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1.发明申请Coating Process for Drug Delivery Balloons Using Heat-Induced Rewrap Memory 有权使用热诱导重写存储器的药物递送气球的涂覆过程公开(公告)号：US20120059316A1
公开(公告)日：2012-03-08
申请号：US13225166
申请日：2011-09-02
CPC分类号： A61L29/16 , A61L2300/416 , A61L2300/45 , A61L2420/02 , Y10T29/49885
摘要： A method of producing a drug coated balloon that comprises the steps of: subjecting a balloon catheter with a folded and wrapped balloon thereon to a pre-annealing step to induce a fold/wrap memory in the resulting pre-annealed balloon; unfolding the pre-annealed balloon sufficiently to expose the full circumferential surface of the balloon by application of an inflation pressure that retains said fold/wrap memory; applying a drug coating formulation to the unfolded balloon surface; releasing pressure to relax the balloon and induce creasing along fold memory; and evacuating the balloon slowly to induce refolding and rewrapping of the balloon. The method overcomes the need to use a folding apparatus to fold and wrap a drug coated balloon.
摘要翻译： 一种制备药物包衣球囊的方法，包括以下步骤：对其上的折叠和包裹的气囊的球囊导管进行预退火步骤，以在所得预退火球囊中引起折叠/包裹记忆; 通过施加保持所述折叠/包裹存储器的充气压力来充分展开预退火球囊以暴露气球的整个圆周表面; 将药物涂层制剂施用到未折叠的气囊表面; 释放压力以放松气球，并沿折叠记忆引发褶皱; 并缓慢排空球囊以引起气球的再折叠和重新包裹。 该方法克服了使用折叠装置折叠和包裹药物涂覆的气囊的需要。
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2.发明授权Coating process for drug delivery balloons using heat-induced rewrap memory 有权使用热引起的包裹记忆的药物递送气囊的涂覆方法公开(公告)号：US08889211B2
公开(公告)日：2014-11-18
申请号：US13225166
申请日：2011-09-02
CPC分类号： A61L29/16 , A61L2300/416 , A61L2300/45 , A61L2420/02 , Y10T29/49885
摘要： A method of producing a drug coated balloon that comprises the steps of: subjecting a balloon catheter with a folded and wrapped balloon thereon to a pre-annealing step to induce a fold/wrap memory in the resulting pre-annealed balloon; unfolding the pre-annealed balloon sufficiently to expose the full circumferential surface of the balloon by application of an inflation pressure that retains said fold/wrap memory; applying a drug coating formulation to the unfolded balloon surface; releasing pressure to relax the balloon and induce creasing along fold memory; and evacuating the balloon slowly to induce refolding and rewrapping of the balloon. The method overcomes the need to use a folding apparatus to fold and wrap a drug coated balloon.
摘要翻译： 一种制备药物包衣球囊的方法，包括以下步骤：对其上的折叠和包裹的气囊的球囊导管进行预退火步骤，以在所得预退火球囊中引起折叠/包裹记忆; 通过施加保持所述折叠/包裹存储器的充气压力来充分展开预退火球囊以暴露气球的整个圆周表面; 将药物涂层制剂施用到未折叠的气囊表面; 释放压力以放松气球，并沿折叠记忆引发褶皱; 并缓慢排空球囊以引起气球的再折叠和重新包裹。 该方法克服了使用折叠装置折叠和包裹药物涂覆的气囊的需要。
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3.发明申请Implantable medical device with inductive coil configurable for mechanical fixation 有权具有感应线圈的可植入医疗器械可配置用于机械固定公开(公告)号：US20070156205A1
公开(公告)日：2007-07-05
申请号：US11326802
申请日：2006-01-05
申请人： Dennis Larson , Cheng Zhang , Keith Maile , Abhi Chavan
发明人： Dennis Larson , Cheng Zhang , Keith Maile , Abhi Chavan
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , A61B5/0031 , A61N1/37223
摘要： An embodiment of a system for gathering physiologic data related to a human body includes a sensor device implanted in the human body, an inductive coil communicably coupled to the implanted sensor device; and a manager device in communication with the implanted sensor device via the inductive coil. The coil may be wrapped around the sensor device or attached to the sensor device fixation. An embodiment of a method for gathering physiologic data related to a physiologic parameter in a human body includes communicably coupling an inductive coil to communication circuitry of an implantable medical device (IMD), deploying the inductive coil and the IMD into a vessel of the human body, and inducing current in the inductive coil via the communication circuitry, the current representative of data associated with the IMD.
摘要翻译： 用于收集与人体相关的生理数据的系统的实施例包括植入人体内的传感器装置，可感知地耦合到植入的传感器装置的感应线圈; 以及经由感应线圈与植入的传感器装置通信的管理器装置。 线圈可以缠绕在传感器装置上或附接到传感器装置固定。 用于收集与人体生理参数相关的生理数据的方法的实施例包括将感应线圈可通信地耦合到可植入医疗设备（IMD）的通信电路，将感应线圈和IMD部署到人体的容器中 ，并且经由通信电路感应电感线圈中的电流，表示与IMD相关联的数据的电流。
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4.发明申请Method and apparatus for communication between a handheld programmer and an implantable medical device 有权用于在手持编程器和可植入医疗装置之间进行通信的方法和装置公开(公告)号：US20050245992A1
公开(公告)日：2005-11-03
申请号：US10835043
申请日：2004-04-29
申请人： Kenneth Persen , Jeffrey Von Arx , Dennis Larson , Vineel Vallapureddy , Matthias Woellenstein , Jason Hein
发明人： Kenneth Persen , Jeffrey Von Arx , Dennis Larson , Vineel Vallapureddy , Matthias Woellenstein , Jason Hein
CPC分类号： A61N1/37247 , A61N1/37282
摘要： Systems and methods for telemetric communication between a handheld programmer and an implantable medical device are disclosed. A preferred embodiment comprises a user-friendly, color, touch-sensitive screen that allows the user to visually observe and control the handheld's operation. The handheld further comprises an internal and/or external analytical means to provide robust analytical capabilities. Some embodiments of a system disclosed herein can be configured as a component of an Advanced Patient Management System that helps better monitor, predict and manage chronic diseases.
摘要翻译： 公开了用于手持编程器和可植入医疗装置之间的遥测通信的系统和方法。 优选实施例包括用户友好的彩色触敏屏幕，其允许用户可视地观察和控制手持机的操作。 手持设备还包括内部和/或外部分析装置，以提供稳健的分析能力。 本文公开的系统的一些实施例可被配置为有助于更好地监测，预测和管理慢性疾病的高级患者管理系统的组件。
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