmut Bahrmann ,  Klaus Bergrath ,  Wolfgang Zgorzel-Ski ,  Robert Eckl ,  Ernst Wiebus ,  Carl D Frohning ,  Wilfried Fenske ,  Florian Rampf

    IPC分类号： C07C30900

    CPC分类号： B01J31/2404 ,  B01J31/2409 ,  B01J31/28 ,  B01J2231/321 ,  B01J2531/822 ,  B01J2531/96 ,  C07C45/50 ,  C07F9/5022 ,  C07F9/5054 ,  C07F9/5095 ,  C07C47/02

    摘要： The invention relates to a method for producing sulfonated aryl phosphines by reacting aryl phosphines with oleum. After reacting the aryl phosphines with oleum, the sulfonation mixture is firstly diluted with water and an inert gas stream is then fed through the diluted sulfonation mixture until SO2 is no longer released from the diluted sulfonation mixture. Afterwards, the sulfonation mixture is subsequently processed in a usual manner. The invention also relates to a method for producing solutions of sulfonated aryl phosphines by reacting the aryl phosphines with oleum, diluting the sulfonation mixture with water, extracting the aqueous solution using an organic solution consisting of an amine, and subsequently carrying out a reextraction using an aqueous solution having an inorganic base. According to the invention, the solution containing aqueous sulfonated aryl phosphines is adjusted to a pH value of up to 3 by adding acid, and an inert gas stream is then fed through the aqueous solution until sulfur dioxide is no longer released. The invention additionally relates to an aqueous catalyst solution containing rhodium and an aqueous solution of sulfonated aryl phosphines, treated as defined by the invention, for carrying out the hydroformylation of olefinically unsaturated compounds, and relates to the use thereof for carrying out the same.

    摘要翻译： 本发明涉及通过使芳基膦与发烟硫酸反应制备磺化芳基膦的方法。 在芳基膦与发烟硫酸反应之后，首先用水稀释磺化混合物，然后将惰性气体流通过稀释的磺化混合物，直到SO 2不再从稀释的磺化混合物中释放出来。 之后，磺化混合物随后以常规方式进行处理。 本发明还涉及通过使芳基膦与发烟硫酸反应制备磺化芳基膦的溶液的方法，将磺化混合物与水稀释，使用由胺构成的有机溶液萃取水溶液，然后使用 具有无机碱的水溶液。 根据本发明，通过加入酸将含有磺化芳基膦水溶液的溶液的pH值调至3，然后将惰性气体流通过该水溶液直至二氧化硫不再释放。 本发明另外涉及含有铑的水性催化剂溶液和由本发明定义的磺化芳基膦的水溶液，用于进行烯属不饱和化合物的加氢甲酰化，并涉及其用于进行烯属不饱和化合物的加氢甲酰化。

    Novel Compounds That Inhibit Factor Xa Activity
    6.
    发明申请
    Novel Compounds That Inhibit Factor Xa Activity 审中-公开
    抑制因子Xa活性的新型化合物

    公开(公告)号：US20080051388A1

    公开(公告)日：2008-02-28

    申请号：US11632291

    申请日：2005-07-19

    申请人： Thilo Fuchs ,  Robert Eckl

    发明人： Thilo Fuchs ,  Robert Eckl

    IPC分类号： A61K31/445 ,  A61K31/541 ,  A61K31/55 ,  A61P7/02 ,  C07D243/08 ,  C07D405/02 ,  C07D417/02

    CPC分类号： C07H15/203

    摘要： The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts, solvates, hydrates or pharmaceutically acceptable formulations thereof. Those compounds can be used in inhibiting factor Xa and in the prevention and/or treatment of thrombolytic conditions.

    摘要翻译： 本发明涉及式（I）化合物或其药学上可接受的盐，溶剂合物，水合物或其药学上可接受的制剂。 那些化合物可用于抑制因子Xa和预防和/或治疗溶栓症状。

    Envelope-stuffing device
    7.
    发明授权
    Envelope-stuffing device 失效
    信封装置

    公开(公告)号：US5706636A

    公开(公告)日：1998-01-13

    申请号：US646253

    申请日：1996-05-10

    申请人： Robert Eckl

    发明人： Robert Eckl

    IPC分类号： B43M3/04 ,  B65B43/26

    CPC分类号： B43M3/045

    摘要： The present invention pertains to the object of substantially increasing the performance of an envelope-stuffing machine. While EP-A-0 504 114 discloses the use of rotating elements for opening the envelopes and for grasping the envelope flaps for this purpose, the present invention suggests that the opening and grasping of the envelopes (20) be performed in one conveying plane (13), and the introduction of the envelope contents (21) be performed in a conveying plane (12) arranged offset in relation thereto at another level, and that a link chain (10) with a plurality of spreading members (9) be provided between them, which is movable at right angles to the conveying planes (12, 13) and keeps the envelopes (20) picked up by the spreading members (9) ready at another point for the introduction of the envelope contents (21) and discharges them.

    摘要翻译： PCT No.PCT / EP94 / 03519 371日期：1996年5月10日 102（e）日期1996年5月10日PCT 1994年10月26日PCT公布。 WO95 / 13197 PCT出版物 日期：1995年5月18日本发明涉及显着增加包络填充机性能的目的。 虽然EP-A-0 504 114公开了为了这个目的而使用旋转元件来打开信封并且为了抓住信封襟翼，本发明提出，在一个输送平面（20）中执行信封（20）的打开和抓握 13），并且在另一个层面上在相对于其偏移设置的输送平面（12）中执行信封内容（21）的引入，并且提供具有多个扩展构件（9）的链节（10） 在它们之间，其可以与输送平面（12,13）成直角地移动，并且保持由扩展构件（9）拾取的信封（20）准备在另一个位置用于引入信封内容物（21）并将其放电 他们。

    Novel factor viia inhibiting compounds
    9.
    发明申请
    Novel factor viia inhibiting compounds 审中-公开
    新型因子viia抑制化合物

    公开(公告)号：US20060084614A1

    公开(公告)日：2006-04-20

    申请号：US10541347

    申请日：2004-01-05

    申请人： Robert Eckl ,  Lutz Weber ,  Christian Oefner

    发明人： Robert Eckl ,  Lutz Weber ,  Christian Oefner

    IPC分类号： A61K31/704 ,  C07H17/00

    CPC分类号： C07H15/203 ,  A61K31/7034

    摘要： The present invention relates to new compounds of formula (I): These compounds are very effective factor VIIa inhibitors and are therefore of interest in the treatment and/or prevention of thromboses, stroke, heart attack, inflammation, arteriosclerosis and tumour conditions.

    摘要翻译： 本发明涉及式（I）的新化合物：这些化合物是非常有效的因子VIIa抑制剂，因此对治疗和/或预防血栓形成，中风，心脏病发作，炎症，动脉硬化和肿瘤状况感兴趣。

    Method of an apparatus for unstacking a pile of sheets
    10.
    发明授权
    Method of an apparatus for unstacking a pile of sheets 失效
    用于拆卸一堆纸的装置的方法

    公开(公告)号：US4042235A

    公开(公告)日：1977-08-16

    申请号：US606206

    申请日：1975-08-20

    申请人： Rudolf Wanner ,  Robert Eckl

    发明人： Rudolf Wanner ,  Robert Eckl

    IPC分类号： B65H3/10 ,  B65H3/34 ,  G01N33/52 ,  B65H3/08

    CPC分类号： G01N33/521 ,  B65H3/10 ,  B65H3/34 ,  B65H2701/1916

    摘要： A pile of sheets arranged vertically next to one another is gently urged against a rigid metal plate that can be reciprocated back and forth very rapidly so as to pull the end sheet off the pile by suction and to return to rest against the pile of sheets before they have followed this reciprocation motion to the same extent as the end sheet. Once the plate pulls rapidly away from the end of the pile, pulling the end sheet with it, this end sheet is engaged by a suction roller and pulled laterally off the pile.

    摘要翻译： 将一堆彼此垂直排列的片材轻轻地推靠在刚性金属板上，该刚性金属板可以非常快速地来回往复运动，以便通过抽吸将端片从该桩上拉出，并在靠前的一堆片材上返回休息 他们已经按照这种往复运动与最终单相同。 一旦板从桩的端部迅速拉开，用其拉动端板，该端板通过抽吸辊接合并从桩侧向拉出。