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公开(公告)号:US20110139620A1
公开(公告)日:2011-06-16
申请号:US12853906
申请日:2010-08-10
申请人: Michael STUMBER , Martina Daub , Jochen Rupp , Massimo Kubon , Peter Rothacher , Meike Moschallski , Martin Stelzle , Christian Dorrer
发明人: Michael STUMBER , Martina Daub , Jochen Rupp , Massimo Kubon , Peter Rothacher , Meike Moschallski , Martin Stelzle , Christian Dorrer
IPC分类号: C25B9/00 , G01N27/447
CPC分类号: B03C5/026 , B01F5/061 , B01F13/0076 , B01F2005/0621 , B01F2005/0636 , B01L3/502753 , B01L2200/0668 , B01L2400/0424 , B03C5/005 , C12M23/16 , C12M47/02 , C12M47/04
摘要: A microfluidic cell for the dielectrophoretic separation, accumulation, and/or lysis of polarizable bioparticles, including an interdigital electrode system composed of two electrode groups having interdigitated electrodes, and a micromixer having microchannels and microelevations. The interdigital electrode system and the micromixer are situated on the same side of the cell to improve the separation, accumulation, and/or lysis characteristics. Moreover, also described is a microfluidic system which includes such a microfluidic cell, and use thereof, and a method for separating, accumulating, and/or lysing polarizable bioparticles.
摘要翻译: 用于可极化生物颗粒的介电电泳分离,积累和/或裂解的微流体细胞,包括由具有交叉电极的两个电极组组成的叉指电极系统和具有微通道和微量消耗的微混合器。 叉指电极系统和微混合器位于细胞的同一侧,以改善分离,积累和/或裂解特性。 此外,还描述了包括这种微流体细胞的微流体系统及其用途,以及用于分离,积聚和/或裂解可极化生物颗粒的方法。
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公开(公告)号:US20110139621A1
公开(公告)日:2011-06-16
申请号:US12853920
申请日:2010-08-10
申请人: Michael Stumber , Martina Daub , Jochen Rupp , Massimo Kubon , Peter Rothacher , Meike Moschallski , Martin Stelzle , Christian Dorrer
发明人: Michael Stumber , Martina Daub , Jochen Rupp , Massimo Kubon , Peter Rothacher , Meike Moschallski , Martin Stelzle , Christian Dorrer
IPC分类号: G01N27/453 , G01N27/447
CPC分类号: G01N27/44704 , G01N27/44791
摘要: A microfluidic cell for the dielectrophoretic separation, accumulation, and/or lysis of polarizable bioparticles, including an interdigital electrode system composed of two electrode groups having interdigitated electrodes, a flat electrode in which the interdigital electrode system and the flat electrode are situated on opposite sides of the cell in order to improve the separation, accumulation and/or lysis characteristics. Moreover, a microfluidic system which includes such a microfluidic cell, and use thereof, and a method for separating, accumulating, and/or lysing polarizable bioparticles is also described.
摘要翻译: 用于可极化生物颗粒的介电电泳分离,积累和/或裂解的微流体细胞,包括由具有交叉指向电极的两个电极组构成的交叉指状电极系统,其中叉指电极系统和平面电极位于相对侧上的扁平电极 以提高分离,积累和/或裂解特性。 此外,还描述了包括这种微流体细胞的微流体系统及其用途,以及用于分离,积聚和/或裂解可极化生物颗粒的方法。
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公开(公告)号:US09034162B2
公开(公告)日:2015-05-19
申请号:US12853906
申请日:2010-08-10
申请人: Michael Stumber , Martina Daub , Jochen Rupp , Massimo Kubon , Peter Rothacher , Meike Moschallski , Martin Stelzle , Christian Dorrer
发明人: Michael Stumber , Martina Daub , Jochen Rupp , Massimo Kubon , Peter Rothacher , Meike Moschallski , Martin Stelzle , Christian Dorrer
CPC分类号: B03C5/026 , B01F5/061 , B01F13/0076 , B01F2005/0621 , B01F2005/0636 , B01L3/502753 , B01L2200/0668 , B01L2400/0424 , B03C5/005 , C12M23/16 , C12M47/02 , C12M47/04
摘要: A microfluidic cell for the dielectrophoretic separation, accumulation, and/or lysis of polarizable bioparticles, including an interdigital electrode system composed of two electrode groups having interdigitated electrodes, and a micromixer having microchannels and microelevations. The interdigital electrode system and the micromixer are situated on the same side of the cell to improve the separation, accumulation, and/or lysis characteristics. Moreover, also described is a microfluidic system which includes such a microfluidic cell, and use thereof, and a method for separating, accumulating, and/or lysing polarizable bioparticles.
摘要翻译: 用于可极化生物颗粒的介电电泳分离,积累和/或裂解的微流体细胞,包括由具有交叉电极的两个电极组组成的叉指电极系统和具有微通道和微量消耗的微混合器。 叉指电极系统和微混合器位于细胞的同一侧,以改善分离,积累和/或裂解特性。 此外,还描述了包括这种微流体细胞的微流体系统及其用途,以及用于分离,积聚和/或裂解可极化生物颗粒的方法。
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公开(公告)号:US20120031759A1
公开(公告)日:2012-02-09
申请号:US13145540
申请日:2009-01-30
申请人: Monika Hausmann , Meike Moschallski , Anton Posch , Martin Stelzle , Joerg Kentsch , Simon Werner
发明人: Monika Hausmann , Meike Moschallski , Anton Posch , Martin Stelzle , Joerg Kentsch , Simon Werner
IPC分类号: B03C5/02
摘要: A dielectrophoretic fractionation device having a channel defining a direction of flow therethrough for the fractionation of particles in a liquid particle suspension is disclosed. The device also has a deflector unit affixed to a wall of the channel and arranged to generate an electric field gradient in the channel to spatially separate the particles in the liquid particle suspension. The device also has an actuator mounted to the channel and positioned to deform the wall. Also provided is a method for inhibiting aggregation of particles in a liquid particle suspension of the dielectrophoretic fractionation device, the method including periodically deforming the wall with the actuator.
摘要翻译: 公开了一种介电电泳分级装置,其具有限定流过其中流动方向的通道,用于液体颗粒悬浮液中颗粒的分馏。 该装置还具有固定到通道的壁上的偏转器单元,并布置成在通道中产生电场梯度以在液体颗粒悬浮液中空间分离颗粒。 该装置还具有安装到通道并被定位成使壁变形的致动器。 还提供了抑制介电泳分离装置的液体颗粒悬浮液中的颗粒聚集的方法,该方法包括使致动器周期性地使壁变形。
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