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1.
公开(公告)号:US07977114B2
公开(公告)日:2011-07-12
申请号:US11240520
申请日:2005-09-30
CPC分类号: G01N30/466 , G01N30/38 , G01N30/461 , G01N30/468 , G01N2030/027 , G01N2030/628
摘要: Embodiments of the invention feature methods and apparatus for the efficient utilization of detectors and other components. The apparatus comprises a pump for receiving and propelling one or more samples in a fluid path. The apparatus further comprises a valve element in fluid communication with the pump for receiving the samples from the pump and directing the sample along one fluid path selected from a group. The group comprises a delay path comprising a delay volume, and a chromatography assembly having at least one chromatography column. The apparatus further comprises a detector or grouping of detectors in fluid communication with the delay path and the chromatography assembly for detecting compounds of interest to allow a single detector or single grouping of detectors to receive samples from the two fluid paths.
摘要翻译: 本发明的实施例的特征在于有效利用检测器和其它部件的方法和装置。 该装置包括用于在流体路径中接收和推进一个或多个样品的泵。 该装置还包括与泵流体连通的阀元件,用于从泵接收样品并沿着从组中选择的一个流体路径引导样品。 该组包括包括延迟体积的延迟路径和具有至少一个层析柱的色谱组合物。 该装置还包括与延迟路径和色谱组件流体连通的检测器或检测器组,用于检测感兴趣的化合物,以允许单个检测器或单个检测器组从两个流体路径接收样品。
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公开(公告)号:US20100065492A1
公开(公告)日:2010-03-18
申请号:US12605520
申请日:2009-10-26
IPC分类号: B01D15/38
CPC分类号: B01D15/3833 , B01D15/426 , G01N30/02
摘要: A liquid chromatography system comprising a chiral mobile phase used to separate enantiomeric molecules present in a sample is disclosed herein. In one aspect, the mobile phase comprises a chiral solvent. In another aspect, the mobile phase includes a chiral solvent but also a buffering agent. The liquid chromatography system described herein includes both high pressure liquid chromatography (HPLC) as well as high pressure capillary liquid chromatography (CapLC).
摘要翻译: 本文公开了包含用于分离存在于样品中的对映体分子的手性流动相的液相色谱系统。 在一个方面,流动相包含手性溶剂。 在另一方面,流动相包括手性溶剂,但也包括缓冲剂。 本文所述的液相色谱系统包括高压液相色谱(HPLC)以及高压毛细管液相色谱(CapLC)。
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公开(公告)号:US07628920B2
公开(公告)日:2009-12-08
申请号:US10599583
申请日:2005-04-06
IPC分类号: B01D15/08
CPC分类号: B01D15/3833 , B01D15/426 , G01N30/02
摘要: A liquid chromatography system comprising a chiral mobile phase used to separate enantiomeric molecules present in a sample is disclosed herein. In one aspect, the mobile phase comprises a chiral solvent. In another aspect, the mobile phase includes a chiral solvent but also a buffering agent. The liquid chromatography system described herein includes both high pressure liquid chromatography (HPLC) as well as high pressure capillary liquid chromatography (CapLC).
摘要翻译: 本文公开了包含用于分离存在于样品中的对映体分子的手性流动相的液相色谱系统。 在一个方面,流动相包含手性溶剂。 在另一方面,流动相包括手性溶剂,但也包括缓冲剂。 本文所述的液相色谱系统包括高压液相色谱(HPLC)以及高压毛细管液相色谱(CapLC)。
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公开(公告)号:US20080237130A1
公开(公告)日:2008-10-02
申请号:US10599583
申请日:2005-04-06
CPC分类号: B01D15/3833 , B01D15/426 , G01N30/02
摘要: A liquid chromatography system comprising a chiral mobile phase used to separate enantiomeric molecules present in a sample is disclosed herein. In one aspect, the mobile phase comprises a chiral solvent. In another aspect, the mobile phase includes a chiral solvent but also a buffering agent. The liquid chromatography system described herein includes both high pressure liquid chromatography (HPLC) as well as high pressure capillary liquid chromatography (CapLC).
摘要翻译: 本文公开了包含用于分离存在于样品中的对映体分子的手性流动相的液相色谱系统。 在一个方面,流动相包含手性溶剂。 在另一方面,流动相包括手性溶剂,但也包括缓冲剂。 本文所述的液相色谱系统包括高压液相色谱(HPLC)以及高压毛细管液相色谱(CapLC)。
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5.
公开(公告)号:US20060093521A1
公开(公告)日:2006-05-04
申请号:US11240520
申请日:2005-09-30
IPC分类号: G01N30/02
CPC分类号: G01N30/466 , G01N30/38 , G01N30/461 , G01N30/468 , G01N2030/027 , G01N2030/628
摘要: Embodiments of the invention feature methods and apparatus for the efficient utilization of detectors and other components. The apparatus comprises a pump for receiving and propelling one or more samples in a fluid path. The apparatus further comprises a valve element in fluid communication with the pump for receiving the samples from the pump and directing the sample along one fluid path selected from a group. The group comprises a delay path comprising a delay volume, and a chromatography assembly having at least one chromatography column. The apparatus further comprises a detector or grouping of detectors in fluid communication with the delay path and the chromatography assembly for detecting compounds of interest to allow a single detector or single grouping of detectors to receive samples from the two fluid paths.
摘要翻译: 本发明的实施例的特征在于有效利用检测器和其它部件的方法和装置。 该装置包括用于在流体路径中接收和推进一个或多个样品的泵。 该装置还包括与泵流体连通的阀元件,用于从泵接收样品并沿着从组中选择的一个流体路径引导样品。 该组包括包括延迟体积的延迟路径和具有至少一个层析柱的色谱组合物。 该装置还包括与延迟路径和色谱组件流体连通的检测器或检测器组,用于检测感兴趣的化合物,以允许单个检测器或单个检测器组从两个流体路径接收样品。
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